Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Celiac.com!
    eNewsletter
    Donate

Mixed test results

Tbymommy

Recommended Posts

Tbymommy Newbie
Tbymommy
Posted

Hi.

My ten year old was ordered the celiac testing, along with other tests, due to lack of growth. Within the celiac blood panel some tests came back negative and some positive. 

The deiamidated giadin test came back positive but the other tests came back negative. He is being referr d to a GI for a biopsy. 

Can he have celiac with only one positive and is it likely he does? There is a wait time for the biopsy so I'm sitting and waiting to see anxiously!

 

 

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


cyclinglady Grand Master
cyclinglady
Posted
2 hours ago, Tbymommy said:

Hi.

My ten year old was ordered the celiac testing, along with other tests, due to lack of growth. Within the celiac blood panel some tests came back negative and some positive. 

The deiamidated giadin test came back positive but the other tests came back negative. He is being referr d to a GI for a biopsy. 

Can he have celiac with only one positive and is it likely he does? There is a wait time for the biopsy so I'm sitting and waiting to see anxiously!

 

 

Welcome!  I am sorry that your son is ill!   Yes, you can have celiac disease with only one positive in the panel.  That happened to me.  I had only a positive on just the DGP IgA.  It was not a fluke.  I test this way even in follow-up testing.  Biopsies revealed intestinal damage ☹️.  

Open Original Shared Link

This kind of result does happen among the very young or very old (and some people in between).  While not common, it is possible.  You need to see a GI.  For some it can be a while.  In that case, keep checking for appointment cancellations.  

Before an endoscopy he must be consuming a gluten diet for 2 to 4 weeks prior.  I would hate for a kid to have to wait.  Again, see what you can do to expedit the appointment.  

In the meantime, learn all you can about celiac disease.  Anyone else with autoimmune disease in your family?  They should consider testing too.  

Link to comment
Share on other sites
Tbymommy Newbie
Tbymommy
  • Author
Posted

So I have another son with a different autoimmune disorder (jia). But my brother has type one diabetes which I've read is gene related to celiac. I myself have been tested for celiac twice because I have gastro issues with it but it has always been negative. 

Yes they said it may be while. Hoping it's not too long!

Link to comment
Share on other sites
cyclinglady Grand Master
cyclinglady
Posted

You should confirm that you were given the entire celiac panel.  It is still common for most doctors to use the screening TTG and then check for an IgA deficiency (cheap, effective but does not catch all celiacs) .    What if you test like your child?  What if you are a seronegative celiac (occurs in 10% of celiacs)?  

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      121,195
    • Most Online (within 30 mins)
      7,748
    Marianne Davis
    Newest Member
    Marianne Davis
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Isolated DPG-Iga

      By trents · Posted

      From the article I linked above: DGP-IgA and DGP-IgG (Deamidated Gliadin Peptide) Blood Tests for Celiac Disease These tests measure the levels of antibodies in the blood, but specifically targets deamidated gliadin peptides, which are a type of gluten protein that can trigger an immune response in people with celiac disease. The test is not always included in adults, but should be in cases with IgA deficiency.  I'm not sure if this is a grammatical error or not but in the context, two tests are being spoken of together so it could be intended to say, "These tests". I'll ask Scott about that.
    • Kmd2024
      Isolated DPG-Iga

      By Kmd2024 · Posted

      No they did not run a total IGA. But wouldn’t the DPG-IGA also be negative also if I was IGA deficient? They did also run a TTG-IGG and a DPG-IGG and they were also negative.
    • trents
      Isolated DPG-Iga

      By trents · Posted

      The DGP-IGA is valuable when celiac is suspected but the person being tested is IGA deficient. Were you tested for IGA deficiency. In other words, was there a test known as "Total IGA" ordered? Here is an overview of the various blood tests that can be run when diagnosing celiac disease:   
    • Kmd2024
      Isolated DPG-Iga

      By Kmd2024 · Posted

      Has anyone ever negative blood work except for the DPG-IGA? Mine was 42 (reference range negative is >20. The TTG iga was negative. I have always suffered from bad gas issues and lately have been having bouts of diarrhea and constipation. I also have a bumpy rash that comes and goes below both elbows. i have an endoscopy scheduled in May but I was just wondering if anyone else had bloodwork like this and what was the end result?
    • trents
      Constant low back, abdominal and pelvic pain!

      By trents · Posted

      Welcome to he forum community, @DjinnDjab! You wrote: "i just found out i may have celiac. so needless to say i no longer have friends or relationships." Are you saying that the need to eat gluten free has resulted in losing all your friends and your entire social life?
×
×
  • Create New...