Test Results - Care To Clarify?

[jahknow41]

Hi all,

26 year old guy here...recently underwent testing for Celiac Disease after some gastrointestinal issues that appeared out of nowhere six weeks ago, and are seemingly lingering. Very new to all of this, and am slightly confused regarding some recent bloodwork of mine. Here are my results..

Deamidated Gliadin Abs, IgA - 3.2 (Range: 0-10)

Deamidated Gliadin Abs, IgG - 0.8 (Range: 0-10)

t-Transglutaminase (tTG) IgA - 1 (Range: 0-3: Negative; 4-10: Weak Positive; >10: Positive.)

t-Transglutaminase (tTG) IgG - 1 (Range: 0-5: Negative; 6-9: Weak Positive; >9: Positive.)

Endomysial Antibody IgA - Negative

Immunoglobulin A, Qn, Serum - 475 (Range: 70-400)

My only out of range test was my final one (Immunoglobulin A, Qn, Serum), which tested positive rather than negative. Through my research, I've learned that a deficient reading here negates other testing...but what does a positive reading indiciate?

Knowledgeable Celiacs out there....what are your thoughts?

[ravenwoodglass]

First off false negatives are not uncommon. If you have only been ill for 6 weeks that may not be long enough for the antibodies to have built up enough or you may be one of the many who wouldn't show positive on the blood test even when close to dieing. I am one of the latter.

Are you scheduled for an endoscopy? If you are keep eating gluten until that is done. If the doctors are basically saying nope you in the clear and won't do furthur testing then you can simply try the diet and see if it helps. Another option is to go with Enterolab. They do stool testing for antibodies and while they cannot diagnose you with celiac they can tell you if the antibodies are present.

One other thing, have they done stool samples at the doctors to check to make sure you don't have any form of food poisoning or some other issue that is causing problems? If your illness came on suddenly that would be something that should be done.

[jahknow41]

Hi all,

26 year old guy here...recently underwent testing for Celiac Disease after some gastrointestinal issues that appeared out of nowhere six weeks ago, and are seemingly lingering. Very new to all of this, and am slightly confused regarding some recent bloodwork of mine. Here are my results..

Deamidated Gliadin Abs, IgA - 3.2 (Range: 0-10)

Deamidated Gliadin Abs, IgG - 0.8 (Range: 0-10)

t-Transglutaminase (tTG) IgA - 1 (Range: 0-3: Negative; 4-10: Weak Positive; >10: Positive.)

t-Transglutaminase (tTG) IgG - 1 (Range: 0-5: Negative; 6-9: Weak Positive; >9: Positive.)

Endomysial Antibody IgA - Negative

Immunoglobulin A, Qn, Serum - 475 (Range: 70-400)

My only out of range test was my final one (Immunoglobulin A, Qn, Serum), which tested positive rather than negative. Through my research, I've learned that a deficient reading here negates other testing...but what does a positive reading indiciate?

Knowledgeable Celiacs out there....what are your thoughts?

Thank you for the input. I understand that blood tests are not always fool-proof, and false negatives can occur. Specifically, can anyone please clarify my results and the reasoning/correlation behind the positive Immunoglobulin A, Qn, Serum?

[laurelfla]

If anyone can shed some light on this I would so appreciate it - my uncle has the same situation. Now he has been on the diet three weeks, with no changes. He also has scleroderma and has been through chemo, so there are clearly other health issues, but his doctor has been so unhelpful that I would really appreciate it if anyone could chime in about the immunoglobulin A. Btw, his report's normal ranges for this test were something like 61-356 and his number was 731. Thanks!!

[Lisa]

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