Thank you Scott, I appreciate your reply to my questions. I am definitely nervous about my neurology appointment tomorrow. I have kind of lost faith in physicians, I've had symptoms for 15 years and switched PCPs several times and I've just wondered if I'll ever have answers. I was sent to rheumatology first and that physician tried to tell me I wasnt having the symptoms I told him about and joked that all of us have memory problems as we age and that its normal to have white lesions at my age. I know its not normal (im an xray tech and use to do CT). My memory is definitely not the norm for a 44 year old. I have just had to fight, push, advocate, and research things myself. I sometimes feel like...

Your situation is intriguing—while the biopsy ruled out celiac disease, the elevated gliadin IgA (along with gastritis from H. pylori) suggests your immune system is reacting to gluten, albeit differently than in classic celiac. High gliadin IgA can occur in non-celiac gluten sensitivity (NCGS), other autoimmune conditions, or even as part of gut inflammation from H. pylori. Since active gastritis can disrupt the intestinal barrier ("leaky gut"), gluten might trigger temporary immune reactions that could calm post-recovery. The fact that you tolerated gluten accidentally doesn’t necessarily rule out sensitivity; symptoms can be delayed or cumulative. To clarify, consider retesting gliadin IgA...

Your experience highlights a fascinating and often overlooked connection between gut health, mental health, and medication efficacy—something many in the celiac community encounter. When you removed gluten, your body likely began healing, which can dramatically alter nutrient absorption, inflammation levels, and even neurotransmitter production (like serotonin, which SSRIs target). This shift might explain why your SSRI seemed to "stop working"—your gut wasn’t processing the medication (or nutrients critical for mood regulation) the same way it did pre-diagnosis. Switching to an NDRI (which works on dopamine/norepinephrine instead of serotonin) may have...