Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate
  • Record is Archived

    This article is now archived and is closed to further replies.

    Jefferson Adams
    Jefferson Adams

    Celiac Disease found in 4% of Adult Acetylcholine Receptor Antibody Positive Myasthenia Gravis

    Reviewed and edited by a celiac disease expert.

    Celiac.com 11/22/2009 - Celiac disease has been associated with numerous other auto-immune disorders. Recently, there appeared the case of a 40-yr-old competitive strongman with celiac disease, who responded to a gluten-free diet, but developed profound and generalized motor weakness with acetylcholine receptor antibody positive myasthenia gravis, a disorder reported to occur in about 1 in 5000 people.

    A team of researchers set out to further explore this possible relationship between myasthenia gravis and celiac disease via serological study.

    Celiac.com Sponsor (A12):
    The research team was made up of Hugh J Freeman, Helen R Gillett, Peter M Gillett, Joel Oger of the Department of Medicine (Gastroenterology and Neurology) at Canada's University of British Columbia.

    The researchers performed celiac disease screens on frozen stored serum samples from 23 acetylcholine receptor antibody positive myasthenia gravis patients with no intestinal
    symptoms.

    They examined both endomysial and tissue transglutaminase antibodies. One in 23 samples (or, about 4.3%) tested positive for both IgA-endomysial and IgA tissue transglutaminase antibodies. Subsequent endoscopic study showed duodenal mucosal scalloping, while biopsies confirmed the histopathological changes of celiac disease. 

    From this, they concluded that celiac disease and myasthenia gravis may occur together more often than is currently understood. Muscle weakness in celiac disease may be a sign of possible occult myasthenia gravis, even in the absence of intestinal symptoms.

    Source:
    Open Original Shared Link



    User Feedback

    Recommended Comments

    Guest Sydney

    I also have MG and developed celiacs later on. And, I might add, a few more auto immune challenges!

    Link to comment
    Share on other sites
    Guest LARA

    I am 52, and I have a Celiac disease, which was diagnosed 2 years ago.

    My mother had MG and Thymoma, she passed away at 68 years of age, after fighting it for 8 years. We had no idea about Celiac disease at that time. After reading this article, I may only suspect (considering my Celiac condition), that most likely she had Celiac as well.

    Link to comment
    Share on other sites
    Guest kimberly

    Posted

    I am 52, and I have a Celiac disease, which was diagnosed 2 years ago.

    My mother had MG and Thymoma, she passed away at 68 years of age, after fighting it for 8 years. We had no idea about Celiac disease at that time. After reading this article, I may only suspect (considering my Celiac condition), that most likely she had Celiac as well.

    My father recently died from M.G. I am having some symptoms of celiac disease also. Am curious if they are related.

    Link to comment
    Share on other sites
    Guest Kari

    Posted

    I was diagnosed with Celiac two years ago and MG a year ago. In addition, I was diagnosed with Hashimoto's and thyroid cancer six months ago. I definitely believe all of these things are related and am glad the scientists are looking into it also.

    Link to comment
    Share on other sites
    Guest Christopher Paietta

    Posted

    I was diagnosed with celiac disease, and immediately started a gluten-free diet, which was not very effective, for several years. After a few years I was diagnosed with Myasthenia Gravis, and it wasn't until I started the MG treatment, that the gluten-free diet became fully effective. They were obviously indirectly affecting each other.

    Link to comment
    Share on other sites


    Guest
    This is now closed for further comments

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - knitty kitty replied to glucel's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      3

      abnormal weight loss

    2. - knitty kitty replied to Neat1's topic in Introduce Yourself / Share Stuff
      7

      Maybe celiac, maybe just ncgs?

    3. - knitty kitty replied to Sarah Grace's topic in Related Issues & Disorders
      5

      Sarah Grace

    4. - trents replied to Neat1's topic in Introduce Yourself / Share Stuff
      7

      Maybe celiac, maybe just ncgs?

    5. - trents replied to Neat1's topic in Introduce Yourself / Share Stuff
      7

      Maybe celiac, maybe just ncgs?


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      125,075
    • Most Online (within 30 mins)
      7,748

    Connie Conner
    Newest Member
    Connie Conner
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.8k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):




  • Who's Online (See full list)


  • Celiac.com Sponsor (A21):



  • Popular Now

    • Neat1
      7
    • Sarah Grace
      5
    • Drewy
      6
    • Richwhitelady
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...