My pot roast:
I don't like adding a bunch of liquid so I choose a crockpot where the meat fits snugly. I usually use my 3-quart crockpot because I try to get a smallish chuck roast. Brown the meat in a skillet if you have time. Put the roast in the crockpot and pour in a little red wine so it comes to the top of the roast. If the roast fits snugly in the crockpot this will not be more than 1/2 cup. Salt and pepper to taste. Sprinkle on 1/2t dried savory and two cloves of minced garlic. On top of that, layer a package of sliced mushrooms and a small sliced onion. They will be high and dry but don't worry - the onions and mushrooms will eventually cook down onto the roast and flavor it. Turn on the crockpot, 4-5h on high or 8h on low. If you want to thicken the juices, stir in a tsp of arrowroot starch dissolved in a little cold water an hour before serving. Enjoy!
Source: Best Pot Roast Recipes?