Jump to content

  • You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Genetic Testing for celiac

CeliacMommaX2

Recommended Posts

CeliacMommaX2 Enthusiast
CeliacMommaX2
Posted

My husband and I have been convinced to go through genetic testing (if not too expensive).  I have a few questions...

Do I ask the doctor's office or call our insurance about how much it will cost?

If both my husband and I have both genes, does that mean all of our children will also have both genes?  We already have 2 with celiac, so it seems our odds are high...  I wonder if we would need to bother getting the non-celiac kids tested if that was the case.

Is there any reason to test a person who has already been diagnosed with celiac?  (probably a stupid questions, but I'm asking anyway :) )

Thanks!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


pschwab Enthusiast
pschwab
Posted

I'm not an expert by any means but I'll tell you our experience. My three year old was diagnosed based upon a very high ttg level and a positive genetic test. My husband got tested and has the gene but hasn't triggered celiac. My 7 year old has the gene but not celiac. My 5 year old doesn't have the gene. I haven't been tested because I figure it's coming from my husband's side, but I might still be tested just in case when the baby is old enough to be tested. I questioned our gi dr about the combination of genetic markers for the three of them with the gene. He said he would look over the genetic tests to see what their individual combinations could tell us. He did confirm my question about different genetic combinations raising or lowering the chance of triggering celiac. The advice we got was to monitor all immediate family members (blood tests every two years or sooner if showing signs of celiac). We chose genetic testing so we could potentially rule out having to test some kids continually. We just requested it from our regular dr and didn't contact insurance ahead of time. If someone is already diagnosed with celiac you wouldn't have to do genetic testing on them. Hope this helps a bit

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Aretaeus Cappadocia
      - Aretaeus Cappadocia replied to JForman's topic in Coping with Celiac Disease
      8

      7yo struggling!

      Actually, human agriculture only started 10-12,000 years ago, while the Neanderthals were gone by 30,000 years ago (and greatly diminished long before then).
    2. Aretaeus Cappadocia
      - Aretaeus Cappadocia replied to JForman's topic in Coping with Celiac Disease
      8

      7yo struggling!

      In addition to the other advice offered, perhaps you could identify some good recipes for gluten-free treats that you could make at home with your child, and maybe make a little fuss over how good gluten-free treats are. I regularly make gluten-free banana bread with different recipes that use buckwheat, garbanzo bean, etc flours, gluten-free ginger snaps...
    3. Aretaeus Cappadocia
      - Aretaeus Cappadocia commented on Jefferson Adams's article in Origins of Celiac Disease
      8

      Celiac Disease Linked to Neanderthal Ancestry

      From the original post: "Some indicate negative effects, with putative links to various diseases as measured by genome-wide association studies (Sankararaman et al. 2014. Simonti et al. 2016)." ---> The links in the original post lead to a different article. I think these might be the correct links: "The landscape of Neandertal ancestry in present...
    4. Aretaeus Cappadocia
      - Aretaeus Cappadocia commented on Jefferson Adams's article in Diagnosis, Testing & Treatment
      4

      Scientists Make Major Advance in Autoimmune Disease Therapy

      The main use for leukapheresis is to mitigate (not cure) certain blood disorders, particulary certain types of blood cancer. It's kind of like "thinning the herd" when your body makes too many white blood cells. Doesn't fix the underlying problem, but it buys some time. The car-T people utilize the same technology to collect enough T cells (a type of...
    5. Scott Adams
      - Scott Adams commented on Scott Adams's article in Additional Concerns
      8

      This Common Blood Pressure Drug Can Mimic Celiac Disease Symptoms

      Olmesartan is the ARB most strongly linked to sprue-like enteropathy, a condition that can closely mimic celiac disease with diarrhea, weight loss, villous atrophy, and often negative celiac blood tests. Some newer reports suggest this reaction may not be limited to olmesartan and could represent a possible ARB class effect, with cases reported for drugs...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      134,111
    • Most Online (within 30 mins)
      10,442
    greatsocalgal
    Newest Member
    greatsocalgal
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Aretaeus Cappadocia
      7yo struggling!

      By Aretaeus Cappadocia · Posted

      Actually, human agriculture only started 10-12,000 years ago, while the Neanderthals were gone by 30,000 years ago (and greatly diminished long before then).
    • Aretaeus Cappadocia
      7yo struggling!

      By Aretaeus Cappadocia · Posted

      In addition to the other advice offered, perhaps you could identify some good recipes for gluten-free treats that you could make at home with your child, and maybe make a little fuss over how good gluten-free treats are. I regularly make gluten-free banana bread with different recipes that use buckwheat, garbanzo bean, etc flours, gluten-free ginger snaps, etc. This might have the most impact if it's a novel treat unknown to the kids in a glutenated form. Best wishes.
    • Wheatwacked
      Symptoms Dismissed

      By Wheatwacked · Posted

      Chronic fatigue in the producer was the inspiration for the episode but I feel it touches on anyone that suffers and is dismissed as psycosomatic. The patient expressed my feelings elequently.  In episode 2 the doctor explains the problem well. I stopped all commercial milk protein like skim milk added to processed foods and in a few days there was a definate improvement in my  gut, bowel movements, discomfort etc. Still drinking several glasses of Pasture Fed grass fed milk with no negative effects.   Specifically, for myself Clonidine is the only medication that lowers my BP and the doctor did not renew it, insisting that I continue Losartan.  I think that she thinks I am abusing Clonidine and the reason the Losartan doesn't work is because I am non-compliant.  Absolutely not. Surprisingly after a few days withdrawal from the Clonidine my fasting blood sugar has gotten under control.  Fasting blood sugar near normal instead of over 160.  Last few days its been below 100.  I still need Glimiperide.  Without the clonidine my pulse rate is around 100 bpm, with it around 60.   Prescription of angiotensin receptor blockers in celiac disease is associated with persistent symptoms and surrogate markers of malabsorption.  https://pmc.ncbi.nlm.nih.gov/articles/PMC12323722/ Angiotensin receptor blocker-associated enteropathy (ARB-e) is an increasingly recognised clinical entity with symptoms and histological findings identical to coeliac disease (celiac disease). There is evidence to suggest immune-mediated mucosal injury in ARB-e with a high prevalence of DQ2/DQ8; however, as IgA anti-tissue transglutaminase (anti-TTG) is usually negative   https://onlinelibrary.wiley.com/doi/full/10.1002/ueg2.12117 NEW research [Nov 2024] presented at the American College of Gastroenterology (ACG) Annual Scientific Meeting suggests that angiotensin receptor blockers (ARBs), a class of drugs commonly used to manage hypertension, may be associated with poorer outcomes in patients with coeliac disease. Findings indicated that patients taking ARBs had a higher likelihood of experiencing persistent symptoms and markers of poor small bowel healing, such as anaemia and iron deficiency.  https://www.emjreviews.com/en-us/amj/gastroenterology/news/angiotensin-receptor-blockers-may-worsen-coeliac-disease-outcomes/
    • mermaidluver22
      Some inflammation in ileum with celiac?

      By mermaidluver22 · Posted

      @BarcinoHi! I am so sorry abt your son but also relieved to know I am not alone! My ttg iga is still mildly elevated but going down. Last time we checked I had some small erosions in my ileum but recently got an MRE that showed no inflammation. Calpro 70. We are still in limbo but we are taking a conservative approach as well. Please keep me updated about his situation and outcomes! I always love to hear others opinions/experiences especially ibd specialists. 
    • Scott Adams
      still struggling with cravings

      By Scott Adams · Posted

      Celiac.com has published a book on our site by Jean Duane PhD called Gluten-Centric Culture, which covers many of the social aspects of having celiac disease: This chapter in particular covers issues around eating with family and others - Gluten-Centric Culture: Chapter 5 - Grabbing A Bite Together:    
×
×
  • Create New...