Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Oral And Rectal Challenge Testing Of The Mucosa


ravenwoodglass

Recommended Posts

ravenwoodglass Mentor

There has been some recent debate on whether gluten is absorbed into the system through any mucosa other than the intestines. In the US mucosal testing is unheard of they would rather make us sick for weeks or months to do an expensive and inherently risky endo and biopsy. Other countrys have found that that torture may not be needed and that by using a gluten laden patch or infusion or suppository that the histological changes can be detected in the mucous membranes within a relatively short time. There are many more articles out there a search of rectal or mucosal challenge and celiac will bring them up.

Here is one study on the use of detecting celiac through rectal mucosa challenge off of Pub Med

Open Original Shared Link

And another

Open Original Shared Link

And one last one on nasal mucosa testing

Open Original Shared Link


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Nancym Enthusiast

None of those links worked for me!

psawyer Proficient

Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

ravenwoodglass Mentor
Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

They were pasted and I did not realize they would not open after pasting. I'll see if I can correct that. Thanks for posting the link to the other post.

One real good reason for us to get this info out is it would be nice if US doctors knew about some of the less invasive forms of testing and hopefully if people ask their GI doctors about it and show them some of the studies on the validity of mucosal testing we can get it used in the US and more people will be able to be diagnosed without having to be made ill to do so.

Edit I think I was able to fix the problem. Thanks guys seems the world forces me to be more computer literate every day, whether I want to or not.

  • 4 years later...
domesticactivist Collaborator

I just had someone tell me about Cyrex labs cross-reactivity tests and when I went to their site saw that they offer Mucosal Gluten Reactivity Screen that I'd seen mentioned here on this site a couple times. I'm very interested to learn more about this.

Open Original Shared Link

Does anyone have neutral information on the validity of the Cyrex labs tests?

Skylark Collaborator

Does anyone have neutral information on the validity of the Cyrex labs tests?

That's just salivary IgA. It's no better validated than fecal.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      128,595
    • Most Online (within 30 mins)
      7,748

    Donnadabb
    Newest Member
    Donnadabb
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.1k
    • Total Posts
      71.1k

  • Celiac.com Sponsor (A22):




  • Who's Online (See full list)

    • There are no registered users currently online

  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • CelluloseSick
      Thanks Scott. its been a tough journey. i haven’t been able to take any painkillers for pain, because they all contain some form of cellulose. I’m finally working with a compounding pharmacist to get compounded Ibuprofen w/o cellulose filler … I’ll let you know how that works out. when I tell doctors about my problems with cellulose and medications, sadly they really don’t understand the magnitude of the problem. My reason for responding to the original post was to let others know they’re not crazy - and there’s such a thing as cellulose intolerance. Thank you so much for your response.
    • Scott Adams
      Hello @CelluloseSick, it sounds like you’ve been through a really challenging journey trying to pinpoint and avoid cellulose fillers in medications. Severe migraines and liquid diarrhea, especially with Ulcerative Colitis, must make this an incredibly difficult issue to manage. It’s frustrating how hidden these ingredients can be, and it definitely takes a lot of detective work to connect the dots. While true cellulose allergies or intolerances don’t seem to be well-documented, some people do report digestive issues, headaches, or other symptoms when exposed to cellulose-based fillers. Unfortunately, there isn’t a clear statistic on what percentage of the population suffers from this, but anecdotal evidence suggests that you are not alone. Have you found any specific resources or medical professionals who acknowledge this issue? It’s great that you’ve been able to find compounded medications with sucrose fillers—hopefully, that continues to work for you!
    • CelluloseSick
      Btw, I recently switched from Compounded T3/T4 ( which had cellulose in it, unbeknown to me) and was making me sick to a brand called NP Thyroid. No cellulose filler
    • CelluloseSick
      So happy to have found this Post. ive been struggling with cellulose fillers in meds for years. When I found out, I looked for meds that do not contain cellulose filler or have had to get compounded meds made with sucrose filler. My reactions are:  severe migraines and liquid diarrhea ( not fun when you suffer from Ulcerative Colitis). not sure what percentage of the population suffer from such allergy. you'd have to be a pretty good sleuth to find this and make the connections. Bravo for you!   anyone know what percentage of population suffers from cellulose intolerance? thanks?    
    • Scott Adams
      If you replace the gluten products you normally ate with gluten-free versions, and I mean the breads, be careful, as many gluten-free products can be high in calories and low in nutrients (high carb).
×
×
  • Create New...