Jump to content
  • Sign Up
0
dhiltonlittle

Aga And Dgp Differences?

Rate this topic

Recommended Posts

what is the difference between the AGA (IGA) anti gliadin antibody and the DGP deamidated gliadin pedtide antibody?

what exactly are they?

Share this post


Link to post
Share on other sites

what is the difference between the AGA (IGA) anti gliadin antibody and the DGP deamidated gliadin pedtide antibody?

what exactly are they?

This is covered in Dr. Peter Green's new book. The DGP is a newer version of the AGA test and, supposedly, a more sensitive test. I don't have the book with me so cannot provide a direct quote but that's essentially it. The AGA is still a good test but the DGP is better and may replace the AGA.

The AGA test looks for the gliadin protein in your blood, which happens if you are eating gluten and have Celiac Disease.

It is used to help diagnose and then used in re-testing to see if you are compliant to the diet.

Share this post


Link to post
Share on other sites

I just received Dr. Green's new (revised) book today. This is what he says:

Deamidated Gliadin Peptides (DGP)

Patients with celiac disease create antibodies to gliadin, but these antibodies can also be found in other conditions and in normal people. It is known that tTG deamidates, that is , it acts on and enhances the gliadin peptide in patients with celiac disease which causes the inflammatory reaction in the gut. The new ELISA test looks for these specific antibodies to deamidated gliadin.

Share this post


Link to post
Share on other sites

(cont'd) had an oops...

The new ELISA test looks for these specific antibodies to deamidated gliadin.

The DGP test is a significant and valuable new addition to the celiac panel. Many labs have changed over to it. It is also being studied to replace AGA antibody testing in young children who may not yet have developed tTG antibodies.

Share this post


Link to post
Share on other sites

Interesting they admit that the ttg test is not good in small children...

Also, Dr. Ford writes about the deamidated gliadin antibody test on his website, google ford gluten.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
0

×