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Recently tested, could anyone tell me what my results mean?


Amiee
Go to solution Solved by Scott Adams,

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Amiee Newbie

So I recently got tested for celiac due to constant stomach pain and nausea. My grandmother has it so we thought it best to check and apparently it’s positive. I was just hoping someone could explain what this means, thank you!!

Deamidated gliadin peptide IgG   11. FLU.   (<5)

Total IgA    2.90.  g/L   (0.40-3.50)

Transglutaminase IgA   27. FLU.   (<5)


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trents Grand Master
(edited)

Welcome to the forum, @Amiee!

Total IGA is not a celiac disease antibody test per se. However, if total IGA is low, then it can cause false negatives in the actual IGA celiac antibody tests.

The Transglutaminase IgA is a celiac antibody test and it is positive in your case, indicating you do have celiac disease. Anything over 5 FLU would be positive. It is not strongly positive and since there are other factors that can cause elevated Transglutaminase IgA, it is likely that you will be referred to a GI doc for an endoscopy with biopsy of the small bowel lining to confirm the result of the antibody testing. Celiac disease damages the lining of the small bowel and the biopsy is considered to be the gold standard of diagnostic procedure for determining celiac disease. 

Edited by trents
  • Solution
Scott Adams Grand Master

It looks like you have 2 positive tests for celiac disease, your Transglutaminase IgA is over 5x the cut off for celiac disease (some doctors may diagnose you just by this and the fact that it runs in your family), and your Deamidated gliadin peptide IgG is ~2x above the level.

This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. 

 

 

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