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KVD

Update - More Results

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In my last message (Dec. 2), I posted the results of my blood test for everyone's review. Below is my Enterolab dx followed by the blood tests that I previously posted. I had the biopsy done yesterday, so that is the only test result I am still waiting for. What the Enterolab dx tells me is that the biopsy should be negative (as my doc believes). If positive, then I'll be incredibly confused as to who is correct (or I fall in the 1% category!). As the below dx explains, I do not have the celiac genes, so I assume that I'll never develop celiac, however I do have gluten sensitivity....and milk sensitivity. Let me know if you have any comments, or use the info to compare to your own situtaion. I will post the biopsy result when I receive it. And if Enterolab is reading, thank you!

Final Laboratory Report

Gluten Sensitivity Stool Test

Fecal Antigliadin IgA 18 Units (Negative <10 Units)

Stool Test for Autoimmune Reaction to Tissue Transglutaminase

Fecal Antitissue Transglutaminase IgA 12 Units (Negative <10 Units)

Stool Test for Small Intestinal Malabsorption

Microscopic Fecal Fat Score: 559 Units (Negative < 300 Units)

Stool Test for Dietary Yeast Sensitivity

Fecal Anti-Saccharomyces cerevisiae IgA 8 Units (Normal <10 Units)

Stool Test for Milk Sensitivity

Fecal anti-casein IgA antibody 14 Units (Normal <10 Units)

Stool Test for Egg Sensitivity

Fecal anti-ovalbumin IgA antibody 7 Units (Normal <10 Units)

Gene Test for Gluten Sensitivity

Molecular analysis: HLA-DQB1*0603, 0602

Serologic equivalent: HLA-DQ 1,1 (Subtype 6,6)

Interpretation: Analysis of this stool sample indicates you have dietary

gluten sensitivity, resulting in an associated autoimmune reaction to the

human enzyme tissue transglutaminase and an increased amount of dietary fat

in the stool likely due to small intestinal malabsorption/damage. You also

have antibodies to the main cow's milk protein, casein, and hence, you are

immunologically sensitive to these foods. Levels of intestinal IgA

antibodies to dietary yeast, and chicken eggs were just below the upper

limit of normal, hence, there is no direct evidence of immunologic

sensitivity to these foods.

Although you do not possess the main genes predisposing to celiac sprue

(HLA-DQ2 or HLA-DQ8), HLA gene analysis reveals that you have a gene that

predisposes to gluten sensitivity (HLA-DQ1 involving the DQB1*0602 subtype).

For optimal health and prevention of small intestinal damage, osteoporosis,

damage to other tissues (like nerves, joints, pancreas, skin, liver, among

others), and malnutrition, recommend a strict gluten free diet and

re-testing in one year to insure this reaction is lessening. If you are

experiencing any symptoms, these may resolve following a gluten free diet.

Since antibodies to cow's milk are found with a greater frequency in gluten

sensitive individuals and people with certain autoimmune diseases, removal

of these foods from your diet may benefit you directly, as well as add to

the benefits of a gluten-free diet (if you avoid gluten).

As gluten sensitivity is a genetic syndrome, you may want to have your

relatives screened as well.

Blood test from prior posting:

1) Gliadin AB (IGG, IGA); tTG IGA, Tissue Transglutaminase AB IGA: 5

2) Gliadin AB IGG: 65 H

3) Gliadin AB IGA: 12

Also, what are these other two test:

1) Anti-nuclear AB W/RFX, Anti-nuclear AB, EIA: POSITIVE

2) Anti-nuclear AB Titer-Pattern, Anti-nuclear AB Titer: 1:80

KVD

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Guest sriddle78

KVD,

I am looking at getting the tests from EnteroLab. Which panel did you get? I noticed you had the yeast and egg test as well...are those separate from the $349 set of tests?

Thank you,

Shannon :)

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Hi Shannon-

Yes, the yeast and egg tests are separate and cost an additional amount. I bought the set of tests you referred to (for gluten) plus the yeast and egg tests. I don't recall what they cost, but it's posted on their website.

KVD

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I have just gotten back results from Enterolab for my daughter saying that she has two HLA DQ1 subtype 6 genes. I am confused about what this means. She showed intestinal damage, as well as gluten sensitivity.

I don't understand the difference between the DQ2, DQ8 and DQ1 genes. Can anyone help me with the difference? I don't understand the difference between celiac sprue and gluten sensitivity. I thought celiac sprue was gluten sensitivity.

As you can tell, I am very new to this.

Thanks,

Suse5

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Celiac sprue is the classic intestinal damage - flattened villi. Gluten sensitivity is where your body reacts to gluten in one or more presentation. All people with celiac sprue are gluten sensitive, but not all gluten sensitive have celiac sprue. Gluten sensitivity alone might present in other ways. See the list on this site of the many "symptoms" people exhibit.

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