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Treating Celiac With Psychedelic Drugs?


poneelovesyou

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poneelovesyou Newbie

So, I know what youre thinking, madness! BUT, after reading this paper recently, I started  to think a bit.

 

Open Original Shared Link

 

So recently I realized that gluten was the cause of my lifelong struggle with depression and anxiety. I also have some evidence that I may be a celiac, but I am not willing to do the gluten challenge in order to find out. Regardless of it I am or not, there are 2 things that have erradicated chemical depression and anxiety from my life: Psychedelic drugs and a gluten-free diet. So the paper above is really interesting because it talks about a psychedelic (DOI) that primarily operates through the 5HT2a receptor (as do the classical psychedelic drugs such as LSD, psilocybin, DMT, mescaline etc). So they observed that through this receptor acitivity specifically, anti-inflammatory effects were observed in specific tissues in the body. One of these areas was the small intestine.

 

Still following me? So, in theory, other 5HT2a agonist may also facilitate this same anti inflammatory effect in the small intestine. obviosuly inflammation of the gut is one of the things that plagues celiacs and NCGS people, so I'm wondering if perhaps psychedelics and a gluten-free diet were treating my depression through the same mechanism; reducing inflammation in the small intestine (and perhaps other areas in the gut?)

 

So now I'm wondering, could psychedelic drugs be a potential candidate to reduce the gut inflammation in celiac disease patients? It seems like these cascading inflammatory processis are what takes so long for the body to get under control even after removing gluten from the diet, and continue to do damage to the body. What do you guys think?


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ravenwoodglass Mentor

The only way something like that would be feasible is if they were able to remove the psychedelic aspect of the drug. I don't think the general population would get much done during the day while they were watching the walls turn colors and their grasp on the reality around them was oozing away. Psychedelic drugs can also be dangerous for people with certain mental health issues. 

mommida Enthusiast

There would have to be many more years of research before I would trust be treated with psychedelic drug treatment.  I have seen LSD proposed as possible treatment for other disorders an health conditions.

 

I hope you are taking extreme precautions, because I do not believe you are under a doctor's care for your experimentations.  I have seen people completely "bake" their brains on drugs to the point they need to be kept in an institution.  Look at Ozzy Osbourne, he can't really speak anymore, but his family is wealthy enough to have servants care for some of the extreme behavior.  Don't forget his wife admits to a few times he has tried to kill her.

 

There has been research in a home, were a gluten free diet improved some mental disorders and most here have experienced a withdrawal period removing gluten from the diet.   

 

You might wan to look further into the "gut - brain connection theories"  or first brain? gut/mind

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