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High Iga After Going gluten-free?

lisachrystine

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lisachrystine Newbie
lisachrystine
Posted

My 7 year old was diagnosed with Celiac via blood test and biopsy over a year ago. At the time, when he was eating gluten, his IgA was normal, but the other two (TTG and something else that I can't remember now) were super high. Since going gluten-free, those two have returned to normal, but the last two blood tests show his IgA as being high now when it wasn't before. Is there another reason why this particular marker would change when it appears that his Celiac is under control with the other two negative results and no symptoms. He is pretty sensitive to gluten - usually gets sick within 24 hours of ingesting it -- and it doesn't have to be a lot to make him sick. So, I'm pretty sure there's nothing sneaky going on. What else might cause this? Any ideas?

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frieze Community Regular
frieze
Posted

Is it his total IgA that is up?

nvsmom Community Regular
nvsmom
Posted

The total serum IgA is not actually a celiac test. It is a control test to ensure that the patient makes enough IgA to have an accurate ceilac test.

 

I don't know of any problems related to a high IgA. I have heard that a low IgA is often linked to autoimmune disorders - like celiac. Perhaps (and this is only a non-medically trained guess) now that his inflammation is coming down, and his disease is under control, his IgA levels went up?  Just a guess though.

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Hope you find answers... And congrats on treating your son's celiac -with those labs it looks like you've done a great job.  :)

lisachrystine Newbie
lisachrystine
Posted
  • Author

I honestly don't remember the exact test. It was a quick look at it at the GI's office yesterday. I was going to call and have them send me the labs so I can be more specific. I guess I was concerned about other issues - not so much Celiac-related, but maybe other allergies or something? It was just strange to me that it changed. My 4 yo daughter (the first diagnosed with Celiac) has completely normal labs. Everything was high on diagnosis and everything is normal now - the response we'd expect, so when his came back different, it threw me.

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    • trents
      Celiac flare years after diagnosis

      By trents · Posted

      Unless gluten exposure is happening on a regular basis, it is doubtful that blood antibodies would show up elevated in testing. It takes time for them to build up to detectable levels.
    • Russ H
      Celiac flare years after diagnosis

      By Russ H · Posted

      HI Nancy, In your first post, you said that you were diagnosed by biopsy and blood test - this is what I was referring to: the blood test is for antibodies that are made during active disease. After a period on a strictly gluten-free diet, the antibodies return to low level. It is a good way of checking for accidental exposure if symptoms persist. If you are reacting to foods that don't contain gluten, you may be reacting to something else. Alternatively, a condition called SIBO is common in people with coeliac disease, where there is an overgrowth of bacteria in the small intestine. This can be tested for with a simple breath test. The main treatment is with a course of antibiotic. Small Intestinal Bacterial Overgrowth (SIBO)
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    • nancydrewandtheceliacclue
      Celiac flare years after diagnosis

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      Hi Trent, no dairy. Other than good quality butter. I have been lactose free for years. No corn, sugar, even seasonings and spices. I don't eat out. I cook my own food.
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      Celiac flare years after diagnosis

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      @nancydrewandtheceliacclue, are you consuming dairy? Not sure if dairy is part of the carnivore diet.
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