Jump to content
  • You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Blood test results - levels of ttg iga


En0u1209

Recommended Posts

En0u1209 Rookie

Hi, 

I have received positive blood test results and was just wondering about ranges.  

My results were 13. The range appears to be 4-10 weakly positive and over 10 positive. From this, I thought my results were pretty indicative of celiac disease. Looking online a lot of people seem to have results in the hundreds. My dr also described them as ‘modest’. On that basis, my results don’t seem that high and may not mean celiac. I’m waiting for an endoscopy so will have a final diagnosis soon. I appreciate people can’t predict the outcome. I was just interested what people thought and if people had similar levels and then a diagnosis. 

Thanks in advance


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



GFinDC Veteran

Hi,

You didn't say what kind of test you had done.  The test was probably the ttg IgA.  That is often used as a screening test.  However it is only one of the type of antibody reactions that they can use to test for celiac disease.  The fulll celiac panel would also have the DGP IgA, DGP IgG, EMA, and total serum IgA antibody tests.

Some more info:  https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/

En0u1209 Rookie

Hi, yes it was the ttg IGA. Thank you for your response. X

cyclinglady Grand Master

A slightly elevated TTG could be something other than celiac disease (like another autoimmune like Crohn’s), but many members have barely elevated numbers and yet have severe small intestinal damage.  

I never even had an elevated TTG even on follow-up testing (only the DGP IgA) and I had moderate to severe patches.  Go figure!  

Keep eating gluten until you get your endoscopy this is critical!  

  • 3 weeks later...
En0u1209 Rookie

Just as an update, for anyone searching a similar issue. I have now had my Celiac diagnosis following a positive biopsy result.

Interestingly, my follow-up bloods, which were done at the same time as the endoscopy, had a TTG-IGA level of 147. My Dr suspects I hadn't been consuming enough gluten before the first test. 

cyclinglady Grand Master

Thanks for sharing!  Your comments may very well help someone else.  ?

  • 4 weeks later...
Keight Enthusiast

Wow! Thanks for all that, OP. I had two panels done, but without my paperwork here, I cannot tell you what they were; deaminated gliaden IGG or IGA and another with IgG or IGA. One was 110 and the other 70- something. It has me a wee bit anxious that, either, they are false positives, or, I might have a fair bit of damage. 

 

If it isn't Coeliac, what on earth has me have very low vit and mineral levels?! 


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



cyclinglady Grand Master
4 hours ago, Keight said:

Wow! Thanks for all that, OP. I had two panels done, but without my paperwork here, I cannot tell you what they were; deaminated gliaden IGG or IGA and another with IgG or IGA. One was 110 and the other 70- something. It has me a wee bit anxious that, either, they are false positives, or, I might have a fair bit of damage. 

 

If it isn't Coeliac, what on earth has me have very low vit and mineral levels?! 

The DGP tests are very specific.  They are probably not false positives. I had plenty of damage, but the gluten free diet healed my small intestine.  No sense worrying about other possible illnesses that could cause intestinal damage. Focus on  one issue at a time.  Right now, celiac disease seems like the most obvious diagnosis.  

It can be very hard to wait for the endoscopy.  Take this time to eat all your old gluteny favorites.  That is what I did!  No sense just consuming  some old boring bread!  

Keight Enthusiast

Lol. Agreed, cyclinglady. You sensible person, you!

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - glucel replied to glucel's topic in Super Sensitive People
      18

      iron digestibility

    2. - knitty kitty replied to glucel's topic in Super Sensitive People
      18

      iron digestibility

    3. - glucel replied to glucel's topic in Super Sensitive People
      18

      iron digestibility

    4. - Scott Adams commented on Scott Adams's article in Latest Research
      3

      New Research Reveals How Antibody Genes May Shape the Immune Response in Celiac Disease

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      134,004
    • Most Online (within 30 mins)
      10,442

    Bothy
    Newest Member
    Bothy
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Who's Online (See full list)

    • There are no registered users currently online
  • Upcoming Events

  • Posts

    • glucel
      I ate sprouted buckwheat and hard boiled egg last night instead of cereal and got extra 1/2 hour sleep but more importantly feel better this morning. I do sleep in cycles that seems to rotate btwn 3 and 6 hrs but I will monitor next time I make a pot. Bwheat is a complete protein with good amounts of thiamin, magnesium, fiber and iron. High carb but much lower glycemic and much healthier than refined flour cereal.
    • knitty kitty
      @glucel,  There's a strong correlation between thiamine deficiency, hypoxia, and insomnia.  Thiamine is needed to help red blood cells carry oxygen.  In thiamine deficiency, hypoxia (lack of oxygen in tissues) occurs, and this can result in insomnia. Hypoxia causes systemic inflammation, increases inflammatory markers, and is associated with cardiovascular events.  Curiously, thiamine deficiency is correlated with excessive daytime sleepiness and oversleeping.   I found a combination of Tryptophan, Pyridoxine B 6, magnesium, and L-theanine works very well for inducing sleep.  Sometimes, I add Passion Flower Extract and/or Sweet Melissa.  There's no side effects the next morning with Passion Flower, it just induces sleepiness.  Sweet Melissa is groovy, and has anti-inflammatory effects on the digestive system.   I prefer to take 250 mg Benfotiamine and 100 mg Thiamine TTFD in the mornings and another dose of Benfotiamine at lunch.  I try not to take any thiamine after four p.m. because it keeps my brain so energized and wanting to think... Oh, I do take a combination of another form of thiamine (sulbutiamine), Pyridoxine and Cobalamine for a pain reliever sometimes, but I can sleep after taking that.  But thiamine does help regulate circadian rhythm.   Make sure you're getting Omega Three fats! They'll help you satisfy that late night carb craving with fewer carbs.  Flaxseed oil, olive oil, sunflower seed oil.  Nuts and nut butters, like walnuts and cashews, are good, too, if you can tolerate them.    Try taking the 100mg thiamine HCl before your aerobics and see if there's a difference.  Sweet dreams! References: Network Pharmacology Analysis of the Potential Pharmacological Mechanism of a Sleep Cocktail. ......(Skip to Section Four) https://pmc.ncbi.nlm.nih.gov/articles/PMC11201840/ Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, and Cross-Over Study https://pubmed.ncbi.nlm.nih.gov/39683592/
    • glucel
      Thanks to everybody for your help. I reread the dr's notes from the biopsy procedure and it seems I had worse than atrofied villi. It was termed flattened mucosa. So while iron ferratin levels are normal my bet is, as kitty alluded to, iron not getting into cells. I have dr appointment next mo but don't hold out a lot of hope, There is strong correlation of low red blood cells and insomnia so at least I finally solved that one after few yrs of being mislead. I intend to take stop taking 100 mg b1 at noon time and start 150 mg benfotiamin. I may or may not add the the 100 mg b1evening meal. BTW, last night had 1/3 lb beef. potato then 2 bowls cereal and an apple later in the eve. I generally do my areobics before supper so maybe that contributes to the hunger.  
    • knitty kitty
      I have osteoporosis and have crushed three vertebrae.  I supplement with Lysine, Tryptophan, threonine, calcium, Boron, Vitamins D, A, and K, and the B vitamins (folate, B12, and Thiamine B1 especially for bone health).   I tried Fosomax, but it tore up my insides.  I prefer the supplements.  I feel better and my bones feel stronger.   References: A composite protein enriched with threonine, lysine, and tryptophan improves osteoporosis by modulating the composition and metabolism of the gut microbiota https://pubmed.ncbi.nlm.nih.gov/41915427/
    • knitty kitty
      @Aileen Cregan, I was put on high blood pressure medication, too. But I was able to correct my high blood pressure by supplementing with Thiamine Vitamin B 1.  I am no longer on high blood pressure medication.  I feel much better without the medication. I continue to supplement Thiamine in the form Benfotiamine.   The particular high blood pressure medication I took was Norvasc (amlodipine), which causes thiamine deficiency by blocking thiamine transporters so that thiamine cannot enter cells.  Benfotiamine can get into cells by merging with the cell membrane, thus bypassing nonfunctional thiamine transporters.   Indapamide also blocks thiamine transporters! The use of this type of medications that block thiamine precipitated Wernickes Encephalopathy.  My doctors did not recognize the connection to Thiamine deficiency.  I nearly died.   Talk to your doctor and dietician about supplementing with Benfotiamine, a fat soluble form of thiamine that bypasses thiamine transporters.  Ask for an Erythrocyte Transketolace Activity Assay to check your thiamine levels asap.  Routine blood tests for thiamine are not an accurate measure of  thiamine in the body.   Absorption of essential vitamins like Thiamine is altered in Celiac Disease due to damaged villi, inflammation and dysbiosis.  The Gluten Free diet can be lacking in vitamins and minerals.  Discuss supplementing with all the eight B vitamins,  the four fat soluble vitamins and necessary minerals. Please keep us posted on your progress! References: Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3) https://pubmed.ncbi.nlm.nih.gov/31764942/ The Pivotal Role of Thiamine Supplementation in Counteracting Cardiometabolic Dysfunctions Associated with Thiamine Deficiency https://pmc.ncbi.nlm.nih.gov/articles/PMC11988323/
×
×
  • Create New...