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Enterolab Results Advice


dermgirl

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dermgirl Rookie

Hello,

I am new to this group and the world of glutens. I need help. I had a negative blood test one month ago for Celiac. I just received my test results form Enterolab yesterday. I will post those below. I have a dr. appt April 5 to see a gastro. I visit with him, and I have a scopes scheduled. Should I continue to eat gluten until after this tests?

A) Gluten Sensitivity Stool and Gene Panel Complete *Best test/best value

Fecal Anti-gliadin IgA: 17 Units

Fecal Anti-tissue Transglutaminase IgA: 5 Units

Quantitative Microscopic Fecal Fat Score: Less than 300 Units

Fecal Anti-casein (cow's milk) IgA: 7 Units

HLA-DQB1 Molecular analysis, Allele 1: 0201

HLA-DQB1 Molecular analysis, Allele 2: 0301

Serologic equivalent: HLA-DQ 2,3 (Subtype 2,7)

Interpretation of Fecal Anti-gliadin IgA (Normal Range is less than 10 Units): Intestinal antigliadin IgA antibody was elevated, indicating that you have active dietary gluten sensitivity. For optimal health, resolution of symptoms (if you have them), and prevention of small intestinal damage and malnutrition, osteoporosis, and damage to other tissues (like nerves, brain, joints, muscles, thyroid, pancreas, other glands, skin, liver, spleen, among others), it is recommended that you follow a strict and permanent gluten free diet. As gluten sensitivity is a genetic syndrome, you may want to have your relatives screened as well.

Interpretation of Fecal Anti-tissue Transglutaminase IgA (Normal Range is less than 10 Units): The level of intestinal IgA antibodies to the human enzyme tissue transglutaminase was below the upper limit of normal, and hence, there is no evidence of a gluten-induced autoimmune reaction.

Interpretation of Quantitative Microscopic Fecal Fat Score (Normal Range is less than 300 Units): Provided that dietary fat is being ingested, a fecal fat score less than 300 indicates there is no malabsorbed dietary fat in stool indicating that digestion and absorption of nutrients is currently normal.

Interpretation of Fecal Anti-casein (cow's milk) IgA (Normal Range is less than 10 Units): Levels of fecal IgA antibody to a food antigen greater than or equal to 10 are indicative of an immune reaction, and hence immunologic "sensitivity" to that food. For any elevated fecal antibody level, it is recommended to remove that food from your diet. Values less than 10 indicate there currently is minimal or no reaction to that food and hence, no direct evidence of food sensitivity to that specific food. However, because 1 in 500 people cannot make IgA at all, and rarely, some people can still have clinically significant reactions to a food antigen despite the lack of a significant antibody reaction (because the reactions primarily involve T cells), if you have an immune syndrome or symptoms associated with food sensitivity, it is recommended that you try a strict removal of suspect foods from your diet for up to 12 months despite a negative test.

Interpretation Of HLA-DQ Testing: HLA-DQB1 gene analysis reveals that you have one of the main genes that predisposes to gluten sensitivity and celiac sprue, HLA-DQB1*0201 or HLA-DQB1*0302. Each of your offspring has a 50% chance of receiving this gene from you, and at least one of your parents passed it to you. You also have a non-celiac gene predisposing to gluten sensitivity (any DQ1, DQ2 not by HLA-DQB1*0201, or DQ3 not by HLA-DQB1*0302). Having one celiac gene and one gluten sensitive gene, means that each of your parents, and all of your children (if you have them) will possess at least one copy of a gluten sensitive gene. Having two copies also means there is an even stronger predisposition to gluten sensitivity than having one gene and the resultant immunologic gluten sensitivity or celiac disease may be more severe.

For more information about result interpretation, please see Open Original Shared Link

Stool Analysis performed by: Frederick Ogunji, Ph.D., EnteroLab

Molecular Gene Analysis performed by: American Red Cross

Interpretation of all results by: Kenneth D. Fine, M.D., EnteroLab

Thank You For Allowing EnteroLab to Help You Attain Optimum Intestinal And Overall Health.

Thanks fo your help


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ksymonds84 Enthusiast

If it were me and I could handle it, I would keep eating at least one piece of gluten bread a day to get the most accurate diagnoses. Having said that, I caved in two weeks before my biopsy because the pain and bloating were killing me. Thanks goodness it was still enough to get my answer. However; It is still possible to get a false negative from the biopsy because your intestines are so long and they only take so many samples for celiac. My local Celiac chapter does recommend Dr. Fine's test to those who test negative on everything else but still have symptoms. Enterolab does not diagnose celiac but can tell you if you are sensitive go gluten. Good luck and let us know how it all turns out.

ravenwoodglass Mentor

The first part of your test, the IGA, is saying that you are reacting to gluten. The negative Ttg is good news as it says that means your not yet having autoimmune impact. Do keep eating your full gluten diet until you see the GI if you are planning on having a scope done. After your testing is done do go gluten free, you don't have to wait on the results.

michelley65 Rookie

Can anyone tell me how to get an Enterolab test done?Is it something you do at home,or is it something a doctor does?I had my celiac test done thismorning,but I am pretty sure that its not celiac,but a sensitivity to gluten.Im starting to wonder what exactly is the difference between the two,because even if you have a sensitivity to it..you are doomed if you eat more than one cracker a day!I eat graham crackers for breakfast,which contain gluten..and Im okay unless I have anything else throughout the day.For instance,today..a graham cracker for breakfast..gluten free cereal for lunch,gluten-free fruit bites for a snack..then for dinner I ate chili.and it all started!!I guess the chili seasoning has gluten.Any advice?

dermgirl Rookie

Can anyone tell me how to get an Enterolab test done?Is it something you do at home,or is it something a doctor does?I had my celiac test done thismorning,but I am pretty sure that its not celiac,but a sensitivity to gluten.Im starting to wonder what exactly is the difference between the two,because even if you have a sensitivity to it..you are doomed if you eat more than one cracker a day!I eat graham crackers for breakfast,which contain gluten..and Im okay unless I have anything else throughout the day.For instance,today..a graham cracker for breakfast..gluten free cereal for lunch,gluten-free fruit bites for a snack..then for dinner I ate chili.and it all started!!I guess the chili seasoning has gluten.Any advice?

Hello,

Here is the link to Enterolab: Open Original Shared Link

They send you a kit and you send the samples back to them. It took exactly 3 weeks to get the results. I do not know as of yet if my insurance will pay, but I feel it was worth every dollar I spent. Now I know I am not nuts!

I had a blood test done for Celiac, it was negative. I know I am sick, I have had symptons since I was 7...now 46. Hashimotos, skin issues, and chronic diarrhea and sometimes a horrible gas bubble under my right ribs. I am scheduled for scopes in April. I am fortunate that my Doc supports the Enterolab's testing. I will eat a complete Gluten-Free diet as soon as my scopes are done.

michelley65 Rookie

Hello,

Here is the link to Enterolab: Open Original Shared Link

They send you a kit and you send the samples back to them. It took exactly 3 weeks to get the results. I do not know as of yet if my insurance will pay, but I feel it was worth every dollar I spent. Now I know I am not nuts!

I had a blood test done for Celiac, it was negative. I know I am sick, I have had symptons since I was 7...now 46. Hashimotos, skin issues, and chronic diarrhea and sometimes a horrible gas bubble under my right ribs. I am scheduled for scopes in April. I am fortunate that my Doc supports the Enterolab's testing. I will eat a complete Gluten-Free diet as soon as my scopes are done.

Thankyou!!!Im not sure if I will do the test or not...Im starting to realize that it doesnt really matter what a test says,but how I feel when I dont eat gluten..so Im just going gluten free and feeling better.

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    • trents
      Yes, it does. And joint pain is another celiac symptom that is now well-recognized. 
    • ThomasA55
      Does my iron loss sound like celiac to you?
    • trents
      Being as how you are largely asymptomatic, I would certainly advise undertaking a gluten challenge in order to get formal testing for celiac disease. We have many forum participants who become violently ill when they undertake a gluten challenge and they therefore can't carry through with it. That doesn't seem to be the case with you. The reason I think it is important for you to get tested is that many or most people who don't have a formal diagnosis find it difficult to be consistent with the gluten-free diet. They find ways to rationalize that their symptoms are due to something other than celiac disease . . . especially when it becomes socially limiting.  The other factor here is by being inconsistent with the gluten free diet, assuming you do have celiac disease, you are likely causing slow, incremental damage to your gut, even though you are largely asymptomatic. It can take years for that damage to get to the point where it results in spinoff health problems. Concerning genetic testing, it can't be used for diagnosis, at least not definitively. Somewhere between 30 and 40% of the general population will have one or both of the two genes known to be associated with the development of active celiac disease. Yet, only about 1% of the general population will develop active celiac disease. But the genetic testing can be used as a rule out for celiac disease if you don't have either gene. But even so, that doesn't eliminate the possibility of having NCGS (Non Celiac Gluten Sensitivity).
    • ThomasA55
    • trents
      Welcome to the celiac.com community, @ThomasA55! Before I give my opinion on your question about whether or not you should undergo a gluten challenge, I would like to know how you react when you get a good dose of gluten? Are you largely asymptomatic or do you experience significant illness such as nausea and diarrhea? You mentioned intermittent joint pain before you began experimenting with a low gluten diet. Anything else?
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