I Need Help With My Daughters Test Results Please!

[3groovygirls]

My 3 year old DD was tested for Celiacs awhile ago, her Dr. said it was negative. Because of some other health issues we had to get her ENTIRE Children's Hospital file and I'm looking at her Celiacs results and I don't get it. I'm particularly curious b/c now her little sister seems to have a total classic gluten intolerance and can't have it at all. Since it's genetic, it has me wondering.

I'm reading the results and don't "get it", could someone explain this?

Her IgA value is 0.4 U/ML it says the Ref. Range is <4.0 U/ml

Her IgE is 16, ref range <33

Her PAB (Prealbumin) is 20.9, range 9.6-32

So is the reference range what WOULD be Celiacs or what is not? Either way she either misses one or 2. Can anyone shed some light on this for me? I looked online but can't seem to make sense of that either! Thanks!

LInda

[happygirl]

These aren't the tests that should be run for Celiac.

These are the tests:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

[3groovygirls]

Well, crud! So her GI ran the wrong tests??? I was wondering where the IGG was. There is no mention of any of that.

These aren't the tests that should be run for Celiac.

These are the tests:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

[fedora]

Can you be more specific on the IgA test? Is it total IgA, anti-gliadin IgA, anti-tTg IgA? Without this info it is hard to figure out what you mean. An IgE reaction is a traditional allergy reaction. You can be negative with an IgE reaction and still have Celiac. Celiac is an intolerance. Different antibodies are involved. I do not know what PAB is.

Blood test can give false negative. Your daughter could be celiac. some people test through enterolab others just do the gluten free diet. You could try retesting her or testing her sister. You say her sister can't have gluten. Sounds likely that she can't either. You could list their symptoms. good luck

[3groovygirls]

Ok, the IgA says it was Anti-Human Tissue Transglutaminase IgA ELSIA, that was 0.4 U/ml

All the IgE says is IgE, I can't find and IgG value anywhere!

Originally she had FTT but then this was negative so they just had me pack her with calories, etc. She never has diarrhea, but she does have chronic constipation, which we always thought was related to her other health issues. But now given that my infant DD is completely and totally gluten intolerant (She hasn't been tested) I wonder. With my infant, 3 cheerios and she has diarrhea, she got FTT after introducing solids, etc, etc. Removed gluten and she started sleeping through the night, not being clingy and now after being off it for a month and a half the weight is piling on! So yes, the situation with my youngest is making me requestion my middle DD and her "negative" celiacs test.

Linda

[happygirl]

It looks like you had the tTG IgA test done, which is one of the most specific for Celiac. However, the other tests, particularly the total IgA and EMA IgA should be done as well.

[ryebaby0]

How old was your daughter when the tTg was run? Until children are well past 2 yrs. , the test is notoriously unreliable. Also, was she eating gluten still when it was run?

It's possible to have one child with, and one without, so maybe she isn't celiac and it's something else.

[Nikki2003]

My daughter is now almost 4 1/2 yrs old she was disgnosed at 2 1/2 yrs old her ttg (iga) was 80 Normal at that lab was <20. She all the other celiac tests were all normal including all her rast tests for wheat and any other allergies. But her biospsy was positive also ans also showed she had gastritis and esophagitis. Has the dr suggested trying her on a gluten-free diet and seeing if it helps?

IT has helped my daughter tremendously it has taken alot of time and still is but is working.

I hope it all works out for you.