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Phenylephrine Hcl

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I called McNeil the makers of Tylenol about Tylenol sinus congestion & pain sever, they said the old is gluten free, the new one with phenylephrine hcl has not been tested. Today I've had 2 coffee (less than usual)and my aciphex, was feeling fine, I took the above and now my gut is pulsating ,I'm real jittery. I looked up manufacturers of phenylephrine hcl and of course there are some in china. China, that's all I need to run to the hills. When they say they haven't tested it yet, I don't understand, I'm A contractor and there level of customer service sucks! I guess I'll just go to pirate mode and walk around growling, GRRRRRRRRRRRRRRRRRRRRRRRRR. <_< AH HELL I'm out of here , I'm going fishing. My thoughts are going wild now. Anyone else?

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You may be reacting to the Phenylephrine HCl itself. It is a vasoconstrictor which has an effect on the entire body when taken orally. As the blood vessels tighten up, your blood pressure rises, and a stimulant action also occurs.


Diagnosis by biopsy of practically non-existent villi; gluten-free since July 2000. I was retested five years later and the biopsy was normal. You can beat this disease!

Type 1 (autoimmune) diabetes diagnosed in March 1986

Markham, Ontario (borders on Toronto)

Celiac.com - Celiac Disease Board Moderator since 2007

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I just found this and wanted to add that any amount of caffeine (even though it is less than you usually drink) will increase the stimulant effects of phenylephrine. Some people are also just sensitive to the effects of the medication - increased heart rate, "jittery" feeling, increased blood pressure. I took it once and when I couldn't sit still I checked my pulse rate - 190 while sitting down relaxing! If you take this medication again take it without the caffeine and perhaps cut the dose in half. I know it can be rough to cut out the coffee and soda (especially if you drink them daily) but they are also bad for you when you're sick. The best thing you can do is drink LOTS of water, it'll keep you hydrated.

I'm sorry they've been so sketchy about the details of whether the medication contains gluten, but it sounds to me more like a reaction to the medication itself than to gluten. Let us know what you find!


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I would agree with a reaction to Phenylephrine HCl ....even more so caffiene + Phenylephrine HCl because they have an additive effect - the combination is more potent than either drug taken alone. Yes, caffiene is a drug - a CNS stimulant to be exact.

See the following - listed side effects from each:

Phenylephrine Hydrochloride :

May give rise to a wide range of effects :

Central nervous system ; anxiety, fear, restlessness, tremor, irritability, confusion and

weakness, headache, sedation varying from slight drowsiness to deep sleep.

Cardiovascular system ; tachycardia, cardiac arrhythmias, angina pectoris, palpitations,

hypertension, hypotension with dizziness, and dyspnoea.

Other side effects; altered metabolism including glucose metabolism, nausea and vomiting,

diarrhoea and constipation, anorexia or increased appetite, and difficulty with micturition.

Caffeine :

May cause nausea, vomiting, abdominal pain, gastrointestinal bleeding, insomnia, headache,

anxiety, restlessness, vertigo and palpitations.

Note** many could cold meds contain caffeine too - so.... combine the meds plus coffee = more likely to have side effects



Type 1 diabetes - 1986

hypothyroid -1993

pernicious anemia

premature atrial beats



daughter is: age 15

central hypotonia and developmental delay

balance issues (rides an adult 3 wheel bike)

hypothyroid 1996

dermatographia - a form of angioedema 2002

celiac 2004 - by endoscopy

diagnosed Aspergers at age 7 - responded very well (HUGE difference) to gluten-free diet

recovered from Kawasaki (2003)

lactose intolerant - figured out in Oct/06

Gilberts syndrome (April/07)

allergy to stinging insects

scoliosis Jan 2008

nightshade intolerance - figured out April 2008

allergy to Sulfa antibiotics

son is 13

type 1 diabetic - 2003 diagnosed on his 9th birthday

celiac - 2004 by endoscopy

lactose intolerant - figured out Nov/06

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