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What's the difference between gliadin testing and tissue transglutaminse test?


Happy families

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Happy families Rookie

Hi. Just got my blood test report emailed thru. Can anyone help me what the difference between gliadin testing and tissue transglutaminase test is? See attached pic. I have continual low iron that I have had transfusion for. I'm back down to 35. Ceoliac is in my family. I only started gluten a week or so before my blood test. Otherwise I didn't eat much of it. Wasn't strictly gluten free but didn't eat much of it. 

Screenshot_20211103-113405_Word.webp


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Scott Adams Grand Master

Welcome to the forum! The tissue transglutaminase test is considered the most accurate one for adults, but really, each test that was done, including the Deamidated Gliadin tests are very accurate as well.

Were you eating gluten daily before the tests? Also, did your doctor schedule an endoscopy based on your positive result?

This article is a bit older, but does explain some of these tests:

 

Happy families Rookie
7 hours ago, Scott Adams said:

Welcome to the forum! The tissue transglutaminase test is considered the most accurate one for adults, but really, each test that we given you, including the Deamidated Gliadin tests are very accurate as well.

Were you eating gluten daily before the tests? Also, did your doctor schedule an endoscopy based on your positive result?

This article is a bit older, but does explain some of these tests:

 

Thankyou.  I'll have a read. I was only eating gluten properly for about a week or 2 prior to the blood test. Was scheduled for biopsy next week but gastro Dr wants me to wait another 3 weeks and do blood test again so I have been on gluten for longer. The more gluten a person eats the more the levels go up if it's ceoliac? 

Scott Adams Grand Master

Yes, technically you need to eat around 2 slices of bread per day for 6-8 weeks in order for the blood test results to be accurate. Given the one positive result it's likely a good idea to do this challenge to see what the levels are after you've been eating gluten for the proper time period.

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