Celiac.com Sponsor (A1):



Celiac.com Sponsor (A1-m):


0
zs1994

Negative blood test but still concerned!

Rate this topic

Recommended Posts

Hi all,

Back in September, I had stomach issues for a few weeks. My doctor said it was a virus but ordered me a blood test for Coeliac Disease as my sister has the condition. My results came back as:

Tissue Transglutaminase Antibodies (tTG-IgA) : 4.9 (5.00 - 20.00) 

Doctor said nothing to worry about. However I still have periods where I have gas and soft stools (not diahoerra). Also, my sleeping pattern has been a mess since September and I've had mouth ulcers at least twice since then too. Is it worth going back and asking for a biopsy? 

Thank you all in advance!

Share this post


Link to post
Share on other sites

Join eNewsletter


Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8):


Before asking for a biopsy, you might ask for a complete celiac blood panel:

-Tissue Transglutaminase (tTG) IgA and (tTG) IgG
-Deamidated Gliadin Peptide (DGP) IgA and (DGP) IgG
-EMA IgA 
-total serum IgA and IgG (control test)
-AGA IGA and AGA IgG - older and less reliable tests largely replace by the DGP tests
 
-endoscopic biopsy - make sure at least 6 samples are taken
 
VERY IMPORTANT:  Keep eating gluten daily until ALL testing is complete or the tests can be inaccurate.  
 
(Source: NVSMOM -- ?)
 
Why the full panel?  The TTG does not catch everyone.   My TTG tests are always negative (even in follow-up testing).  I was positive on only the DGP IGA.  Go figure!  How did your sister test?  

 

Welcome to the forum and let us know how it goes! 

 

Non-functioning Gall bladder Removal Surgery 2005

Diagnosed via Blood Test and Endoscopy: March 2013

Hashimoto's Thyroiditis -- Stable 2014

Anemia -- Resolved

Fractures (vertebrae): June 2013

Osteopenia/osteoporosis -- June 2013

Allergies and Food Intolerances

Diabetes -- January 2014

Celiac.com - Celiac Disease Board Moderator

Share this post


Link to post
Share on other sites

Join eNewsletter

I tested Negative in August on the celiac panel. My symptoms continued and I had to go back to my doctor for a follow up on my anemia.  She referred me to a GI doctor because my numbers didn't improve.  The GI doctor felt that I didn't have celiac, but she ran the genetic test to be thorough and so that we could confidently eliminate it from the list of potential diagnoses.  The genetic test  came back positive.  Since I'm having symptoms I'm getting an EGD with biopsies in a couple of weeks.  The doctor said that she rarely sees people test negative on the panel and have celiac, but it does happen, and there's no explanation to why it happens because our bodies are complex.

My take on your situation; if you aren't confident that celiac isn't your problem and you haven't exhausted all testing options, then keep going.  You only get one body and one life and nobody is going to advocate for you as well as you.

Share this post


Link to post
Share on other sites

Join eNewsletter

2 hours ago, CherylS said:

I tested Negative in August on the celiac panel. My symptoms continued and I had to go back to my doctor for a follow up on my anemia.  She referred me to a GI doctor because my numbers didn't improve.  The GI doctor felt that I didn't have celiac, but she ran the genetic test to be thorough and so that we could confidently eliminate it from the list of potential diagnoses.  The genetic test  came back positive.  Since I'm having symptoms I'm getting an EGD with biopsies in a couple of weeks.  The doctor said that she rarely sees people test negative on the panel and have celiac, but it does happen, and there's no explanation to why it happens because our bodies are complex.

My take on your situation; if you aren't confident that celiac isn't your problem and you haven't exhausted all testing options, then keep going.  You only get one body and one life and nobody is going to advocate for you as well as you.

Hi, thank you for your reply. I plan on going back for peace of mind. Can you describe your continuing symptoms after your blood test please? 

Share this post


Link to post
Share on other sites

Join eNewsletter

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Restore formatting

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

0


Join eNewsletter