Diabetic 2

[Lightingthunder2]

I have now become diabetic 2 which I was told is anothor medical condition coeliacs can have.Ive been a coeliac for 15 years .I feel weak all the time I test my blood sugars every day.Im on medformin .Does any one has feel so weak that has coeliac and has. become diabetic 2?

[trents]

There is no established connection between type 2 diabetes and celiac disease. There is a connection with type 1, however, as about 6% of those with type 1 diabetes also have celiac disease. This rate is 6x that of the celiac rate found in the general population. https://celiac.org/about-celiac-disease/related-conditions/diabetes-and-celiac-disease/

[knitty kitty]

Hello, @Lightingthunder2,

I understand how confusing Celiac can be, especially when one develops other health problems.

I developed Type Two Diabetes and was prescribed Metformin.  I started feeling weak and tired.  I searched for answers using my nutrition and microbiology education to find answers.  

I learned that Metformin can cause Thiamin Vitamin B1 deficiency.  Metformin blocks the thiamin transporters that allow thiamin to enter cells.  

Keep in mind that Celiac Disease causes poor absorption of all nutrients, vitamins and minerals that our bodies require daily to live.  Thiamin can be rapidly depleted because it cannot be stored for very long (3 - 21 days).  With Metformin blocking entry into cells and malabsorption from celiac disease, thiamine deficiency can set in quickly.  The early symptoms of thiamine insufficiency can be vague and easily be attributed to other things, like a bad day at work, and doctors can easily overlook the symptoms.  Doctors aren't well educated in nutritional deficiencies.  My doctors were clueless.  

I took thiamin in the form Benfotiamine and followed the Autoimmune Paleo diet (developed by Dr. Sarah Ballentyne, a Celiac herself).  Benfotiamine has been shown to promote intestinal healing.  The Paleo diet cuts out most high carbohydrate foods.  This helps me keep my blood glucose levels under control without Metformin or other medications.  Now, I do add in occasionally rice or potatoes.  I avoid most gluten free processed foods since they are not enriched with vitamins like gluten containing products and are filled with saturated fats.  I do not take any pharmaceuticals for high blood glucose.  I control my type two diabetes with diet, and take Benfotiamine.

Thiamine deficiency is found in both Type One and Type Two Diabetes.  Thiamin is not properly reabsorbed in the kidneys in both types.  Since thiamin is water soluble, it is lost easily in urine.  Type One Diabetes has a genetic component which involves thiamine transporters in cells not functioning properly due to faulty genetic information.  Type Two Diabetes may result as a consequence of thiamine insufficiency.  Ninety-eight percent of diabetics in both types are Thiamin deficient.  

Discuss with your doctor and Nutrutionist any dietary changes and supplementing with essential vitamins and minerals while you are healing.

Here are some articles I found helpful. 

Thiamine and diabetes: back to the future?

https://pmc.ncbi.nlm.nih.gov/articles/PMC8505293/

The potential role of thiamine (vitamin B1) in diabetic complications

https://pubmed.ncbi.nlm.nih.gov/18220605/

Thiamine Level in Type I and Type II Diabetes Mellitus Patients: A Comparative Study Focusing on Hematological and Biochemical Evaluations

https://pubmed.ncbi.nlm.nih.gov/32528766/

Exploring the link between dietary thiamine and type 2 diabetes mellitus risk in US adults aged 45 years and older: Insights from a cross-sectional investigation

https://pubmed.ncbi.nlm.nih.gov/39642136/

Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3)

https://pubmed.ncbi.nlm.nih.gov/26528626/

 

Edited January 7, 2025 by knitty kitty
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