Jump to content

  • You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Tests Results I'm Confused

Tigerpawtoo

Recommended Posts

Tigerpawtoo Newbie
Tigerpawtoo
Posted

I've been suffering various symptoms over the last three years. Tested slight RA positive, have Reynaud's - but tests for Sjogrens and Lupus negative. I'm frustrated the Dr's can't find the cause. My recent search led me to Celiac. I've been ordering my own blood work hoping for answers, but now that I have my results back I'm confused.

 

All negative but a slight low immunoglobin A Qn. Spent hours researching this, so far it seems I may need additional tests to rule out Celiac's disease? One site said AGA and EMA are required when you have a low immuniglobulin - I think these were done with my blood panel but I'm not sure.

 

Also another site said that if you do have a low immunoglobulin A Qn other antibodies testing for autoimmune disease may show a false negative. Does this mean I could still have Lupus or Sjogrens but test negative????

 

Should I be concerned and what other test would I need if any?????  It's been so long and I'm so frustrated having no answer, appreciate any help or direction.

 

Test results:

Deamidated Gliadin Abs, IgA          3       (negative 0-19)

Deamidated Gliadin Abs, IgG          2       (negative 0-19)

 

t-Transglutaminase (tTG) IgA         <2      (negative 0-3)

t-Transglutaminase (tTG) IgG         <2      (negative 0-5)

 

Endonysial Antibody IgA               negative

 

Immunoglobulin A, Qn, Serum     flagged as low - 90    (negative 91-414)

 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mushroom Proficient
mushroom
Posted

When your Immunoglobulin A, Qn, Serum is out of range, they usually run the IgG versions of the tests instead of the IgA.  In your case you have had both the DGP and the tTG IgG run already.  You would need the AGA IgG and the EMA IgG run.

 

I do not know how low total IgA would affect testing for other autoimmune diseases.  Interesting that you have a weak positive for RA.  Mine was completely negative.

 

Welcome to the board, and keep asking questions and pushing :)   It's the only way we get anywhere.

nvsmom Community Regular
nvsmom
Posted

...Everything Mushroom said.  :)

 

Beaware that you could have no-celiac gluten intolerance (NCGI) for which there are no blood tests at this time even though it is many many times more common. Celiac is starting to be considered just one end of the gluten intolerance spectrum; NCGI is just another way that gluten can have a bad effect on people's health.

 

Good luck.

Tigerpawtoo Newbie
Tigerpawtoo
Posted
  • Author

When your Immunoglobulin A, Qn, Serum is out of range, they usually run the IgG versions of the tests instead of the IgA.  In your case you have had both the DGP and the tTG IgG run already.  You would need the AGA IgG and the EMA IgG run.

 

I do not know how low total IgA would affect testing for other autoimmune diseases.  Interesting that you have a weak positive for RA.  Mine was completely negative.

 

Welcome to the board, and keep asking questions and pushing :)   It's the only way we get anywhere.

Thank you so much, hopefully i can find these tests online - do they have other names they may go by? I have a hard time matching up the right tests.

I also tested high for thyroid peridoxidase (sp) but all other thyroid tests normal. I tested ANA positive two weeks ago, but then ran the ANA IFA test for the titer and it was negative. I'm seeing a new rheumatologist, but so far she's not doing any testing, just relying on all the negative tests that were run last year. I have no idea what direction she's taking next. I have a lot of shoulder pain and numbness/weakness so she did an MRI to rule out any neck issues. But I haven't heard back and there is no way this could be causing all my other bizarre symptoms.

 

I'm also seeing a lyme specilaist next month but it has taken 5 months for this appointment. I  lost my job as I have so many horrible days - after three years I'm so desperate for answers to get my life back. Curious can celiac disease or intolerance cause you to be stuck on the couch for a day or two feeling so weak you can't get up?

Thank you so very much for you reply.

Tigerpawtoo Newbie
Tigerpawtoo
Posted
  • Author

...Everything Mushroom said.  :)

 

Beaware that you could have no-celiac gluten intolerance (NCGI) for which there are no blood tests at this time even though it is many many times more common. Celiac is starting to be considered just one end of the gluten intolerance spectrum; NCGI is just another way that gluten can have a bad effect on people's health.

 

Good luck.

thank you so much, I'm seeing a lyme specialist in a month I think after that I may do  trial gluten free diet, I have nothing else left to try - I think i've tested my blood for everything I can come up with, lol.

mushroom Proficient
mushroom
Posted

Thank you so much, hopefully i can find these tests online - do they have other names they may go by? I have a hard time matching up the right tests.

The AGA stands for Anti-Gliadin Antibodies and the EMA stands for Endomysial Antibodies.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      134,083
    • Most Online (within 30 mins)
      10,442
    Melvac
    Newest Member
    Melvac
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      Sigh. I posted this yesterday based on the Safeway website. I went back again today to their website to double check. On the page where they are selling Vanilla Bean flavor, it has a distinct Certified Gluten Free label. Other flavors on the Safeway website didn't have the gluten-free statement. Today I went into the store. None of the flavors I looked at, including Vanilla Bean, have a Gluten Free statement. Is it safe? Who knows. The ingredients are either safe or nearly safe (some have "natural flavor"). There are warnings about "contains milk and soy" but not about wheat - this implies they are safe, but again, who knows. On the other hand, every flavor I checked of their Slow Churn line of ice creams has wheat as an ingredient. 100% not safe.
    • knitty kitty
      Edy's and Dreyer's ice cream

      By knitty kitty · Posted

      Do keep in mind that many of the newly diagnosed have lactose intolerance.  This is because the villi lining the intestinal tract are damaged, and can no longer make the enzyme lactAse which breaks down the milk sugar lactOse.  When the villi grow back (six months to two years), they can again produce the enzyme lactAse, and lactose intolerance is resolved.  However, some people (both those with and without Celiac Disease) are genetically programmed to stop producing lactase as they age.   Do be aware that many processed foods, including ice cream, use Microbial Transglutaminase, a food additive commonly called "meat glue," used to enhance texture and flavor.  This microbial transglutaminase has the same immunogenicity as tissue transglutaminase which the body produces in response to gluten in people with Celiac Disease.  Tissue Transglutaminase (tTg IgA) is measured to diagnose Celiac Disease in blood tests.  Microbial Transglutaminase acts the same as Tissue Transglutaminase, causing increased intestinal permeability and inflammation.   New findings show that microbial transglutaminase may be able to trigger Celiac Disease and other autoimmune and neurodegenerative diseases.   Microbial Transglutaminase is not required to be listed on ingredients labels as it's considered a processing aid, not an ingredient in the U.S.  Microbial Transglutaminase has been GRAS for many years, but that GRAS standing is being questioned more and more as the immunogenicity of microbial transglutaminase is being discovered. Interesting Reading:  Microbial Transglutaminase Is a Very Frequently Used Food Additive and Is a Potential Inducer of Autoimmune/Neurodegenerative Diseases https://pmc.ncbi.nlm.nih.gov/articles/PMC8537092/
    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      There is a 10 year old post in this forum on Edy's and Dreyer's ice cream. The information is somewhat outdated and the thread is closed to further comment, so here is a new one. Edy's And Dreyer's Grand Vanilla Bean Ice Cream - 1.5 Quart is labeled "Gluten Free". This is a different answer than years gone by. I don't know the answer for any other flavor at this moment. On 1 May, 2026, Edy's website says: "As a general rule, the gluten in Edy's and Dreyer's® frozen dessert products is present only in the added bakery products, such as cookies, cake or brownies. We always label the eight major food allergens on our package by their common name. We recommend to always check the label for the most current information before purchasing and/or consuming a product. The exception to this rule is our Slow Churned French Silk frozen dairy dessert, which contains gluten in the natural flavors." https://www.icecream.com/us/en/brands/edys-and-dreyers/faq It seems that Edy's and Dreyer's are more celiac-friendly than they were 10 years ago. Once I found enough information to make today's buying decision, I stopped researching.
    • Aretaeus Cappadocia
      EDG 3 years ago fine, now it shows focal villous blunting,

      By Aretaeus Cappadocia · Posted

      probably not your situation @Mimiof2, but allow me to add one more to @trents list of celiac-mimics: "olmesartan-induced sprue-like enteropathy"  
    • knitty kitty
      Terrible Neurological Symptoms

      By knitty kitty · Posted

      My dad had an Abdominal Aortic Aneurysm.  Fortunately, it was discovered during an exam.  The doctor could feel my dad's heart beating in his stomach/abdomen.  The aneurysm burst when the doctor first touched it in surgery.  Since he was already hooked up to the bypass machine, my dad survived ten more years.  Close call! Triple A's can press on the nerves in the spinal cord causing leg pain.  I'm wondering if bowing the head might have increased the pressure on an aneurysm and then the nerves.   https://gulfcoastsurgeons.com/understanding-abdominal-aortic-aneurysm-symptoms-and-causes/ Abdominal Aortic Aneurysm Presenting as a Claudication https://pmc.ncbi.nlm.nih.gov/articles/PMC4040638/
×
×
  • Create New...