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Type 1 Diabetes


Lisa

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Lisa Mentor

Here is an interesting article regarding study tests vaccine-like therapy for Type 1 diabetes involving the immune system:

Open Original Shared Link

The article states "that scientists hope to control Type 1 diabetes by curbing the rogue immune cells that cause it. An injection revs up the subject's immune system, part of the a quest to create a vaccine-like therapy."

It goes on to state that "a "therapeutic vaccine" must shut down only the cells that erroneously attack a Type 1 diabetics, own pancreas. Body-wide immune suppression would leave patients vulnerable to other illnesses."

This sounds similar to the Celiac vaccine study in Australia.


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kenlove Rising Star

Thanks for posting this one -- forwarded it to my doc. They still cant decide if I'm 1 or 2!

Being celiac and diabetic is not fun but its better than dead!

Here is an interesting article regarding study tests vaccine-like therapy for Type 1 diabetes involving the immune system:

Open Original Shared Link

The article states "that scientists hope to control Type 1 diabetes by curbing the rogue immune cells that cause it. An injection revs up the subject's immune system, part of the a quest to create a vaccine-like therapy."

It goes on to state that "a "therapeutic vaccine" must shut down only the cells that erroneously attack a Type 1 diabetics, own pancreas. Body-wide immune suppression would leave patients vulnerable to other illnesses."

This sounds similar to the Celiac vaccine study in Australia.

neesee Apprentice
Thanks for posting this one -- forwarded it to my doc. They still cant decide if I'm 1 or 2!

Being celiac and diabetic is not fun but its better than dead!

Type 1s are usually thin at diagnosis. They can't control glucose levels with oral medications. They need insulin because their pancreas's no longer have the ability to make insulin. Type 2s do make insulin. For some reason their bodies no longer react to it. Type 1s get a condition called ketoacidosis when their glucose levels are out of control. Type 2s seldom do. When their sugar is out of control too long, the develop a condition called hyperosmolarity.

They are distinctly different. The damage is the same. My mom was type 1, my dad was type2, my brother is type2 and my husband is type 2. I'm pretty famaliar with both types unfortunately.

missy'smom Collaborator

Ken,

Have you had the fasting serum C-peptide test done? That is a basic measure of how much insulin you are putting out and can help determine if you are T1 or T2. My doc thought I was T2 and very insulin resistant. But, I thought differently and asked for the test. It was very revealing.

I've been reading about LADA which bears some striking similarities to celiac disease. It seems that something may trigger the autoimmune reaction. There is a test that can be done for this type too-to check for certain antibodies-GAD. It would be great if this immune reaction could be diagnosed early and a vaccine or something given to stop the killer cells from destroying the pancreatic beta cells.

Although neesee is right, it is wise to use diagnostic resources to determine types and not go too much by profiles, people can vary and there are more kinds of diabetes than just T1 and T2.

neesee Apprentice
Open Original Shared Link
missy'smom Collaborator

Here is a more detailed explanation of LADA for anyone who might be interested. ADA may not be officially using that term with their patients according to the above link but they are here Open Original Shared Link

and endos are doing the testing and giving DX using this term.

I hope you didn't take my comment as a personal slight neesee. My frustration is with the docs. Too many Docs go by the profiles and don't look further which is why I said what I said. I was litteraly laughed at by one and dismissed by many others when I mentioned my concerns, because I didn't fit the profile. If I take the risk assesment quiz at the ADA website, it shows that I have very little risk! :blink:

It is beyond me why Ken and I and many others can't get a straight DX from the beginning. The Docs. have all the resources they need to make an accurate Dx. Simple, clear, accurate tests. It's not rocket science! Managing BGs is another matter. I don't know why they play around with management before they collect all the data they need to make their decisions!

Sorry, I couldn't get a direct link to the article that I wanted to post. If you click on the one above and click on Diagnosing Diabetes at the top and then click on LADA, at the bottom there is a reference link to Diabetes Care-it will have the ADA logo on the top of the page.

kenlove Rising Star

Thanks neesee &'missy'smom'

I think part of my problem is the HMO-- I'm also focused on the Dr bernstein approach (Thanks again 'missy'smom' !) as well as what all the healers were telling me in south india. Bitter melon juice tastes terrible but it's amazing how well it works to bring the blood sugar down.

I'm also focusing on my wifes new health problems since mine is managable for now.

I dont remember which tests I had as it was before I left the country. I did ask for some updated tests to which he wrote back that waiting a little longer would be better. My guess is that they want to see how much weight I loose and what type of affect it has if any. I have lost 20- some pounds in 2 months.

Wish I knew if my grandparents were type one or 2 but I dont know if they knew the differences in the early 50s.

ken

Here is a more detailed explanation of LADA for anyone who might be interested. ADA may not be officially using that term with their patients according to the above link but they are here Open Original Shared Link

and endos are doing the testing and giving DX using this term.

I hope you didn't take my comment as a personal slight neesee. My frustration is with the docs. Too many Docs go by the profiles and don't look further which is why I said what I said. I was litteraly laughed at by one and dismissed by many others when I mentioned my concerns, because I didn't fit the profile. If I take the risk assesment quiz at the ADA website, it shows that I have very little risk! :blink:

It is beyond me why Ken and I and many others can't get a straight DX from the beginning. The Docs. have all the resources they need to make an accurate Dx. Simple, clear, accurate tests. It's not rocket science! Managing BGs is another matter. I don't know why they play around with management before they collect all the data they need to make their decisions!

Sorry, I couldn't get a direct link to the article that I wanted to post. If you click on the one above and click on Diagnosing Diabetes at the top and then click on LADA, at the bottom there is a reference link to Diabetes Care-it will have the ADA logo on the top of the page.


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