Time of day for TTG blood test

[eekunique]

Do you know if time of day makes any difference to the TTG blood test? And what about whether you've eaten that day?

I only ask as I'm also getting my TSH tested and I know it's important to do this first thing in the morning before eating.  

Thanks. 

[Scott Adams]

It should not make a difference what time of day it is, but you do need to be on a gluten challenge before the test.

Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy:

Quote

"...in order to properly diagnose celiac disease based on serology and duodenal histology, doctors need patients to be on gluten-containing diets, even if they are causing symptoms, and this is called a "gluten challenge."

• Eat gluten prior to celiac disease blood tests: The amount and length of time can vary, but is somewhere between 2 slices of wheat bread daily for 6-8 weeks and 1/2 slice of wheat bread or 1 wheat cracker for 12 weeks 12 weeks;
• Eat gluten prior to the endoscopic biopsy procedure: 2 slices of wheat bread daily for at least 2 weeks;

and this recent study recommends 4-6 slices of wheat bread per day:

 

 

[eekunique]

6 hours ago, Scott Adams said:

4-6 slices of wheat bread per day:

Thank you. The most I'm managing is 3 and it's awful!! 

[Scott Adams]

3 should be plenty...I think the recommendation is at least 2 slices per day. I'm sorry you need to go through this, but if you already know you have issues with gluten, will the test results, even if they might turn out to be negative for celiac disease, cause you to continue eating gluten afterwards?

Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.