Jump to content

  • You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Autoimmunity and TTG

Jenny0409

Recommended Posts

Jenny0409 Rookie
Jenny0409
Posted

So recently I had a really high positive on the TTG IGA leading my doctor to believe I have Celiac. For a host of reasons, for the time being, I'm not going through with the endoscopy. I have been completely gluten free from day I got my results. I have no intention of going back on gluten. I had a previous diagnosis of Graves Disease(Hyperthyroidism) last year and in December had my thyroid completely removed. The doctor tested for Celiac because of my ongoing symptoms such as intense muscle spasm/cramps, bone pain, low calcium, low Vitamin D, the list goes on. Anyway, in conjunction with the Celiac panel he decided to have me to an ACTH. I learned that test is for Addisions and other Adrenal issues. My questions is, could the presence of Addisions cause a false positive on the TTG IGA? I feel sure I have Celiac but I'm not sure about Addision. Are they often found together? If so, that would put me at a grand total of 3 autoimmune disorders. Is that common?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Scott Adams Grand Master
Scott Adams
Posted

I've not heard of Addison's causing a false positive on any celiac disease screening results. 

 

nvsmom Community Regular
nvsmom
Posted

I doubt it too. 95% of the time a positive ttG IgA is caused by celiac disease. The other 5% of the time, a weak positive is caused by hashimoto's, liver disease, diabetes, crohn's, colitis, or a serious infection.  I would say you probably have celiac disease.  :(

Jenny0409 Rookie
Jenny0409
Posted
  • Author

I think so too. However, my only concern was if the antibodies from having had Graves could still be floating around causing a false positive. But my positive TTG test was not a weak positive it was a very strong positive so it's likely that it is Celiac I suppose. 

nvsmom Community Regular
nvsmom
Posted

Yeah... :(  Usually false positive are pretty weak.

I have celiac disease, Hashi's, and ITP (and I still suspect MCTD or something similar).  My ttG IgA took over a year to get back into normal, and then it was still a high normal for another year. My Hashi's might have kept it up a bit, and even now it is about a 5 out of 14 - still not super low.

You'll find many of us have multiple issues that slows recovery somewhat.  You're in good company.  ;)

Jenny0409 Rookie
Jenny0409
Posted
  • Author

The scale for my TTG IgA test was 0-3 negative, 4-10 weak positive, and above 10 positive. I was a 16. Guess that is pretty positive lol The denial is something I didn't expect. I know it's stupid to feel like maybe I don't have it when all signs point to a big fat yes. I know intellectually that I have to stay Gluten free and I'm doing very well on the gluten-free diet if I do say so myself. I slipped once (damn you pumpkin spice lattee) and I paid for it with two days of muscle cramps, bone pain, brain fog, and depression. That was enough to keep me away from that poison forever let me tell you. I though I was home free at first because the symptoms didn't hit until the next day. They were so evident that even my husband noticed the dramatic shift in my physical state and attitude.

nvsmom Community Regular
nvsmom
Posted

Yep, that's pretty positive. Five times above normal.  ;)

Ah yes, evil pumpkin spice latte....Well, on the bright side, it is often easier to stay away from risky cc situations when the symptoms are obvious.  I think it can be tough to stay gluten-free when you don't feel this disease.  KWIM?

Hang in there.  You'll have the hang of this diet before Xmas rolls around.  Hopefully you'll be really noticing improvements by then too.  :)

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      134,077
    • Most Online (within 30 mins)
      10,442
    terrificterry
    Newest Member
    terrificterry
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Who's Online (See full list)

    • There are no registered users currently online

  • Upcoming Events

  • Posts

    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      Sigh. I posted this yesterday based on the Safeway website. I went back again today to their website to double check. On the page where they are selling Vanilla Bean flavor, it has a distinct Certified Gluten Free label. Other flavors on the Safeway website didn't have the gluten-free statement. Today I went into the store. None of the flavors I looked at, including Vanilla Bean, have a Gluten Free statement. Is it safe? Who knows. The ingredients are either safe or nearly safe (some have "natural flavor"). There are warnings about "contains milk and soy" but not about wheat - this implies they are safe, but again, who knows. On the other hand, every flavor I checked of their Slow Churn line of ice creams has wheat as an ingredient. 100% not safe.
    • knitty kitty
      Edy's and Dreyer's ice cream

      By knitty kitty · Posted

      Do keep in mind that many of the newly diagnosed have lactose intolerance.  This is because the villi lining the intestinal tract are damaged, and can no longer make the enzyme lactAse which breaks down the milk sugar lactOse.  When the villi grow back (six months to two years), they can again produce the enzyme lactAse, and lactose intolerance is resolved.  However, some people (both those with and without Celiac Disease) are genetically programmed to stop producing lactase as they age.   Do be aware that many processed foods, including ice cream, use Microbial Transglutaminase, a food additive commonly called "meat glue," used to enhance texture and flavor.  This microbial transglutaminase has the same immunogenicity as tissue transglutaminase which the body produces in response to gluten in people with Celiac Disease.  Tissue Transglutaminase (tTg IgA) is measured to diagnose Celiac Disease in blood tests.  Microbial Transglutaminase acts the same as Tissue Transglutaminase, causing increased intestinal permeability and inflammation.   New findings show that microbial transglutaminase may be able to trigger Celiac Disease and other autoimmune and neurodegenerative diseases.   Microbial Transglutaminase is not required to be listed on ingredients labels as it's considered a processing aid, not an ingredient in the U.S.  Microbial Transglutaminase has been GRAS for many years, but that GRAS standing is being questioned more and more as the immunogenicity of microbial transglutaminase is being discovered. Interesting Reading:  Microbial Transglutaminase Is a Very Frequently Used Food Additive and Is a Potential Inducer of Autoimmune/Neurodegenerative Diseases https://pmc.ncbi.nlm.nih.gov/articles/PMC8537092/
    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      There is a 10 year old post in this forum on Edy's and Dreyer's ice cream. The information is somewhat outdated and the thread is closed to further comment, so here is a new one. Edy's And Dreyer's Grand Vanilla Bean Ice Cream - 1.5 Quart is labeled "Gluten Free". This is a different answer than years gone by. I don't know the answer for any other flavor at this moment. On 1 May, 2026, Edy's website says: "As a general rule, the gluten in Edy's and Dreyer's® frozen dessert products is present only in the added bakery products, such as cookies, cake or brownies. We always label the eight major food allergens on our package by their common name. We recommend to always check the label for the most current information before purchasing and/or consuming a product. The exception to this rule is our Slow Churned French Silk frozen dairy dessert, which contains gluten in the natural flavors." https://www.icecream.com/us/en/brands/edys-and-dreyers/faq It seems that Edy's and Dreyer's are more celiac-friendly than they were 10 years ago. Once I found enough information to make today's buying decision, I stopped researching.
    • Aretaeus Cappadocia
      EDG 3 years ago fine, now it shows focal villous blunting,

      By Aretaeus Cappadocia · Posted

      probably not your situation @Mimiof2, but allow me to add one more to @trents list of celiac-mimics: "olmesartan-induced sprue-like enteropathy"  
    • knitty kitty
      Terrible Neurological Symptoms

      By knitty kitty · Posted

      My dad had an Abdominal Aortic Aneurysm.  Fortunately, it was discovered during an exam.  The doctor could feel my dad's heart beating in his stomach/abdomen.  The aneurysm burst when the doctor first touched it in surgery.  Since he was already hooked up to the bypass machine, my dad survived ten more years.  Close call! Triple A's can press on the nerves in the spinal cord causing leg pain.  I'm wondering if bowing the head might have increased the pressure on an aneurysm and then the nerves.   https://gulfcoastsurgeons.com/understanding-abdominal-aortic-aneurysm-symptoms-and-causes/ Abdominal Aortic Aneurysm Presenting as a Claudication https://pmc.ncbi.nlm.nih.gov/articles/PMC4040638/
×
×
  • Create New...