Celiac.com Sponsor (A1):



Celiac.com Sponsor (A1):


0
Deltalady

Test Results

Rate this topic

Recommended Posts

What does this result mean exactly?  

Endomysial Abs, IgA Negative   Negative
Transglutaminase IgA <2 U/mL 0 - 3 U/mL
Negative 0 - 3
Weak Positive 4 - 10
Positive >10
Tissue Transglutaminase (tTG) has been identified
as the endomysial antigen. Studies have demonstr-
ated that endomysial IgA antibodies have over 99%
specificity for gluten sensitive enteropathy.
Immunoglobulin A (IgA) 518 mg/dL 87 - 352 mg/dL

Share this post


Link to post
Share on other sites

Join eNewsletter


Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8):


Hi,  I just wanted to add some insight to my question on the test results.  I am 58 experiencing stress fractors to the foot without any extra activity.  I have osteoporosis and the thought process of the doctors is that I have another cause besides age for the osteoporosis.  The foot is not healing after 11 weeks in a boot.  Ortho sent me to Endo.  Endo did blood test.  Hormones normal and received the below results on Celiac.  I have had osteoarthritis since 21, Was diagnosised at 29 as being allergic to wheat, symptom was I lost my voice after having my first child.  Had my second at 32 and magic I could eat wheat again and not lose my voice.  Last year I was tested autoimmune because of lung issues; MAC and bronchiaestasis.  IGA was high then but no further testing.  I do not have digestion issues except lactose intolerant.  I do have low values on vitamin D. I do not go back to Endo until 2 weeks from now.  My sister is fighting her own issues which is pointing to autoimmune but drs. have figured her out yet.  My mom as MS and her mom died of ALS, Dad's side had Lupus.  Any thoughts?

Share this post


Link to post
Share on other sites

Join eNewsletter

13 hours ago, Deltalady said:

What does this result mean exactly?  

Endomysial Abs, IgA Negative   Negative
Transglutaminase IgA <2 U/mL 0 - 3 U/mL
Negative 0 - 3
Weak Positive 4 - 10
Positive >10
Tissue Transglutaminase (tTG) has been identified
as the endomysial antigen. Studies have demonstr-
ated that endomysial IgA antibodies have over 99%
specificity for gluten sensitive enteropathy.
Immunoglobulin A (IgA) 518 mg/dL 87 - 352 mg/dL

Hi Delta! 

Well, it appears that your celiac screening is negative, but that does not rule out celiac disease yet. I would ask your doctor to run the DGP IgA and DGP IGG (even though you are not IGA deficient).  Like you, I tested negative to the TTG and EMA tests, but I was positive on the DGP IgA.  My intestinal biopsies revealed a Marsh Stage IIIB.  If my GI had not ordered the entire blood  panel, my diagnosis would not have been caught.  I still continue to test this way even in follow-up blood tests.  Then there is the possibility that you are a seronegative celiac.  Some 10% are seronegative.  The GI would have to do the endoscopy to rule out celiac disease.  Learn more:

https://www.mayomedicallaboratories.com/it-mmfiles/Celiac_Disease_Diagnostic_Testing_Algorithm.pdf

My symptoms at the time of my diagnosis were anemia (no GI issues).  Two months after my diagnosis, I fractured some vertebrae doing NOTHING!  That is when I got my osteoporosis diagnosis.  I was 51 at the time.  MY IgA is also very high (over 700).  For celiac testing, it is just a control test (e.g. Does the TTG IgA test work).  As a stand alone test,   it could be something like autoimmune or excessive  inflammation.  I also have Hashimoto's Thyroiditis which was diagnosed 20 years ago.  

https://labtestsonline.org/understanding/analytes/immunoglobulins/tab/test/

Please do not settle for an aging or an "it's all in your head diagnosis".   Something is wrong.  Continue to advocate for your health!  


Non-functioning Gall bladder Removal Surgery 2005

Diagnosed via Blood Test and Endoscopy: March 2013

Hashimoto's Thyroiditis -- Stable 2014

Anemia -- Resolved

Fractures (vertebrae): June 2013

Osteopenia/osteoporosis -- June 2013

Allergies and Food Intolerances

Diabetes -- January 2014

Celiac.com - Celiac Disease Board Moderator

Share this post


Link to post
Share on other sites

Join eNewsletter

Oh...are you a smoker?  That can slow down healing.  


Non-functioning Gall bladder Removal Surgery 2005

Diagnosed via Blood Test and Endoscopy: March 2013

Hashimoto's Thyroiditis -- Stable 2014

Anemia -- Resolved

Fractures (vertebrae): June 2013

Osteopenia/osteoporosis -- June 2013

Allergies and Food Intolerances

Diabetes -- January 2014

Celiac.com - Celiac Disease Board Moderator

Share this post


Link to post
Share on other sites

Join eNewsletter

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

0


Join eNewsletter