Celiac.com Sponsor (A1):

Celiac.com Sponsor (A1-m):

  • Join Our Community!

    Ask us a question in our celiac / gluten-free forum.

  • Scott Adams

    Effort to Redefine Type 1 Diabetes Care Has Implications for Celiac Disease

    Scott Adams
    Reviewed and edited by a celiac disease expert.

      Healthcare professional and patient campaigns emphasize benefits of screening for early-stage type 1 diabetes.

    Image: CC0 1.0--cogdogblog
    Caption: Image: CC0 1.0--cogdogblog

    Celiac.com 11/16/2020 - Type 1 diabetes (T1D), is an autoimmune disease that affects about 1.6 million Americans. People with a family history of T1D face a 15 times higher risk of developing T1D than people without a family history. Up to 20% of those with T1D may also have celiac disease.

    In an effort to redefine patient care in type 1 diabetes (T1D), Provention Bio, Inc., a biopharmaceutical company dedicated to intercepting and preventing autoimmune disease, has launched two complementary national disease state and screening education campaigns.

    Celiac.com Sponsor (A12):

    Celiac.com Sponsor (A12-m):

    The programs, titled, "Connected by T1D" and "Type 1 Tested," are designed to help healthcare professionals, patients and relatives with elevated risk of T1D to better understand the importance of early-stage, pre-symptomatic disease screening for people with a family history of T1D.

    Early blood screening for specific autoantibodies can spot early-stage T1D before any signs or symptoms appear.  Early diagnosis and treatment can help patients prepare in advance to live with diabetes, and may lower the risk of potentially deadly T1D-related problems, such as diabetic ketoacidosis. 

    Both campaigns highlight the importance of early screening for patients at greater risk due to family history of T1D. "Connected by T1D" also focuses on the different stages of T1D, along with beta cell destruction that occurs months and years prior to the onset of symptoms. "Type 1 Tested" emphasizes that early testing gives parents, patients and their doctors the knowledge needed to prepare in advance for clinical T1D, and make decisions to reduce the chances of diabetic ketoacidosis and other serious problems. 

    Both campaigns encourage early and routine autoantibody screening for people with family history of T1D.

    "We hope this national educational effort will inspire behavioral change by challenging the standard clinical practice with respect to T1D, and encourage autoantibody screening for relatives of people living with the disease," said Eleanor (Leni) Ramos, MD, CMO, Provention Bio. 

    Provention Bio, Inc. (Nasdaq: PRVB) is a biopharmaceutical company whose main investigational drug, teplizumab, designed to delay or prevention of insulin-dependent type 1 diabetes (T1D) in at-risk patients during the pre-symptomatic phase of the disease is currently under review by FDA.

    Efforts to screen and preemptively treat autoimmune diseases like T1D hold promise of similar approaches to screening and treating celiac disease, especially in first degree relatives, before damage can begin.

    Read more at PRnewswire.com. Stay tuned for more on this and related stories.



    User Feedback

    Recommended Comments

    There are no comments to display.

    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Add a comment...

    ×   Pasted as rich text.   Restore formatting

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.

  • About Me

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):

    Celiac.com Sponsors (A17-m):

  • Related Articles

    Dr. Vikki Petersen D.C, C.C.N
    Celiac.com 10/27/2017 - It has long been understood that two autoimmune diseases, celiac disease and type 1 diabetes are related. They share common genes and the incidence of celiac disease is higher among type 1 diabetics. There have been some anecdotal reports regarding children diagnosed with type 1 diabetes who were put on a gluten-free diet soon after their diagnosis and for a period of two years or more didn't require any insulin. The thought was that the gluten-free diet effectively halted the progression of the diabetes, at least for the duration of the study.
    Studies of mice have shown that despite utilizing a genetic strain of mice that were...

    Jefferson Adams
    Celiac.com 01/30/2019 - Children who receive the rotavirus vaccine may be less likely to develop type 1 diabetes than children who remain unvaccinated, a recent Australian study suggests. Rotavirus can cause severe watery diarrhea, vomiting, fever, and abdominal pain. In some cases, the virus can leave kids with dehydration that is serious enough to require a hospital visit. 
    There is some data to indicate that rotavirus infections can accelerate the development of type 1 diabetes, though researchers don’t yet know why.
    In May, 2007, health officials introduced a routine oral rotavirus vaccine for infants six weeks and older. In the most...

    Jefferson Adams
    Celiac.com 07/04/2019 - There's been some data to suggest that gluten may play a role in diabetes, but there really isn't much data on the role of gluten in type 1 diabetes (T1D), so a team of researchers recently set out to test whether gluten plays a role in type 1 diabetes onset. Specifically, the team wanted to know if a gluten-free diet can decelerate the decline in beta-cell capacity in newly diagnosed non-celiac children with T1D.
    The research team included Vít Neuman, Stepanka Pruhova, Michal Kulich, Stanislava Kolouskova, Jan Vosahlo, Martina Romanova, Lenka Petruzelkova, Barbora Obermannova, Ondrej Cinek, and Zdeněk Šumník. They are v...

    Jefferson Adams
    Celiac.com 09/30/2019 - We know from recent studies that high gluten intake in infancy can raise risk for celiac disease, and we know that the amount of gluten eaten by infants at 18 months heavily influences their risk of developing type 1 diabetes later in life.
    An earlier study conducted in Denmark suggested that a high maternal gluten consumption during pregnancy increased the risk of type 1 diabetes in the child.  
    Until now, researchers have not looked at levels of gluten intake by both the mother during pregnancy and the child in early life, and how that influences risk of developing type 1 diabetes in childhood. 
    Now, a ...