Jump to content

  • You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Help With Results

learningaboutceliac

Recommended Posts

learningaboutceliac Newbie
learningaboutceliac
Posted

Hello,

I recently had a scope to determine reasons for weight loss, fatigue, bloating, and dry itchy skin and psorasis. I obtained the lab results today but am unable to meet with the doctor until after the holidays. Could someone please help me interpret the results.

Biopsises of duodenum

-marked increase in intraepithelial lymphocytes

Comment: Sections from duodenum show marked increase in intraephithelial lymphocytes and expansion of lamina propria by mononuclear inflammatory infiltrate. Focal minimal activity and crypt abscess is also noted. Villous blunting is noted in well oriented duodenal villi. Clinical and serological correclation is recommeded to rule out Celia disease. H. pylor micro-organisms are nto identifed on routine stains in sections examined.

Biposies of gastric antrum:

-gastric antrum and body type mucosa with mild chronic gastritis

-negative for intestinal metaplasia, dysplasis or malignancy

-negative for H. pylori micro-organisms on routine and special stains

I also have vitilogo. It was my understanding that biopsy would be the determining factor for a diagnosis of Celiac, so am confused about the recommendation for bloodwork.

Thanks in advance.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mushroom Proficient
mushroom
Posted

Hello,

I recently had a scope to determine reasons for weight loss, fatigue, bloating, and dry itchy skin and psorasis. I obtained the lab results today but am unable to meet with the doctor until after the holidays. Could someone please help me interpret the results.

Biopsises of duodenum

-marked increase in intraepithelial lymphocytes

Comment: Sections from duodenum show marked increase in intraephithelial lymphocytes and expansion of lamina propria by mononuclear inflammatory infiltrate. Focal minimal activity and crypt abscess is also noted. Villous blunting is noted in well oriented duodenal villi. Clinical and serological correclation is recommeded to rule out Celia disease. H. pylor micro-organisms are nto identifed on routine stains in sections examined.

Biposies of gastric antrum:

-gastric antrum and body type mucosa with mild chronic gastritis

-negative for intestinal metaplasia, dysplasis or malignancy

-negative for H. pylori micro-organisms on routine and special stains

I also have vitilogo. It was my understanding that biopsy would be the determining factor for a diagnosis of Celiac, so am confused about the recommendation for bloodwork.

Thanks in advance.

Yes, the biopsy has always been considered the 'gold standard' of celiac diagnosis, but it sounds like you are in the early stages and the pathologist who read your slides was not totally convinced. Everything I have bolded is indicative of celiac disease. He is suggesting that your doctor run the celiac blood panel for confirmation of celiac.

For now, you can enjoy the holiday food as much as you can because these might be your last glutenous holidays :D

learningaboutceliac Newbie
learningaboutceliac
Posted
  • Author

Yes, the biopsy has always been considered the 'gold standard' of celiac diagnosis, but it sounds like you are in the early stages and the pathologist who read your slides was not totally convinced. Everything I have bolded is indicative of celiac disease. He is suggesting that your doctor run the celiac blood panel for confirmation of celiac.

For now, you can enjoy the holiday food as much as you can because these might be your last glutenous holidays :D

Thank you very much for your response.

My doctor has been trying to find the source of the fatigue, weight loss, etc (along with a B12 deficiency and anemia), so while I am not thrilled about the possible celiac diagnosis, I understand that there are far worse alternatives. Lymphoma has been ruled out after I had a CT scan that was negative after enlarged lymph nodes were detected on MRI.

I will enjoy the festive holiday treats and have the blood tests in the new year!

nvsmom Community Regular
nvsmom
Posted

Good luck with your blood tests; I hope you get clear results. :)

  • 1 month later...
learningaboutceliac Newbie
learningaboutceliac
Posted
  • Author

Hello again,

Firstly, I would like to thank everyone who has ever written a post on this site. I feel like I have read them all and am astounded by the depth and breadth of knowledge!

I had a follow up visit today with my doctor. Blood test (ttg IgA) results confirm diagnosis of Celiac Disease, following biopsy. Lab result was >80 with <4 being the reference range.

Additional blood tests showed elevated Red Blood cells (17.3 with reference range 11-14.5), elevated ESR (20 with reference range 0-12), Low RBC folate (319 with reference range of >829, and low ferritin (10 with reference range of 11-145).

I currently take B12 shots every three weeks. He has suggested 5 mg of folic acid. He didn't check my iron, so I am going tomorrow to have that blood test performed. Other then the folic acid, is there anything else he should be recommending. He self admitted that he does not know much about Celiac Disease and has referred me to a GI.

I have now been on a gluten free diet for 5 weeks. I am encouraged that I am seeing some small improvements..... less gastrointestinal issues, more restful sleep, gained 4 pounds :)

beachbirdie Contributor
beachbirdie
Posted

Hey learningabouceliac!

Thanks for thinking to post an update. I'm so glad to hear you have a definitive answer, and it sounds like you are on your way to healing!

Cheers!

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      134,083
    • Most Online (within 30 mins)
      10,442
    Melvac
    Newest Member
    Melvac
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      Sigh. I posted this yesterday based on the Safeway website. I went back again today to their website to double check. On the page where they are selling Vanilla Bean flavor, it has a distinct Certified Gluten Free label. Other flavors on the Safeway website didn't have the gluten-free statement. Today I went into the store. None of the flavors I looked at, including Vanilla Bean, have a Gluten Free statement. Is it safe? Who knows. The ingredients are either safe or nearly safe (some have "natural flavor"). There are warnings about "contains milk and soy" but not about wheat - this implies they are safe, but again, who knows. On the other hand, every flavor I checked of their Slow Churn line of ice creams has wheat as an ingredient. 100% not safe.
    • knitty kitty
      Edy's and Dreyer's ice cream

      By knitty kitty · Posted

      Do keep in mind that many of the newly diagnosed have lactose intolerance.  This is because the villi lining the intestinal tract are damaged, and can no longer make the enzyme lactAse which breaks down the milk sugar lactOse.  When the villi grow back (six months to two years), they can again produce the enzyme lactAse, and lactose intolerance is resolved.  However, some people (both those with and without Celiac Disease) are genetically programmed to stop producing lactase as they age.   Do be aware that many processed foods, including ice cream, use Microbial Transglutaminase, a food additive commonly called "meat glue," used to enhance texture and flavor.  This microbial transglutaminase has the same immunogenicity as tissue transglutaminase which the body produces in response to gluten in people with Celiac Disease.  Tissue Transglutaminase (tTg IgA) is measured to diagnose Celiac Disease in blood tests.  Microbial Transglutaminase acts the same as Tissue Transglutaminase, causing increased intestinal permeability and inflammation.   New findings show that microbial transglutaminase may be able to trigger Celiac Disease and other autoimmune and neurodegenerative diseases.   Microbial Transglutaminase is not required to be listed on ingredients labels as it's considered a processing aid, not an ingredient in the U.S.  Microbial Transglutaminase has been GRAS for many years, but that GRAS standing is being questioned more and more as the immunogenicity of microbial transglutaminase is being discovered. Interesting Reading:  Microbial Transglutaminase Is a Very Frequently Used Food Additive and Is a Potential Inducer of Autoimmune/Neurodegenerative Diseases https://pmc.ncbi.nlm.nih.gov/articles/PMC8537092/
    • Aretaeus Cappadocia
      Edy's and Dreyer's ice cream

      By Aretaeus Cappadocia · Posted

      There is a 10 year old post in this forum on Edy's and Dreyer's ice cream. The information is somewhat outdated and the thread is closed to further comment, so here is a new one. Edy's And Dreyer's Grand Vanilla Bean Ice Cream - 1.5 Quart is labeled "Gluten Free". This is a different answer than years gone by. I don't know the answer for any other flavor at this moment. On 1 May, 2026, Edy's website says: "As a general rule, the gluten in Edy's and Dreyer's® frozen dessert products is present only in the added bakery products, such as cookies, cake or brownies. We always label the eight major food allergens on our package by their common name. We recommend to always check the label for the most current information before purchasing and/or consuming a product. The exception to this rule is our Slow Churned French Silk frozen dairy dessert, which contains gluten in the natural flavors." https://www.icecream.com/us/en/brands/edys-and-dreyers/faq It seems that Edy's and Dreyer's are more celiac-friendly than they were 10 years ago. Once I found enough information to make today's buying decision, I stopped researching.
    • Aretaeus Cappadocia
      EDG 3 years ago fine, now it shows focal villous blunting,

      By Aretaeus Cappadocia · Posted

      probably not your situation @Mimiof2, but allow me to add one more to @trents list of celiac-mimics: "olmesartan-induced sprue-like enteropathy"  
    • knitty kitty
      Terrible Neurological Symptoms

      By knitty kitty · Posted

      My dad had an Abdominal Aortic Aneurysm.  Fortunately, it was discovered during an exam.  The doctor could feel my dad's heart beating in his stomach/abdomen.  The aneurysm burst when the doctor first touched it in surgery.  Since he was already hooked up to the bypass machine, my dad survived ten more years.  Close call! Triple A's can press on the nerves in the spinal cord causing leg pain.  I'm wondering if bowing the head might have increased the pressure on an aneurysm and then the nerves.   https://gulfcoastsurgeons.com/understanding-abdominal-aortic-aneurysm-symptoms-and-causes/ Abdominal Aortic Aneurysm Presenting as a Claudication https://pmc.ncbi.nlm.nih.gov/articles/PMC4040638/
×
×
  • Create New...