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Blood Tests Are In


SimonSez0721

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SimonSez0721 Rookie

Ok, so, I have an advance copy of my blood work from last weeks celiac panel but do not have an appointment to go back to have a consultation until December 2. I'm hoping some of you will be able to help me interpret these numbers.

In addition to gas, bloating, and cramps, I am also currently suffering with the following:

Fibromyalgia, CFS, migraines, myofacial pain syndrome, degenerative disc disease, patellofemoral syndrome, benign hyper-mobility, insomnia, anxiety and depression secondary to living with chronic pain for 25 years, kidneystones, and a recent gallbladder removal secondary to pancreatitis.

It appears to me, however, that Celiac might not be the cause of all that ails me?

tTG. 19. 19 or less = normal

Endomysial <1:10

Reticulin Antibody negative

A few non-celiac but interesting numbers:

ESR Sed rate 8

Lipase 16

Basophil% Reference range 0.0-5.0%. Mine is 0.6. They've never checked this before for me. Hm, that's of some interest...

Does anybody have any thoughts?

thank you in advance, your input to my previous post was so amazing. I am so grateful for everyone's insight!

Thank you,


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nvsmom Community Regular

I'm guessing that your doctor will probably declare you normal because your results are technically in range, but I don't know if I agree. With your symptoms, and a borderline tTG IgA, I think celiac disease could be a possibility for you. An EMA titre of 1:10 is sometimes sonsidered positive as well (depends on the lab). If that is the case with you, then I think celiac disease is pretty much a sure thing. An EMA test is only positive when the damage to the villi is pretty extensive and the disease is well established - it's very specific to celiac disease.

 

Good luck with your appointment. Are staying on gluten until then?

SimonSez0721 Rookie

Thank you for your reply,

Yes, I am staying on gluten until after my doctor reviews my labs and decides whether or not to request an endoscopy. He did say that he felt the lab work was not super reliable, so maybe he will feel like following up with additional studies it they are close enough to being weak positive.

I was remembering, that my daughter, was having daily stomach aches at the age of 8. Her doctors were never able to find a cause but casually mentioned once, "Oh, by the way, we tested you for food allergies. You are allergic to peanuts, egg whites, and wheat."

Hm. Curious.

nvsmom Community Regular

Allergies are a different part of the immune system than what is affected by celiac disease,although celiacs do seem to have many allergies. Allergies are through the immunoglobulin E (IgE) system whereas celiac disease is in the IgA (mucosal linings) and IgG (system wide dealing with pathogens). There could be a link, but I personally don't know of it.

JustCricket Newbie

Basophils are one of the white blood cells. I believe they are associated with allergy and correlate with IgE. (Stretching my study of Immunology from a few years ago.) 

 

My neutrophil and C reactive protein (both associated with inflammation) were tested a few years back, so this is just another check on your immune system, to see if there is a possible infection or allergy going on. 

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    • trents
      Unless gluten exposure is happening on a regular basis, it is doubtful that blood antibodies would show up elevated in testing. It takes time for them to build up to detectable levels.
    • Russ H
      HI Nancy, In your first post, you said that you were diagnosed by biopsy and blood test - this is what I was referring to: the blood test is for antibodies that are made during active disease. After a period on a strictly gluten-free diet, the antibodies return to low level. It is a good way of checking for accidental exposure if symptoms persist. If you are reacting to foods that don't contain gluten, you may be reacting to something else. Alternatively, a condition called SIBO is common in people with coeliac disease, where there is an overgrowth of bacteria in the small intestine. This can be tested for with a simple breath test. The main treatment is with a course of antibiotic. Small Intestinal Bacterial Overgrowth (SIBO)
    • Aretaeus Cappadocia
      I'm not saying this is what you have, but your description reminds me of Morgellons, which are not very well understood. Here is a review from a reputable source. If it seems similar to your experience, you could raise this question with your Dr.  https://my.clevelandclinic.org/health/diseases/morgellons-disease
    • nancydrewandtheceliacclue
      Hi Trent, no dairy. Other than good quality butter. I have been lactose free for years. No corn, sugar, even seasonings and spices. I don't eat out. I cook my own food.
    • trents
      @nancydrewandtheceliacclue, are you consuming dairy? Not sure if dairy is part of the carnivore diet.
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