RMJ

You’re a good friend. I’d ask her what she prefers, and if she hesitates about having you cook for her, don't push it. I will eat at my brother’s, but they check ingredients with me and I look at anything packaged.

The immune system changes during pregnancy so perhaps that is why your reaction was different. Best to stay gluten free until you’ve had the baby.

You were feeling better on the gluten free diet then decided to cheat and now feel worse? Why not just stay on the gluten free diet?

If you are gluten free, it takes weeks of eating gluten to get the antibodies to a level where they can be measured.

You could try going gluten free for 6 months and see if the TTG levels go down.

It is possible to have systemic reactions from skin prick tests, but they are usually happen along with a positive skin reaction. Here is some info about ragweed/banana and itchy mouth. https://www.aaaai.org/conditions-and-treatments/library/allergy-library/outdoor-food-allergies-relate

My DGP antibodies decreased but remained stubbornly in the positive range until I tried the Fasano diet. I know it comes up regularly in the forums but I don’t know if there is a specific thread on it. The reason for waiting 4 weeks is to allow the villi to heal, since the enzyme that digests lactose is from the tips of the villi. After 3 months it is probably worth a try. There are some adults without celiac who can’t handle dairy. Ask away with your questions!

Not everyone is positive on the tTG test. Some are only positive on the DGP test (deamidated gliadin peptides). She might still have celiac, or it might be non celiac gluten sensitivity.

I’m not sure what you mean by “her IgA is within normal range.” Is that total IgA, TTG IgA or DGP IgA? Were there any IgG tests? p.s. your English is fine!

I used to develop tests like this. To develop a celiac blood test you take blood samples from a bunch of people with biopsy-diagnosed disease, and a bunch of samples from people without celiac. You run the test on all of them. Then you figure out where to make the healthy/celiac cutoff so that you get the right answer (matches biopsy) most of the time. Can a positive be wrong? Yes, but usually not. One way to evaluate is to go gluten free and retest at the same lab and see if there is a BIG difference. A small difference could just be variability of the test. Run the same sample 3 times and you’ll probably get 3 slightly different numbers.

Thanks, I will have to try these.

OD stands for optical density. When the test is run it is evaluated in a machine which reads a color and gives results in OD units. Most blood tests have absolute units such as mg per deciliter, a weight per volume of blood. Celiac tests are not standardized. The units are arbitrary based on the machine used to read it. Thus each manufacturer has their own range of what is normal and what indicates celiac. You cannot compare your results with the range from a different lab or test manufacturer.

I’m curious, what is the purpose of soaking in water?

You could try the gluten free diet and see if the antibody levels go down, that would certainly indicate that they were related to gluten in your diet.

Hives that respond to an antihistamine are from IgE antibodies, whereas celiac is IgG or IgA. One can respond to wheat with all types of antibodies - you might have an allergy plus celiac.