Stress events that can lead to diagnosis

[Debra Krause]

I am trying to find an article or two about a situation, or disruption in life, or stress causing the onset of celiac disease.  I know, in the past, that I had read about things that trigger the onset of celiac disease.  My granddaughter is real thin and has lost 6 pounds.  Her blood test was negative.  This covid-19 crisis has affected her and she is very anxious about the virus all the time.  I need to show my daughter articles that cover the above.  I was diagnosed at age 46, now am 66.  My other daughter was diagnosed at 9 years old, now 41, her son was diagnosed at 13, now 16.  My granddaughter that I am most concerned about now turned 10 yesterday.  Her mom, my second daughter, has serious gas problems, but is in denial.  I hope that you can guide me to the articles on how some upset in life can trigger this disease, especially in a family such as ours with celiac disease diagnoses.  Thank you!

[cyclinglady]

Welcome!  
 

No one knows for sure exactly what triggers celiac disease.  Doctors suspect stress or an infection (virus or bacteria), but nothing has been proven.  
 

For a while it was thought that first-degree relatives had a 1 in 10 chance of developing celiac disease (if they have the genes to do so).  Recently, Mayo Clinic published a study on relatives and the risk of celiac disease and they found a  44% chance!  Almost 50-50!  Yikes!  Of those, 94% had NO symptoms.  
 

https://www.news-medical.net/news/20190822/Mayo-Clinic-Study-Calls-For-Screening-Of-Family-Members-Of-Celiac-Disease-Patients.aspx
 

Did your granddaughter get a complete celiac disease blood test panel (DGP, TTG and EMA tests?  Was she tested to see if she was Immunoglobulin A (IgA) deficient (it is used as a control test for the celiac tests ending in IgA (e.g. TTG IgA test)?  I bring this up because she is young.  While the TTG test is very good, it does not catch all celiacs, especially in kids.  The DGP tests are better.  Me?  I never had a positive TTG test (repeated many times) yet had a positive on the DGP IgA and I am biopsy confirmed.  My GI ordered the complete panel.  But when I asked family members to get tested, they got only the TTG tests.  They had to go back and ask for the complete panel.  
 

Know too that about 10% of celiacs are seronegative.  

https://celiac.org/about-the-foundation/featured-news/2017/05/diagnostic-approaches-identifying-celiac-disease/

i thought  for sure my niece had celiac disease, but she had the complete panel and an endoscopy.  Celiac disease, for now was firmly ruled out.  However, still having problems, her 4th GI ordered a pill camera and caught the damage from Crohn’s.  Lesson?  Never give up.  

 

Autoimmune disease runs rampant in my family — all sides.  Consider ruling out Type 1 diabetes since she is losing weight.  
 

Good reputable information can be found at all the celiac disease research centers (e.g. University of Chicago) or organizations (e.g. Beyond Celiac .org or the celiac disease Foundation or National Celiac Disease Association).  This might be helpful when convincing your bloated daughter to get help for herself or your granddaughter.  But know, some people can not imagine giving up gluten.  

 

 

[Awol cast iron stomach]

13 hours ago, cyclinglady said:

For a while it was thought that first-degree relatives had a 1 in 10 chance of developing celiac disease (if they have the genes to do so).  Recently, Mayo Clinic published a study on relatives and the risk of celiac disease and they found a  44% chance!  Almost 50-50!  Yikes!  Of those, 94% had NO symptoms.  
 

https://www.news-medical.net/news/20190822/Mayo-Clinic-Study-Calls-For-Screening-Of-Family-Members-Of-Celiac-Disease-Patients.aspx

Wow unbelievable. 

Cycling lady have excellent info. I just wanted to stop in thread and say welcome Debra. I wish your grand daughter well.