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Can Celiac Disease Impair Drug Therapy in Patients?

Scott Adams

By Scott Adams
in Publications & Publicity

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Scott Adams Grand Master
Scott Adams
Posted
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Celiac disease is associated with numerous chronic conditions, such as anemia and malabsorption of some critical vitamins. Changes in the gastrointestinal tract, rates of gastric emptying, and gastric pH are responsible for impaired vitamin and mineral absorption.

Intestinal CYP3A4 levels may also be disrupted, which may have implications in first-pass metabolism for some drugs that are substrates for this drug metabolizing enzyme.

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    • Joel K
      Forum Rules

      By Joel K · Posted

      Okay.  That doesn't answer the question, but thanks anyway.
    • MelissaClinPsyD
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      By MelissaClinPsyD · Posted

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    • DanteZaffar
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      By DanteZaffar · Posted

      Do you think it’s a vitamin issue that could make celiac symptoms worse during recovery ? 
    • trents
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      By trents · Posted

      Multivitamin products are seldom potent to offset the vitamin and mineral deficiencies that typically result from long term undiagnosed celiac disease. We commonly recommend sublingual B12, a B-complex 5-10k IU of D3, 400 mg daily of magnesium glycinate, and zinc picolinate. The forms of certain vitamins like magnesium and zinc are important since it has a significant impact on absorbability. If you live near a Costco, the Kirkland Signature series and Nature Made lines are good quality choices and economical. And they will indicate on the packaging if they are gluten free.
    • DanteZaffar
      Young celiac person looking for advice

      By DanteZaffar · Posted

      I’ve been taking a multivitamin however my doctors appointment is not available till next month for any specific vitamin tests 
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