What Role if Any does a Thiamine Deficiency Play in a Celiac Diagnosis or How Beri Beri can be overlooked in a Celiac Diagnosis?

[Posterboy]

To All,

This is the thread I said I would start....

This analysis/opinion will turn on the neurotransmitter Acetylcholine.

While it is well known Acetylcholine effects our CNS....it is less well know that Acetylcholine also performs the same function for the Parasympathetic Nervous System.

https://en.wikipedia.org/wiki/File:1503_Connections_of_the_Parasympathetic_Nervous_System.webp

When we get low in Thiamine and subsequently Acetylcholine we lose the ability to control our bowels because our Vagus nerve in essence short circuits....and our body no longer can control it's organs connected to the Vagus Nerve leading to bowel problems associated with Celiac disease.

IE  a Vagus Nerve disorder develops once we get low in Thiamine.....

Here is a nice over of how a Vagus nerve disorder can trigger issues with our Parasympathetic Nervous System.

https://www.md-health.com/Vagus-Nerve.html

I hope this is helpful but it is not medical advise.

Posterboy,

[knitty kitty]

Thanks, Posterboy, for starting a new thread about thiamine. 

I have found a video of Dr. Chandler Marrs, the coauthor with Dr. Derrick Lonsdale, of the book "Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition."  

Dr. Marrs in person explains the importance of thiamine and how thiamine deficiency is involved in disease.  

I hope this video will allow our discussion of the importance of thiamine to progress.  

https://m.youtube.com/watch?v=BkKmiZkiEPI

Knitty Kitty

[Posterboy]

Knitty Kitty,

Thanks for that link.  I will be sure to watch it all when I get the chance.

I came across some research recently that I thought was worth sharing.

Entitled "Biomarkers for Detecting Thiamine Deficiency—Improving Confidence and Taking a Comprehensive History are also Important"

https://academic.oup.com/alcalc/article/45/2/213/135527

Showing that when Clinicians are alert they can spot symptom's of a Thiamine deficiency before Beri Beri develops.

I will quote Table 1 because I think it is very informative and helpful.

"Table 1

Clinical evaluation of patients at risk of thiamine deficiency

Clinical history 

• Weight loss in past year 

• Reduced Body Mass Index 

• General clinical impression of patient’s nutritional status 

• High dietary carbohydrate intake 

• Recurrent episodes of vomiting in past month 

• Co-occurrence of other nutritionally related conditions (polyneuropathy, amblyopia (aka Lazy Eye), pellagra, anaemia) 

 

Early signs–symptoms of thiamine deficiency 

• Loss of appetite 

• Nausea/vomiting 

• Fatigue, weakness, apathy 

• Giddiness, diplopia 

• Insomnia, anxiety, difficulty in concentration 

• Memory loss 

 

Later signs–symptoms 

• Classic triad: oculomotor abnormalities, cerebellar dysfunction (ataxia) and confusion 

• Quiet global confusion with disorientation in time/place 

• Confabulation/hallucination 

• Onset of coma 

Reproduced with permission from Practical Gastroenterology, June 2009.

a Patients may present with different combinations of symptoms and signs."

Since a patient can present with different combinations of Beri Beri it can be hard for the average medical staff to contribute an early Thiamine deficiency to only one symptom and why it is often diagnosed at a later stage.  They produced this list of symptom's to train other medical staff of it's varied presentations.

They  note quoting

"We agree that it is very important to educate all members of the clinical team to recognize the early signs and symptoms of thiamine deficiency and about the urgency of treatment."

And I couldn't agree more!  I had several of these symptom's and because I was not an Alcoholic they were All missed!

I hope this is helpful but it is not medical advise.

Posterboy,

[Posterboy]

Knitty Kitty et Al,

I will try and be brief since I said/spent to much time  in replying to this thread on Vitamins....

Posted here for anybody who wants to read it...

That low Thiamine levels can predict Sepsis.....and it would explain why approx. 50% of Celiac's could be diagnosed with Refeeding Syndrome if the doctors knew to look  for it (Electrolyte Abnormalities mainly and Chronic Fatigue)...when a Celiac is  in  Crisis (IE have Electrolyte Abnormalities) like Low Albumin levels ( a sign of Malnutrition) or Low Potassium levels....or something like elevated CRP levels etc...

https://www.sciencedirect.com/topics/nursing-and-health-professions/thiamine-deficiency

See the paragraph entitled Volume 2...

Also see this Posterboy blog post about how I had Refeeding Syndrome aka RFS with my Celiac diagnosis.....and ALL the symptom's were missed because I was not an alcoholic...

Despite having many of the "Electrolyte Abnormalities" ......a Thiamine deficiency was never considered...

I share that it might help the next person.

I hope this is helpful but it is not medical advise.

2 Tim 2:7 “Consider what I say; and the Lord give thee understanding in all things” this included.

Posterboy by the Grace of God,

[Posterboy]

To All,

I just wanted to post this nice video article on Thiamine and it's role in a healthy Vagus nerve I came across recently.  If you have time to watch it all (it is a little over an hour)....I think it will help you see how taking Befotiamine can help many of your GI issues....because your GI motility will improve from a better functioning Vagus nerve....it should be noted stimulating the vagus nerve....is an FDA acceptable medical procedure....so the benefits are proven....but I think taking a Vitamin is a better, much safer way to do it!

It is entitled "Is Thiamine Deficiency Destroying Your Digestive Health? Why B1 Is ESSENTIAL For Gut Function"

 

If  your preference is to read rather than watch things....then see article on "How Low Thiamine Can Thin Villi Old Research rediscovered and its clinical significance in Celiac disease.

I hope this is helpful but it is not medical advise.

Posterboy,

[Posterboy]

To All,

 I just wanted to add this Posterboy blog post to this thread because it seems like they go together.

I hope it helps the someone else who finds this thread in the future...

If Fatigue is a problem for you then taking Magnesium Citrate/Glycinate and Benfotiamine will help your fatigue symptom's.

I know I have been you!

I hope this is helpful but it is not medical advise.

Posterboy,