Jump to content
  • Sign Up
  • Join Our Community!

    Do you have questions about celiac disease or the gluten-free diet?

Scott Bonner

Lactulose/mannitol Test For Leaky Gut

Rate this topic

Recommended Posts

Hi, everyone. I'm brand new to the forum. I have a question for you. (I've searched the forums for a topic that might already have answers to my question, but could not find one.)

Have any of you had a lactulose/mannitol test to determine whether or not you have a leaky gut? I just got the results back from my test, and it's pretty scary. The percentage of lactulose recovered in my urine was 2.45. That's much higher than normal. The percentage of mannitol recovered was 26, which is also quite high. The lactulose/mannitol ratio was .09, again fairly high.

I'm just curious if any of you have had this test done and, if so, how your results compare to mine.

I have not (yet) been diagnosed with celiac disease, but I am almost certain I have it. After elminating gluten (and casein) from my diet 10 months ago, my depression/anxiety cleared up completely. It was amazing. I've been on the paleo diet (lean meat, fresh fruit and vegetables) ever since, and haven't had any problems. Except for eczema and shortness of breath after eating citrus fruits and tree nuts -- and so I've elminated them as well.

I've asked my doctor (a family practitioner) if he can find another lab that will perform this same test. I just want to confirm the results. If confirmed, I guess I'll start looking for ways to heal the gut -- I've heard glutamine, fish oil, and acidophilus are all helpful. Any other treatments you've heard of?

Thanks much!

Scott

Share this post


Link to post
Share on other sites

Hi Scott, just wanted to welcome you to the boards. I have not had that test but it seems like something I should look into.

Share this post


Link to post
Share on other sites

I had the test several years ago. I will be having a new test in a couple of weeks.

Glutamine is said to be the best 'gut' healer. It worked for me but I am no longer allowed to take it so I will probably have problems again. Claire

Share this post


Link to post
Share on other sites
I had the test several years ago. I will be having a new test in a couple of weeks.

Glutamine is said to be the best 'gut' healer. It worked for me but I am no longer allowed to take it so I will probably have problems again. Claire

Claire, do you mind if I ask why you're no longer able to take it? Did you develop some type of allergy to it?

Thanks,

Scott

Share this post


Link to post
Share on other sites

I have heard of the test, seems like it is growing in popularity for its ability to measure intestinal effects in individuals w/o classic biopsy or w/o being invasive...

Share this post


Link to post
Share on other sites
Have any of you had a lactulose/mannitol test to determine whether or not you have a leaky gut? I just got the results back from my test, and it's pretty scary. The percentage of lactulose recovered in my urine was 2.45. That's much higher than normal. The percentage of mannitol recovered was 26, which is also quite high. The lactulose/mannitol ratio was .09, again fairly high.Scott

Welcome Scott-

I'm pretty new also 6 months gluten-free and now trouble with dairy and my chiropractor thinks I have leaky gut. still trying to wrap my head around what that is...I'm embarrased to say I don't know what mannitol is??

Can you help me here so I don't have to do a search?

Does the dr have to order the test?

I feel that acidophilus is so helpful for me been taking it for many years.

Thanks much!

Judy in Philly

Share this post


Link to post
Share on other sites

Hope the following will be of help:

Causes of Leaky Gut Syndrome / Intestinal Permeability

• Chronic stress

• Intestinal infections

• Small intestine bacterial overgrowth

• Environmental contaminants

• Excess alcohol

• Poor diet

• NSAIDS and other medications

Testing

The standard test for leaky gut syndrome is the mannitol and lactulose test. Both are water soluble molecules that the body can't use. Mannitol is easily absorbed by people with healthy intestinal linings. Lactulose is a larger molecule and is only slightly absorbed. A person drinks a solution contain both mannitol and lactulose. Urine is collected for six hours and the amount present in urine reflects how much was absorbed by the body. A healthy test shows high levels of mannitol and low levels of lactulose. If high levels of both molecules are found, it indicates a leaky gut condition. If low levels of both molecules are found, it indicates general malabsorption of all nutrients.

Source http://altmedicine.about.com/od/healthcond...estLeakyGut.htm

This article fails to mention Celiac -i.e. gluten - as a cause of LGS. Big omission!

As you can see here - this test also will show malabsorption - probably more accurately than some of the lab tests do.

A GI specialist can order the test. Some GPs will also - if they happen to know what it is.

Scott: to answer your question: I stopped taking L-glutamine because the glutamates are iffy for people with neurological problems - specifically cerebellar damage. As I have cerebellar ataxia this product was discontinued. In cases of cerebellar damage it is uncertain whether the brain will or will not process glutatmates properly. I am being on the safe side. Claire

Share this post


Link to post
Share on other sites

Thanks so very much Claire and Jen

Judy in Philly :)

Share this post


Link to post
Share on other sites

Where can I have the lactulose/mannitol test for leaky gut syndrome performed? I'm in Akron, Ohio, but willing to travel if necessary. My physician told me any gastroenterologist could order this test, then her staff referred me to a gastroenterologist who didn't know this test existed.

Share this post


Link to post
Share on other sites

Where can I have the lactulose/mannitol test for leaky gut syndrome performed? I'm in Akron, Ohio, but willing to travel if necessary. My physician told me any gastroenterologist could order this test, then her staff referred me to a gastroenterologist who didn't know this test existed.

Just an FYI - this thread is from 2006. I don't think any of these members have been on in a few years.

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.


  • Top Posters +

  • Upcoming Events

    • April 17, 2019 Until April 27, 2019
      0  
      April 17-27, 2020   For the past few years many of you have asked us to arrange a River Boat Cruise that will allow us to visit Amsterdam's famous Keukenhof Gardens at its prime time of the blossoming of the millions of Tulips and Hyacinths - alongside the windmills of the Netherlands.  With the participation of a minimum of 20 persons we have arranged an All-Inclusive Cruise from Antwerp to Amsterdam.  This cruise will not be offered to the public until January, 2019 and always sells out quickly.   THERE WILL BE NO MONEY REQUIRED NOR COMMITMENT FROM YOU until we have all the final costs and details.  If you are at all interested check out our website for as many of the details that we have as of this time.   We need your request to be placed on a list of interested participants so we can present that number to Uniworld to show we have the sincere interest in this All-Inclusive Bob & Ruth's Gluten-free Cruise.   PLEASE CHECK OUT OUR WEBSITE FOR THE DETAILED INFORMATION THAT WE HAVE AS OF THIS TIME.   http://bobandruths.com
    • April 24, 2019 04:00 PM Until 08:00 AM
      0  
       
       
       
      Celiac Emotional Healing Support Group
       
       
       
      Again you are invited to join Johnny Patout, LCSW for Baton Rouge's first emotional healing support group meeting to assist those living with celiac disease manage the emotional challenges so many of us face. Most often the emotional disturbances include depression, disinterest in normal activities, insomnia, grief, mood changes, anxiety, inability to concentrate, extreme concern about managing a gluten-free lifestyle and other emotional and behavioral challenges.
       
      The professionals at Jamestown Avenue Counseling Center created the emotional healing support group to give us a safe place to begin to process our emotions and support each other as we heal emotionally while managing celiac disease and the resulting autoimmune disorders.
       
      The emotional healing support group meets every Thursday, 6:00-7:00pm, at the Jamestown Avenue Counseling Center of Baton Rouge. Jamestown Avenue Counseling Center is located at 4637 Jamestown Avenue, Baton Rouge, Suite B-1. Suite B-1 is upstairs.
       
      The support group is free and open everyone managing celiac disease. For more information: emotionalhealingforceliacs@hotmail.com
    • May 04, 2019 Until May 05, 2019
      0  
      Nourished Festival is a family-friendly event with 10 locations across the US. Attendees will be able to sample food, health and beauty products, meet with companies, learn about the most current food lifestyles, receive coupons and attend educational sessions with industry experts. 
      Nourished Festival, managed by The Nourished Group and presented by Enjoy Life Foods, is the largest gluten-free, allergy-friendly and specialty diet event in the US, with 10 locations including.
      ABOUT THE NOURISHED FESTIVALS
      Managed by The Nourished Group, formerly The Gluten Free Media Group, The Nourished Festivals are the largest and fastest growing special diet consumer events in the United States. Started in 2007, the events have expanded from one to ten cities throughout the country. The festivals cater to anyone looking to lead a healthier lifestyle or those who follow a specialty diet due to autoimmune conditions, food sensitivities, allergies or intolerances. Offerings including Paleo, Keto, Plant-Based, Gluten-Free, Allergen-Friendly and Nut-Free products. The events provide the opportunity for attendees to sample and purchase new products, receive coupons, meet with brand ambassadors and attend educational classes with industry experts. For more information, visit http://www.nourishedfestival.com 
       
×
×
  • Create New...