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Dgp/iga Results Positive

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Hi all, I just recvd panel back. All neg except the new GDP IGA came back 38. GDP IGG was neg. Doc wants me to see GI. With only one positive test but supposedly quite accurate can I assume celiac disease? I have bloating, gas, nausea and sometimes just don't feel well.

Mainly need to know if worth getting scoped on only one positive test. Help!!

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Hi all, I just recvd panel back. All neg except the new GDP IGA came back 38. GDP IGG was neg. Doc wants me to see GI. With only one positive test but supposedly quite accurate can I assume celiac disease? I have bloating, gas, nausea and sometimes just don't feel well.

Mainly need to know if worth getting scoped on only one positive test. Help!!

I just came across your post and realize it's been awhile so I'm not sure if you'll get this. I just had a positive only GDP biopsy and was wondering what your biopsy came back. Thanks!

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gfcolorado, are you saying that only your deamidated gliadin was positive and your biopsy was positive, too?

I ask because my only antibody that came back positive was the deamidated gliadin at a 31. I did not get the scope because I had one done about 10 years ago looking for the same thing. I never did get the results, though, just told it was ok. I'm actually going to go pick them up this week to see for myself what they say.

Just curious! Thanks!

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I just got my results back I had deamidated gliadin antibodies at 36, along with a DQ8 gene (I got the genetic test at the same time). Other tests were negative. I have major celiac symptoms. I'm having the scope done next week. My GI Dr, who was recommended to me by a local celiac support group, said this test was a very strong indication that I do have celiac. From what I've read this test is very specific to celiac, and a valuable new test in detecting celiac in patients, like me, who have tested negative with the other tests.

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Wow. It sounds like a lot more people with only the positive DGP. I guess that I need to go retest and find a GI. I would be very grateful if you update after your scope!

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DGP is considerably more sensitive than the other tests in the celiac panel.

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My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

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My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

Don't be bummed get on the diet. If your DGP was positive you do need to avoid all gluten. False negative biopsies are very common. Get on the diet strictly and you should be feeling better soon.

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My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

You do have hope to feel better. My mom came back negative on antibodies and biopsy. She feels a heck of a lot better off gluten. With the DGP there is certainly something going on and you might be pleasantly surprised.

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My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

My biopsy was normal, too. My GI doc dismissed me without any follow up to discuss my obvious Celiac symptoms. According to him (and a lot of docs), if the biopsy was negative, I don't have a problem. What an idiot. :angry:

When my rheumatologist took one look at my DGP levels, he said it was most certainly Celiac and to avoid gluten like the plague. :o DGP is very specific for Celiac, so in his opinion, it trumps the biopsy because of the false negative probability if the damage is patchy in the intestines.

I am now one month gluten free, and my stomach issues are 80% better than before! I think you will be pleasanly suprised by how good you will feel off of gluten! B)

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gfcolorado, are you saying that only your deamidated gliadin was positive and your biopsy was positive, too?

I ask because my only antibody that came back positive was the deamidated gliadin at a 31. I did not get the scope because I had one done about 10 years ago looking for the same thing. I never did get the results, though, just told it was ok. I'm actually going to go pick them up this week to see for myself what they say.

Just curious! Thanks!

When I was originally tested 3 years ago, all my tests (TTG, EMA, DGP) were positive and so was my biopsy. This time, only my DGP was positive. My TTG and EMA were negative. I think I'm going to get another endoscopy just to see what's going on. If I do, I'll let you know.

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My biopsy was normal, too. My GI doc dismissed me without any follow up to discuss my obvious Celiac symptoms. According to him (and a lot of docs), if the biopsy was negative, I don't have a problem. What an idiot. :angry:

When my rheumatologist took one look at my DGP levels, he said it was most certainly Celiac and to avoid gluten like the plague. :o DGP is very specific for Celiac, so in his opinion, it trumps the biopsy because of the false negative probability if the damage is patchy in the intestines.

I am now one month gluten free, and my stomach issues are 80% better than before! I think you will be pleasanly suprised by how good you will feel off of gluten! B)

I think there is so much they still don't know about Celiac and Gluten Sensitivity and the DGP test. When I went to a Celiac conference about 3 years ago, they hardly talked about Gluten sensitivity. When I went last year, the top Celiac researchers all talked about it. Most doctors say that you don't have Celiac until your biopsy is positive and no one really knows at what point you become positive. I had really bad stomach aches my whole life but wasn't diagnosed with Celiac until I was 43. My biopsy was positive and my stomach aches are gone but would I have tested positive when I was a kid or 10 years prior? I don't know but going off of gluten would have made my stomach aches go away and might have prevented villous atrophy and other auto immune diseases.

Thanks everyone for sharing your info!

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Yall were right! After about 11 days gluten free my energy levels picked up and I have felt incredible...more energy, anxiety is gone, more focus...I have not felt this good in years. Now I'm going to patiently wait for my physical problems to improve! It's almost miraculous. To think had I not figured this out on my own, I would've lived out the rest of my life completely miserable. Doctors are grossly mis/uneducated about this!! All the time n money spent on Dr visits and tests, when the whole time it was food. :/ I consider myself lucky. So many suffer so much longer and never know how poisonous gluten can be. It should come with a warning label!

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That's wonderful news! I'm so glad to hear you're feeling better. Thanks a lot for coming back to update us and share your good news!

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