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Mama2Boys

Bloodwork - Negative Or Borderline? What Should My Next Step Be?

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Hi there! I'm new and have had GI and other immune symptoms for 10 years. (Age 32.) I also have Hashimoto's and my sister has Crohn's, so I was told by my doctor (he and his family are all either Celiac or gluten-free) it would be a good idea to rule out celiac disease.

I got my blood test results and they seem pretty straightforward negative, but he is on vacation for 10 more days (the nerve! ;) ) so I figured there must be some armchair experts around these parts!

My Endomysial Antibody IgA says Negative

t-Transglutaminase (tTg) IgA says 2 reference is (0-3 U/mL)

Immunoglobulin A, Qn, Serum says 186 reference is (70-400 mg/dL)

I guess I was hoping gluten would be the cause of my problems so I didn't have to deal with Crohn's. :(

Is Celiac out of the realm of possibility now?

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False negatives on testing are not uncommon. You could still be celiac even with negative blood work. If you are going to have an endo with biopsies then keep eating gluten until that is done. After all testing is done do a strict trial of the diet to see if it helps.

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My doctor suggested upper and lower endos. He didn't mention biopsy but I imagine that is part of the package. <_<

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The GI specialist can't see me until December. I went nuts with the gluten on Monday and had the symptoms to prove it Monday night :( I don't think I can wait until December to try gluten-free, just for the sake of a biopsy that proves what I think I already know. I suppose the next step before going gluten-free could be Enterolab. From what personal research I have done, they seem legit and perhaps would help me know exactly what I am dealing with here.

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