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Ok.. do I have this right? I have tested positive for DQ2 and DQ8, but have had a negative antibody test. So, this means that I am not currently reacting to gluten, but COULD develop celiac at any time in my life? Also, do I understand that I got DQ2 from one parent and DQ8 from my other parent ? If this is so, then am I correct in saying that both of my parents are "at risk" as well?

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I believe you have it correct.

Does this also mean that because I carry both genetic markers, DQ2/DQ8 that both of my children will have at least one of the markers? Either DQ2 or DQ8 plus another marker from their father?

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Does this also mean that because I carry both genetic markers, DQ2/DQ8 that both of my children will have at least one of the markers? Either DQ2 or DQ8 plus another marker from their father?

As I understand it, no. Your children could inherit both, only one, or neither one. I believe that the probability of getting at least one is 75%, not 100%.

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So, this means that I am not currently reacting to gluten, but COULD develop celiac at any time in my life?

That depends, are you having symptoms? If you are you need to know that there are high rates of false negatives with the blood tests and even with the endo. If you are symptomatic, including fatigued, anemia, skin problems, issues with moods, fibro etc as well as, or instead of, GI issues you could still have an issue with gluten and a gluten-free trial after all testing would be in order.

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That depends, are you having symptoms? If you are you need to know that there are high rates of false negatives with the blood tests and even with the endo. If you are symptomatic, including fatigued, anemia, skin problems, issues with moods, fibro etc as well as, or instead of, GI issues you could still have an issue with gluten and a gluten-free trial after all testing would be in order.

Thanks! Yes, I believe I am having non-GI symptoms. My antibody test came back neg. but my genetic test is pos for DQ2/DQ8. I have made an appointment to see a GI specialist to set up a biopsy. My son has already been diagnosed with celiac via a biopsy and pos. antibody test. My daugter has had no testing done yet. This is all pretty recent in my family. I have made an appointment to have an antibody test for her, but didn't feel it was needed to have a genetic test being as I have already tested pos. on that end. I dont really feel that my family doctor knows enough about celiac disease to give me specific/accurate info...thanks for the info.

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Thanks! Yes, I believe I am having non-GI symptoms. My antibody test came back neg. but my genetic test is pos for DQ2/DQ8. I have made an appointment to see a GI specialist to set up a biopsy. My son has already been diagnosed with celiac via a biopsy and pos. antibody test. My daugter has had no testing done yet. This is all pretty recent in my family. I have made an appointment to have an antibody test for her, but didn't feel it was needed to have a genetic test being as I have already tested pos. on that end. I dont really feel that my family doctor knows enough about celiac disease to give me specific/accurate info...thanks for the info.

Be sure to give the diet a try after all testing is done. No matter what the results.

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