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jasonD2

Mom Is Negative For Celiac

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after torturing her for a yr she finally got the test and is negative on both serology & genetic. i am surprised since all the women on my moms side have stomach problems and my maternal grandma & great grandma died from colon cancer...so is it possible the DQ8 gene skipped a generation and went to me? my paternal grandmother also had colon cancer. im confused but glad my mother is ok- shes 65 and is healthier than me :)

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Genes don't skip generations, they can't. The phenotypic expression of a gene can skip a generation easily if it is a recessive (not automatically expressed in the offspring if the other parent provides a more dominant copy) but that is not what the tests look for. It's not all that improbable that your mom's mother does have 1 copy of the gene but didn't pass it down to your mother while your father's mother had the gene as well and did pass it down to your father who gave it to you.

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