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How Long Do I Have To Gluten-Load Before A Test?

ladolcevita

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ladolcevita Newbie
ladolcevita
Posted

How long do I have to be eating gluten before I can go in for a blood test for celiac?

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kareng Grand Master
kareng
Posted

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"What is a gluten challenge?

A gluten challenge is the period of time when gluten is added back into a person’s diet to assist in the diagnosis of celiac disease. Antibodies take time to build into the blood stream before they can be detected through blood analysis. For a gluten challenge we recommend eating 1/2 slice of bread or a cracker each day for the duration of the challenge.

  • Prior to blood testing we recommend 12 weeks of eating gluten.
  • Prior to an endoscopic biopsy we recommend 2 weeks of eating gluten.

In the case of a severe reaction to gluten, a medical professional may opt to shorten the 12-week challenge and move immediately to an endoscopic biopsy."

ladolcevita Newbie
ladolcevita
Posted
  • Author

Open Original Shared Link

 

 

"What is a gluten challenge?

A gluten challenge is the period of time when gluten is added back into a person’s diet to assist in the diagnosis of celiac disease. Antibodies take time to build into the blood stream before they can be detected through blood analysis. For a gluten challenge we recommend eating 1/2 slice of bread or a cracker each day for the duration of the challenge.

  • Prior to blood testing we recommend 12 weeks of eating gluten.
  • Prior to an endoscopic biopsy we recommend 2 weeks of eating gluten.

In the case of a severe reaction to gluten, a medical professional may opt to shorten the 12-week challenge and move immediately to an endoscopic biopsy."

I've been eating gluten for pretty much my entire life except for these past 2 weeks which I've decided to go glutenfree to potentially help another autoimmune disease I have. But now I'm curious as to whether I really have Celiac so I'm thinking to go in for a blood test. Do I have to continue eating gluten for the next 12 weeks, or it is okay to just go in now since I've only been gluten free for a short amount of time? 

kareng Grand Master
kareng
Posted

I've been eating gluten for pretty much my entire life except for these past 2 weeks which I've decided to go glutenfree to potentially help another autoimmune disease I have. But now I'm curious as to whether I really have Celiac so I'm thinking to go in for a blood test. Do I have to continue eating gluten for the next 12 weeks, or it is okay to just go in now since I've only been gluten free for a short amount of time? 

 

 

No one can really say.  Lots of people still have high antibodies after a few months gluten-free.  Its hard to know how your body is reacting.

 

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moosemalibu Collaborator
moosemalibu
Posted

I would continue to eat it and get blood tested (as already described by Karen) to be sure. If the test were negative would you always wonder if it was a false negative? I would... just a thought.

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      By knitty kitty · Posted

      Hello, @Aretaeus Cappadocia, My favorite source of B12 is liver.  😺 I react to nutritional yeast the same way as if I were glutened.  Casein, a protein in dairy, and nutritional yeast have protein segments that match certain antigenic protein segments in gluten.  The proteins in rice, corn (maize), and chicken meat have them as well.   Some people with Celiac might tolerate them without a problem, but I need to avoid them.  For those still having symptoms, cutting these out of our diet may improve symptoms. 
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      By ainsleydale1700 · Posted

      Thank you, that is helpful! 
    • Scott Adams
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      HLA testing can definitely be confusing. Classic celiac disease risk is most strongly associated with having the full HLA-DQ2 or HLA-DQ8 heterodimer, which requires specific DQA1 and DQB1 genes working together. Your report shows you are negative for the common DQ2 and DQ8 combinations, but positive for DQB102, which is one component of the DQ2 pair. On its own, DQB102 does not usually form the full DQ2 molecule most strongly linked to celiac disease, which is likely why your doctor said you do not carry the typical “celiac genes.” However, genetics are only part of the picture. A negative gene test makes celiac disease much less likely, but not absolutely impossible in rare cases. More importantly, both antibody testing and biopsy are only reliable when someone is actively eating gluten; being gluten-free for four years before testing can cause both bloodwork and intestinal biopsy to appear falsely negative. Given your positive antibodies and ongoing symptoms, it may be reasonable to seek clarification from a gastroenterologist experienced in celiac disease about whether proper gluten exposure was done before testing and whether additional evaluation is needed.
    • Aretaeus Cappadocia
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      By Aretaeus Cappadocia · Posted

      I agree with your post and have had similar experiences. I'm commenting to add the suggestion of also using nutritional yeast as a supplement. It's a rich source of B vitamins and other nutrients, and some brands are further supplemented with additional B12. I sprinkle a modest amount in a variety of savory recipes.
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