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Gliadin (Deamidated Peptide) Antibody (IgG) - HELP

MamaofThree
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MamaofThree Newbie
MamaofThree
Posted

Hi all! Thanks for letting me join the forum.

My husband is waiting for some additional bloodwork to come back. We originally ordered all of these labs to rule out Celiac and other digestive health stuff thinking my husband had IBS. However, we just got the results back for the Gliadin Deamidated Peptide IGG Antibody. 

It says the antibody WAS detected and that it was 28.2 (anything over 15 is positive per this lab).

We're waiting for the rest of the panels to come back but I'm in a rabbit hole here. Is there any way for him to have this antibody and NOT have Celiac?

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trents Grand Master
trents
Posted

Welcome to the forum @MamaofThree!

It is possible for your husband to have elevated DGP-IGG and not have celiac disease. None of the antibody tests given to diagnose celiac disease are 100% specific, meaning there are some other possible causes for the elevation. DGP-IGG is considered a secondary celiac antibody test and not as specific as the tTG-IGA or the EMA. But it is specific enough to present a very good possibility that if it is elevated, it means someone does have celiac disease. Here is an overview of the various blood tests and their relative sensitivity/specificity used to diagnose celiac disease: 

 

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      By Newhere19 · Posted

      Thank you both. I haven't had access to the test results but will get them and post here.
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      Duodenal ulcers are not uncommon either and often result from H.Pylori infections. https://www.healthdirect.gov.au/duodenal-ulcer
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