Jump to content

  • You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Blood Test Results

Strunk15

Recommended Posts

Strunk15 Newbie
Strunk15
Posted

Hi everyone, I have been doing tons of reading to try to figure these numbers out, but am still confused, so thought I would turn to those of you who have been through this before.  I had a blood panel done, and the results came back:

  • Endomysial AB IGA- negative
  • Gliadin AB IGA- Negative:12 (flag reference being 0 - 15)
  • Anit-Gliadin IGG AB- Positive: 72.5 (flag reference being 0-15)
  • t-Transglutaminase IGG- Positive: 121.2 (flag reference range being 0-15)
  • t-Transglutaminase IgA- Negative: 12.5 (flag reference range being 0-15)
  • IGA- 158 (flag reference range 70-400)

From what I have read, I feel as if the results would indicate I do not have Celiac Disease, because I am not positive for IGA, but I don't seem to be deficient in it either.  Am I reading that totally wrong?  My PCP seemed confused by the numbers, but said that since the IGGs were high, it was indicative I had some sort of problem with gluten, and should therefore get an endoscopy.  I then went to the GI, who said we should go ahead with the endoscopy, but I still didn't get a sense from him as to if it was very necessary or if he was just going along with it because I was referred.  He didn't really explain what the lab results meant at all.

Based on the lab results, does anyone have a sense of if it makes sense to go through with an endoscopy?

Thank you so very much for any assistance!  I am driving myself crazy trying to figure this out!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Strunk15 Newbie
Strunk15
Posted
  • Author

I guess more generally, my question is, can someone with Celiac have positive IGG, but negativite IGA (without being IGA deficient)?

cyclinglady Grand Master
cyclinglady
Posted

I think then answer is yes.  I am no expert, but your doctors are following protocol per the GI Association.  Get a positive, next step biopsies.  I personally tested positive only to the DGP IGA but negative on the rest (same for follow-up testing, so it was not a fluke), yet I had a Marsh Stage IIIB.  I would get the biopsies.  Oh, did I mention that I had anemia and no tummy issues at the time of my diagnosis?  Believe me I was shocked!  I just went in for a GI consult for a colonoscopy because I joined the 50's club!  ?

bookbeast Newbie
bookbeast
Posted

Hi. I was just diagnosed with Celiac's after the doctor did an endoscopy. Now to confirm my diagnosis, I have to do a colonoscopy to get a biopsy of the small intestine to confirm Celiac's, so what I would suggest is forget the endoscopy because they can't get to you small intestine from there. Do a colonoscopy. I recommend it. I'm doing mine soon to confirm, and from what I read online, that's how one can know for sure is through a biopsy. Blood tests aren't fool proof. Good luck. 

cyclinglady Grand Master
cyclinglady
Posted

Forgot this link stating it is possible to have celiac disease with a positive IGG and not be IGA deficient.  

Open Original Shared Link

 

cyclinglady Grand Master
cyclinglady
Posted
1 hour ago, bookbeast said:

Hi. I was just diagnosed with Celiac's after the doctor did an endoscopy. Now to confirm my diagnosis, I have to do a colonoscopy to get a biopsy of the small intestine to confirm Celiac's, so what I would suggest is forget the endoscopy because they can't get to you small intestine from there. Do a colonoscopy. I recommend it. I'm doing mine soon to confirm, and from what I read online, that's how one can know for sure is through a biopsy. Blood tests aren't fool proof. Good luck. 

No, the endoscopy (obtaining four to six  tissue samples) is the gold standard per most medical research (University of Chicago's Celiac Website is one source).  Your doctor may want to check out yor colon (e.g. Rule out Chrohns) and it is possible to biopsy the lower end of the small Intestine.  

Strunk15 Newbie
Strunk15
Posted
  • Author

Thank you for the info!  I also don't really have stomach symptoms.  My doctor just tested me due to me having extreme tiredness.  Now looking at the list of symptoms, I also see I have some other things that can indicate celiac, such as I was extremely short and had muscle weakness as a child.  I also have brain fog, etc.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


frieze Community Regular
frieze
Posted

book, you definitely need to clarify with doc about scoping....

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      134,077
    • Most Online (within 30 mins)
      10,442
    terrificterry
    Newest Member
    terrificterry
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      Sigh. I posted this yesterday based on the Safeway website. I went back again today to their website to double check. On the page where they are selling Vanilla Bean flavor, it has a distinct Certified Gluten Free label. Other flavors on the Safeway website didn't have the gluten-free statement. Today I went into the store. None of the flavors I looked at, including Vanilla Bean, have a Gluten Free statement. Is it safe? Who knows. The ingredients are either safe or nearly safe (some have "natural flavor"). There are warnings about "contains milk and soy" but not about wheat - this implies they are safe, but again, who knows. On the other hand, every flavor I checked of their Slow Churn line of ice creams has wheat as an ingredient. 100% not safe.
    • knitty kitty
      Edy's and Dreyer's ice cream

      By knitty kitty · Posted

      Do keep in mind that many of the newly diagnosed have lactose intolerance.  This is because the villi lining the intestinal tract are damaged, and can no longer make the enzyme lactAse which breaks down the milk sugar lactOse.  When the villi grow back (six months to two years), they can again produce the enzyme lactAse, and lactose intolerance is resolved.  However, some people (both those with and without Celiac Disease) are genetically programmed to stop producing lactase as they age.   Do be aware that many processed foods, including ice cream, use Microbial Transglutaminase, a food additive commonly called "meat glue," used to enhance texture and flavor.  This microbial transglutaminase has the same immunogenicity as tissue transglutaminase which the body produces in response to gluten in people with Celiac Disease.  Tissue Transglutaminase (tTg IgA) is measured to diagnose Celiac Disease in blood tests.  Microbial Transglutaminase acts the same as Tissue Transglutaminase, causing increased intestinal permeability and inflammation.   New findings show that microbial transglutaminase may be able to trigger Celiac Disease and other autoimmune and neurodegenerative diseases.   Microbial Transglutaminase is not required to be listed on ingredients labels as it's considered a processing aid, not an ingredient in the U.S.  Microbial Transglutaminase has been GRAS for many years, but that GRAS standing is being questioned more and more as the immunogenicity of microbial transglutaminase is being discovered. Interesting Reading:  Microbial Transglutaminase Is a Very Frequently Used Food Additive and Is a Potential Inducer of Autoimmune/Neurodegenerative Diseases https://pmc.ncbi.nlm.nih.gov/articles/PMC8537092/
    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      There is a 10 year old post in this forum on Edy's and Dreyer's ice cream. The information is somewhat outdated and the thread is closed to further comment, so here is a new one. Edy's And Dreyer's Grand Vanilla Bean Ice Cream - 1.5 Quart is labeled "Gluten Free". This is a different answer than years gone by. I don't know the answer for any other flavor at this moment. On 1 May, 2026, Edy's website says: "As a general rule, the gluten in Edy's and Dreyer's® frozen dessert products is present only in the added bakery products, such as cookies, cake or brownies. We always label the eight major food allergens on our package by their common name. We recommend to always check the label for the most current information before purchasing and/or consuming a product. The exception to this rule is our Slow Churned French Silk frozen dairy dessert, which contains gluten in the natural flavors." https://www.icecream.com/us/en/brands/edys-and-dreyers/faq It seems that Edy's and Dreyer's are more celiac-friendly than they were 10 years ago. Once I found enough information to make today's buying decision, I stopped researching.
    • Aretaeus Cappadocia
      EDG 3 years ago fine, now it shows focal villous blunting,

      By Aretaeus Cappadocia · Posted

      probably not your situation @Mimiof2, but allow me to add one more to @trents list of celiac-mimics: "olmesartan-induced sprue-like enteropathy"  
    • knitty kitty
      Terrible Neurological Symptoms

      By knitty kitty · Posted

      My dad had an Abdominal Aortic Aneurysm.  Fortunately, it was discovered during an exam.  The doctor could feel my dad's heart beating in his stomach/abdomen.  The aneurysm burst when the doctor first touched it in surgery.  Since he was already hooked up to the bypass machine, my dad survived ten more years.  Close call! Triple A's can press on the nerves in the spinal cord causing leg pain.  I'm wondering if bowing the head might have increased the pressure on an aneurysm and then the nerves.   https://gulfcoastsurgeons.com/understanding-abdominal-aortic-aneurysm-symptoms-and-causes/ Abdominal Aortic Aneurysm Presenting as a Claudication https://pmc.ncbi.nlm.nih.gov/articles/PMC4040638/
×
×
  • Create New...