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Will My Test Be Accurate?

danem

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danem Newbie
danem
Posted

So I was diagnosed with crohns a short while back, but a recent test showed i dont have it. In any case I want to be tested for Celiac because it would not require the awful drugs i take now and i fit every symtom. My question is...I have been on Methotrexate for about 2 months and I wonder if that will give a false neg. result. I am going through the same doc so I would assume he wouldnt have me get the test for no reason, but just wanted your takes. Also, I didnt eat any gluten yesterday, but have up until then and did today. Test is tomorrow. Thanks.

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Lisa Mentor
Lisa
Posted
So I was diagnosed with crohns a short while back, but a recent test showed i dont have it. In any case I want to be tested for Celiac because it would not require the awful drugs i take now and i fit every symtom. My question is...I have been on Methotrexate for about 2 months and I wonder if that will give a false neg. result. I am going through the same doc so I would assume he wouldnt have me get the test for no reason, but just wanted your takes. Also, I didnt eat any gluten yesterday, but have up until then and did today. Test is tomorrow. Thanks.

Welcome to this site!

I am not sure whether certain drugs could effect the Celiac Panel Blood Test. I do know that the blood test is not 100% reliable. The blood test can rule Celiac in, but it cann't rule it out.

Continue to eat gluten up until your testing is satisfied, it may alter your results if you are gluten free. Here are the tests that you doctor should order:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level

I hope you find your answers.

MDRB Explorer
MDRB
Posted

I would ask your doctor about the medication as he may have overlooked it (doctors are still human and as such often make mistakes).

Some doctors argue that the only way to diagnose celiacs is with an endoscopy.

Before I was diagnosed, my blood tests came back negative. My doctor told be that I definitely did not have celiacs. I then did a bit of research on the internet and found out that blood test are often inaccurate. I went back to my doctor and demanded nothing less than the most accurate test available. My endoscopy confirmed celiacs that could have gone undiagnosed and resulted it bowel cancer later in life.

Before an endoscopy you would have to eat at least one meal a day containing gluten for about a month (or it can be done straight away if gluten is a part of your usual diet) and then go into the hospital for the procedure (no picnic but not as scary as it sounds).

Blood test are not always accurate but the endoscopy results should eliminate any doubt.

Good luck :) demand the best care from your doctor!

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