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Allergy Testing Followed Up By Unexpected Reaction


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Looking for answers Contributor

Last week I had skin testing done to rule out food allergies. My GI insisted on this just to be safe. I had no signs of allergic reaction during the test (and this inlcuded gluten, which I didn't realize until it was too late). However, later that night (8-hours later) I got what I can only explain as "internally itchy." This is a feeling I get every now and again...I remember the last time it was after I drank a coffee from a machine that was flavored. Anyways, I feel very acidic, my scalp starts to itch, my clothes bother me, I have to take off my jewelry...etc. Then, I get cold and I have to go pee every 15 minutes. I also get insomnia when I go through these spells.

Anyone had anything similar. The only thing that knocks this out is benadryl(sp?) so I'm sure it's some sort of allergic reaction...

Please share your thoughts/stories.


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GlutenFreeManna Rising Star

I had the same thing happen after my skin prick tests which included all the gluten grains--I was itchy all over. I also had nothing show up on the skin prick test but blood allergy tests found a wheat allergy. My allergist said the blood tests are slightly more accurate/sensitive to catch food allergies. I'm assuming that's why I was itchy all over. I itched for two days after my skin prick test. Benedryl helped with the itching. I did not have that cold feeling/needing to pee, however. I don't know what that could be from, unless you actually have a high fever and feel cold from it? There were times when I had hives/an allergic reaction that my body also reacted by having a fever that felt like I was freezing cold.

Looking for answers Contributor

I had the same thing happen after my skin prick tests which included all the gluten grains--I was itchy all over. I also had nothing show up on the skin prick test but blood allergy tests found a wheat allergy. My allergist said the blood tests are slightly more accurate/sensitive to catch food allergies. I'm assuming that's why I was itchy all over. I itched for two days after my skin prick test. Benedryl helped with the itching. I did not have that cold feeling/needing to pee, however. I don't know what that could be from, unless you actually have a high fever and feel cold from it? There were times when I had hives/an allergic reaction that my body also reacted by having a fever that felt like I was freezing cold.

That's interesting, thank you. Also interesting that my blood test showed major allergy to egg whites, but that didn't appear with the skin test. I guess they must not be accurate.

StephanieL Enthusiast

That's interesting, thank you. Also interesting that my blood test showed major allergy to egg whites, but that didn't appear with the skin test. I guess they must not be accurate.

Any positive allergy test, be it skin testing OR blood, is only about 50% accurate. A negative is about 92% accurate. We have a LONG way to go studying immunology! The only 100% accurate "test" for food allergies is a food challenge UNDER a Dr's care!

GlutenFreeManna Rising Star

Any positive allergy test, be it skin testing OR blood, is only about 50% accurate. A negative is about 92% accurate. We have a LONG way to go studying immunology! The only 100% accurate "test" for food allergies is a food challenge UNDER a Dr's care!

That's so true-- the blood test are not 100%. I have delevoped an anaphylactic reaction to milk so bad I have to carry an epipen, yet when I did the allergy tests and blood test milk did NOT show up as an allergy. Nevertheless my allergist says to not eat milk products and if I want to retest in the future to see if I can eat it again I have to go into the dr's office and challenge with milk while they stand by with an epi-pen. That's the ONLY 100% test for food allergies according to my allergist.

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      I'm not saying this is what you have, but your description reminds me of Morgellons, which are not very well understood. Here is a review from a reputable source. If it seems similar to your experience, you could raise this question with your Dr.  https://my.clevelandclinic.org/health/diseases/morgellons-disease
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      Hello Russ! Thank you so much for your reply.  I have not had an antibody test done, ever, relating to gluten. Last year I had an allergy test done via blood draw (as my insurance wouldn't cover the skin test) but this was for pollen and grasses, not food. Even on the blood test I had extremely high levels of reactions to each allergen. Could this seasonal allergy inflammation be contributing to my celiac inflammation? I am so careful, there is no way I could ingest gluten. For example, couple of months ago I tried a cough drop that says it was gluten free. I checked ingredients, it seemed fine. But just taking one of those caused me to have nausea, vomiting, and the same extreme abdominal pain. Have you ever heard of anyone else having symptoms like mine after being diagnosed celiac and strictly gluten free? The last episode I had like this was yesterday, after I ate a certified gluten-free coconut macaroon with a little chocolate on it. I have eaten coconut and chocolate before with no issue,  so I didn't see how I could all of a sudden have such a strong response. 
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