"Vaccine" for Celiac Disease

I think this is one of several exciting research projects that I'm hopeful can improve the lives of those with celiac disease. I suspect if you had the choice of knowing you could take a vaccine that would improve your next 70 years with celiac than you would have a different perspective. 

I don’t believe you should be calling this a vaccine, with or without quotes. Celiac disease shots should suffice. Allergy shots are not called vaccines and neither should this. It is not a vaccine why complicate the message. 

You know. I have lost trust of anything I read on this site. The info given doesn't seem to be substantiated and it seems opinions override the content. I am so hopeful for this long-running website to get their facts and acts together. I am continually disappointed.

Celiac disease is not an allergy.

Yes, but the vaccine in development is using this approach to desensitize celiacs so they will not have the autoimmune reaction to gluten/gliadin.

If they are using tiny amounts of gliadin twice a week for 4 months in the injections, I would imagine the person receiving this would feel very sick after weeks of this. Not a trial I would sign up for. I got allergy desensitization injections as a kid. My arm would swell like a baseball if the dose was too high. I wouldn't want a similar experience with gluten.

It would be more accurate to call Nexvax2 immunotherapy.  While I share your concern about the long term safety of Nexvax2, please distinguish between opinion and fact.  A significant subgroup of Celiac patients do not improve on a gluten free diet.  And, a significant subgroup of pediatric Celiac patients appear to respond to a gluten free diet (symptom resolution and negative antibodies) but still show evidence of active disease upon endoscopic evaluation.  Your experience is your experience.

From the article I can’t assess the purpose of the shots: are they to protect from incidental gluten exposure or can one eat normally, disregarding gluten?  

Assuming that the shots are reasonably free from unacceptable side-effects and risk, I’d get them even if it only meant that once a month I could have pizza and beer or an Italian meal with bread and a gluten-containing entree.

I have been gluten free for 8 years. I applaud work in this field. I rely a lot on rice and I worry about the possible buildup of arsenic found in rice - especially American grown rice. Having the ability to eat gluten to vary my diet would be great.

I would try it if mean could eat fish and chip again and birthday cakes and Piza I dispoint can't have pasta on prescription now. I very disappointed it been noughting but row in my family

Perhaps it would be more accurate to say that vaccinations do not equal immunity since in the common parlance (CDC included) vaccine and immunization are used synonymously.  

I was astonished by your comment that you would not consider a vaccine so you would not have to worry about hidden gluten.  Hidden gluten is becoming a huge issue and making many of our lives miserable as we try to stay on a gluten free diet.  The children and adults and their symptomology mentioned early in the article surely are well worth a vaccine/shot series should it be as safe as can be otherwise.

Guest Daisy - You are unnecessarily restricting yourself. There are tons of gluten-free flour mixes, cake mixes, pasta, and pizzas on the market. Yes, they are spendy, but many makers offer coupons online. Many recipes I use for quick breads and cakes adapt very well to substituting gluten-free flour blend for all-purpose flour. Experimentation with your own favorites is needed. Best hint ever to counteract the dryness/crumbles of baked goods from a chef I know who has experience with gluten-free food prep: add a big blob of sour cream. Made the best ever cobbler topping! You are limited only by your imagination. I have gifted cakes and cookies to friends and neighbors and they are always shocked when I tell them "It's gluten free." You don't have to wait for a medical treatment to enjoy your life now. I control my Celiac, it does not control me.