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Celiac Disease & Gluten-Free Diet Blogs

Why Are Dietary Interventions Still Not Mainstream?

"Why Are Dietary Interventions Still Not Mainstream? While there is greater knowledge of the effects of pharmaceutical therapies for arthritis, there is less knowledge of the effects of many nutrients. And even though there is evidence that physician discussions of diet make a positive influence on patient dietary selections, these conversations are not common in clinical practice. There is a global deficiency of nutrition education in physician training, including the use of nutrients to m

knitty kitty

Glioblastoma and Niacin

I found this article about a study using high doses of Niacin to treat Glioblastoma.  Glioblastoma is an aggressive brain cancer. My mother died from Glioblastoma.   Can a Common Vitamin Fight the Most Aggressive Brain Cancer? https://scitechdaily.com/can-a-common-vitamin-fight-the-most-aggressive-brain-cancer/  And... A phase I-II study of niacin in patients with newly diagnosed glioblastoma: safety and interim phase II analysis https://link.springer.com/artic

knitty kitty

Is Thiamine Deficiency the Beginning of Celiac Disease?

I've been researching Celiac disease and Thiamine deficiency for a long time.  Recently I found information that shows a relationship between the lack of Thiamine and Celiac Disease pathogenesis.  What do you think? Thiamine is used in the mitochondria to produce energy (ATP) in the body for cells use as they go about their various functions.  Various chemical reactions take place as the glucose moves through the transport chain in the mitochondria.  Oxygen is needed at the end of the trans

knitty kitty

Thiamine Deficiency, Hypoxia, and Autoimmune Disease

Thiamine deficiency causes hypoxia.  Hypoxia-Inducible Factor 1α binds to thiamine transporter SLC19A3 and activates it to increase thiamine uptake.  HIF-1α signaling also triggers the release of inflammatory cytokines and inflammatory cells proliferation.  HIF-1a affects genes in the nucleus, entering through micro-pores.  Hypoxia and high levels of HIF-1a are found in many autoimmune diseases and cancer. "HIF-1α shows its functions through translocating into the nucleus, dimerizing with H

knitty kitty

Thiamine and Autoimmune Diseases

Thiamine and Autoimmune Diseases Human Leukocyte Antigens are coded for in our DNA.  They act like street signs on cells so the body knows that they are "Self".   Tissue typing in organ transplantation looks for donors with "Self" street signs similar to the recipient's in order to prevent rejection of the transplanted organ.   The HLA DQ genes code for immune cells.  Some immune cells are encoded to recognize certain protein strings when that protein string attaches to the receptor on

knitty kitty

Thiamine and Diabetes

People with diabetes may have genetic variations that cause their thiamine transporters to not absorb thiamine as well.  This functional thiamine deficiency can cause inflammation and diabetes.  Thiamine is needed to down regulate the inflammatory cytokines.   Genetic Variants of the Human Thiamine Transporter (SLC19A3, THTR2)—Potential Relevance in Metabolic Diseases https://pmc.ncbi.nlm.nih.gov/articles/PMC11988879/ Thiamine, gastrointestinal beriberi and acetylcholine sign

knitty kitty

Dairy and Celiac: studies

Bovine milk caseins and transglutaminase-treated cereal prolamins are differentially recognized by IgA of celiac disease patients according to their age https://pubmed.ncbi.nlm.nih.gov/19290628/   Gliadin and Casein Metabolism: Synthesis of Gliadomorphin and Casomorphin and Their Biological Consequences https://www.researchgate.net/publication/397908713_Gliadin_and_Casein_Metabolism_Synthesis_of_Gliadomorphin_and_Casomorphin_and_Their_Biological_Consequences   Effec

knitty kitty

Help!!

Took six-year-old two pediatrician complaining a frequent stomach aches. Did blood testing for celiac and she is IGA deficient. The next thing they tested for was tissue transglutaminase antibody igG and this came back positive with a normal range less than 15, her number was 87.9 so they referred us to a Gastro doctor. The gas doctor said that with this number there is a 99% chance of celiac, but they would like to do a scope to verify. We did a scope and everything looked good and they took sa

Amiah

Amiah in Celiac??

Inoculation day!

I did the hookworm larva collection and inoculation today. It took 1/2 hr with doing everything right and safely, including clean-up. You can see the 5 jars I prepared a week ago in the pic. Only #2 jar had a good number of larvae so it was the only jar I used. I placed enough drops onto a checker board scored Petri dish until I had 25 and soaked them up onto a gauze bandage. It wasn't worth the effort to pipette out one extra larva in the last drop so I ended up with 26 this time. Thi

dixonpete

dixonpete in Hookworms

My Story Chapter Two

My health declined when I was taking an SSRI.  I learned that certain drugs can cause Thiamine deficiency.  SSRI's are one of those drugs.  Depression is a symptom of Thiamine deficiency.  It's also a symptom of Vitamin D deficiency. I was eating the Standard American Diet at the time, which is a diet that causes High Calorie Malnutrition.  Consuming large amounts of carbohydrates without a corresponding increase in Thiamine causes a Thiamine deficiency.  For every extra 1000 calories an ad

knitty kitty

knitty kitty in My Journey

My Story

Yes, I do have Celiac disease.  I had symptoms since infancy, but they were explained away as character flaws.  I was told my stomach aches were faked to avoid going to school and other responsibilities, or to spoil family fun, and that my Dermatitis Herpetiformis was caused by being dirty and not bathing properly.  I wasn't diagnosed with Celiac until midlife. My various health problems for which I sought medical attention were treated as separate entities.  No medical professional looked

knitty kitty

knitty kitty in My Journey

Koikoi Trading Inc., Issues Allergy Alert on Undeclared Wheat and Sesame in FU ZHOU FISH BALL

Commerce, CA – Koikoi Trading Inc. is recalling certain lots of FU ZHOU FISH BALL products in multiple pack sizes (200g, 400g, and 5LB) because the products may contain undeclared allergens: wheat and sesame. People who have an allergy or severe sensitivity to wheat and/or sesame run the risk of a serious or life-threatening allergic reaction if they consume these products. The products were distributed through foodservice and e-commerce channels and may have reached consumers through direc

Scott Adams

Scott Adams in USA Recalls

About Celiac Remission

Exposure to gluten (and casein in those sensitive to it) can cause an increased immune response and inflammation for months afterwards.  The immune cells that make tTg IgA antibodies which are triggered today are going to live for about two years. During that time, inflammation is heightened.  Those immune cells only replicate when triggered.  If those immune cells don't get triggered again for about two years, they die without leaving any descendents programmed to trigger on gluten and cas

knitty kitty

Vitamins I Take

I like Life Extension Bioactive Complete B Complex.  It contains the easily activated forms of B vitamins needed by people with the MTHFR genetic variation often found with Celiac disease.   Avoid B Complex vitamins if they contain Thiamine Mononitrate if possible.  (Read the ingredients listing.)  Thiamine Mononitrate is the "shelf-stable" form of B 1 that the body can't utilize.  B vitamins breakdown when exposed to heat and light, and over time.  So "shelf-stable" forms won't breakdown s

knitty kitty

Nutrition and Gluten free diet

Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements https://pubmed.ncbi.nlm.nih.gov/10919966/ The effects of endurance training and thiamine supplementation on anti-fatigue during exercise https://pmc.ncbi.nlm.nih.gov/articles/PMC4241913/ Effects of thiamine supplementation on exercise-induced fatigue https://pubmed.ncbi.nlm.nih.gov/8815395/ Exploring the Relationship between Micronutrients and Athletic Performance: A Comprehensive Scie

knitty kitty

Gastrointestinal Beriberi

Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/#ref3 https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/#ref3 From Section 3: "In conclusion, TD limited to the gastrointestinal system may be an overlooked and underdiagnosed cause of the increasingly common gastrointestinal disorders encountered in modern medical settings. Left unattended, it may progress to wet or dry beriberi, most often observed as Wernicke e

knitty kitty

Häagen-Dazs Chocolate Dark Chocolate Mini Bars Recall Due to Undeclared Wheat and Gluten

Dreyer’s Grand Ice Cream, Inc. has issued a voluntary recall of certain Häagen-Dazs Chocolate Dark Chocolate Mini Bars due to undeclared wheat, which may pose a serious risk to those with wheat allergies or sensitivities. Product Details Product: Häagen-Dazs Chocolate Dark Chocolate Mini Bars (6-count) Batch code: LLA519501 Best By date: 31 JAN 2027 How to check: Look for batch code LLA519501 under “Best By 31 JAN 2027” on the package. Where Sold Kro

Scott Adams

Scott Adams in USA Recalls

Inoculation and video development

On September 23, 2025, I did my latest inoculation. It was right around the five-month mark — plenty of time to avoid the expected adult hookworm die-off in my gut at around 6 to 6.5 months. I never noticed any interruption of “worm services.” Neither my gluten reactions nor the colitis ever reared their ugly heads, so it appears I had a smooth transition with the new hookworms. This time, out of the five small jars I prepared, four were almost entirely vacant of larvae — but one was hoppin

dixonpete

dixonpete in Hookworms

Amy's Gluten-Free Burritos Recalled for Possible Foreign Material Contamination

Amy’s Kitchen has initiated a recall of select Gluten Free Bean & Rice Burritos due to potential foreign material, according to current recall listings. The affected retail unit is 5.5 oz with lot code 30C1725 and an expiration date of 03/2027. Distribution included multiple U.S. states. Specific foreign material was not disclosed in public summaries at the time of writing. Why This Matters for Celiac Disease and Gluten Sensitivity Gluten-free shoppers rely on accurate labeling and

Scott Adams

Scott Adams in USA Recalls

Doan’s Bakery Issues Allergy Update on Undeclared Wheat and Milk Allergens in Bundt Cakes

Doan’s Bakery of Woodland Hills, CA is recalling White Chocolate Coconut and Carrot Bundt Cakes because they may contain undeclared wheat and milk. People who have an allergy or severe sensitivity to wheat and/or milk run the risk of experiencing a serious or life-threatening reaction if they consume these products. The recalled bundt cakes were sold by Doan’s Bakery and distributed nationwide via mail order via goldbelly.comExternal Link Disclaimer from June 1, 2025 through September 24, 2

Scott Adams

Scott Adams in USA Recalls

Hookworms and ChatGPT5

I recently sprang for a ChatGPT5 subscription just to play with it and have found it to be a revelation. ChatGPT5 has become my new best friend helping me to explore and answer questions that have been nagging me sometimes for years. Of course our conversation turned to hookworms and celiac disease as well as my other condition, ulcerative colitis. ChatGPT5 had an awful lot to say on the topic and was able to summarize past research for me and tell me where future research is going. Here's

dixonpete

dixonpete in Hookworms

HEB Blueberry Flavored Yogurt Pretzels Recalled Due to Undeclared Wheat

Product Name: Blueberry Pretzels " Brand Name: HEB " Description: 8oz HEB Blueberry Flavored Yogurt Pretzels " UPC Codes: 9787011400 " Lot Numbers: 080226, 080326 " Best By / Use By Dates: 080226 & 080326 " Package Size: 8oz " Establishment Number: 008046575 " UPC Codes: 9787011400 " Lot Numbers: 080226, 080326 " Best By / Use By Dates: 080226 & 080326 " Package Size: 8oz " Establishment Number: 008046575 Read more at: www.accessdata.fda.gov  

Scott Adams

Scott Adams in USA Recalls

Just did the jars for the next hookworm incubation

Took about 20 minutes and 1/2 of that was clean-up. As per what has become my usual process, I prepared five small jars with the expectation of only using the one jar with the greatest population of larvae. Today is August 29th, so given that a week appears to be sufficient time for the eggs to hatch and the larvae to do their thing of migrating down to the water at the bottom of the jars, the harvest date will be Friday September 5th. This time I'll be having a crack at making a video for

dixonpete

dixonpete in Hookworms

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  • Blog Comments

    • knitty kitty

      Impairment of Thiamine Transport at the GUT-BBB-AXIS Contributes to Wernicke's Encephalopathy

      https://pubmed.ncbi.nlm.nih.gov/29128903/

    • Scott Adams

      You’re definitely connecting some real dots here, and your thinking isn’t off base—but it’s important to separate what’s established from what’s still theoretical.

      There is good evidence that HIF-1α and hypoxia-related pathways are involved in inflammation and are elevated in celiac disease tissue . And separately, thiamine deficiency can push cells toward anaerobic metabolism, increase lactate, and influence HIF-1α signaling. So biologically, your chain of reasoning—thiamine → energy metabolism → hypoxia signaling → inflammation—is plausible.

      Where it gets less certain is causation. Right now, the research doesn’t show that thiamine deficiency drives celiac disease. It’s more likely that:

      • celiac-related intestinal damage → malabsorption of nutrients (including thiamine)
      • inflammation → changes in metabolic and hypoxia pathways

      So thiamine deficiency may be more of a downstream effect or contributing factor, rather than a root cause.

      That said, your idea still has value. Even if it’s not causing celiac, low thiamine could:

      • worsen fatigue and brain fog
      • impact energy production
      • potentially amplify inflammatory signaling

      So optimizing thiamine status in people with celiac (especially untreated or newly diagnosed) could absolutely be beneficial—even if it’s supportive, not curative.

      The current evidence supports association and modulation, not direct causation of celiac disease.

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