Jump to content

  • You are not alone. Join Celiac.com for trusted gluten-free answers and forum support.



  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

Celiac cure

yashkanthale
 Share

Recommended Posts

yashkanthale Newbie
yashkanthale
Posted

Hello, This is Yash Kanthale, From India, Maharashtra. (Celiac Patient)

I herd that there is some research going on treatment of celiac decease and also the clinical trials is at phase 2 level and they have found the treatment which can reverse the celiac decease. The research is in the link below:

https://www.sciencedaily.com/releases/2019/10/191022080723.htm

And also Research on CNP-101 And TAK-101 Medicine and let me know.

I want to ask that is it true that when final phase is done we can treat celiac decease and can actually reverse the celiac decease, please let me know after your research on this article. Thank you!!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


trents Grand Master
trents
Posted
(edited)

"After treatment with the technology, the patients were able to eat gluten with a substantial reduction in inflammation . . . Celiac patients treated with the COUR nanoparticle, CNP-101, showed 90% less immune inflammation response than untreated patients. By stopping the inflammatory response, CNP-101 showed the capacity to protect the intestines from gluten related injury."

Let's be clear. The researchers connected with this project are not saying it eliminates the need to eat gluten-free. But this has great promise for protecting against damage from cross-contamination/incidental types of gluten exposures where the amount of gluten consumed is minor. And most of us would be very happy with that if it turns out to hold true after all the testing is done. How many phases are there to these kind of trials anyway?

Of course, the worry I have here is that many Celiacs would let their guard down and cheat too often in their gluten-free living.

Edited by trents
Posterboy Mentor
Posterboy
Posted

Yash,

Being from India your over reliance on Rice might be causing you to have low Thiamine levels where Beri Beri is still common.

I like your research but it doesn't answer the question of persistent inflammation outside the GI track and through the whole body.

See this research that shows how taking Baking Soda might help with that....it explains well how our body goes into inflammation mode when we get low in Acetylcholine...

https://www.medicalnewstoday.com/articles/321624

And someone who has developed Beri Beri would be low in Acetylcholine....

Here is a nice article about how Acteylcholine is used by the body to regulate it's functions through out the body...

https://www.peirsoncenter.com/articles/acetylcholine-how-and-why-to-optimize-the-synthesis-of-this-vital-neurotransmitter

And being low in Thiamine can lead to thin Villi in mammals.  Try taking some Benfotiamine to see if it helps you fell better......It should help most of your fatigue issues.....if you are having any yet?

Also see this posterboy blog post that discusses how Thiamine supplementation can be used by Celiac's.

I hope this is helpful but it is not medical advise.

Posterboy,

trents Grand Master
trents
Posted

I realize we are straying a bit off topic but rice can also be high in arsenic. Where arsenic is present in the soil, rice is naturally good at taking it up.

knitty kitty Grand Master
knitty kitty
Posted

Thiamine is a known chelator of arsenic and other heavy metals like lead.  Thiamine in the form of TTFD is used...

https://europepmc.org/article/med/12195231

https://www.hormonesmatter.com/chelation-therapy-medicine/

 

DJFL77I Experienced
DJFL77I
Posted

but how far away is it from actually being fda approved?  50 years?

DJFL77I Experienced
DJFL77I
Posted

https://wbbm780.radio.com/articles/nu-finds-new-treatment-may-reverse-celiac-disease

In an industrial collaboration project, TU Wien has developed a medication that can alleviate or even completely eliminate the symptoms of celiac disease. It should be available as early as 2021. Celiac disease is a fairly common disease, affecting one to two percent of the European population.

https://medicalxpress.com/news/2018-09-remedy-celiac-disease.html

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


DJFL77I Experienced
DJFL77I
Posted

https://ueg.eu/week/register?gclid=CjwKCAjw19z6BRAYEiwAmo64Lbs34JpzWB8bJALq5RIyFxB30cp-TbZuk9XHMAdz2oNonZEJZ2WKmxoCshAQAvD_BwE

yashkanthale Newbie
yashkanthale
Posted
  • Author
1 hour ago, DJFL77I said:

but how far away is it from actually being fda approved?  50 years?

I don't know but soon.. 

yashkanthale Newbie
yashkanthale
Posted
  • Author

 

I don't know but soon.. 

yashkanthale Newbie
yashkanthale
Posted
  • Author
1 hour ago, DJFL77I said:

https://wbbm780.radio.com/articles/nu-finds-new-treatment-may-reverse-celiac-disease

In an industrial collaboration project, TU Wien has developed a medication that can alleviate or even completely eliminate the symptoms of celiac disease. It should be available as early as 2021. Celiac disease is a fairly common disease, affecting one to two percent of the European population.

https://medicalxpress.com/news/2018-09-remedy-celiac-disease.html

I hope and excited to hear that and also iam waiting for that thanks for sharing!!!!

DJFL77I Experienced
DJFL77I
Posted

https://www.beyondceliac.org/research-news/drug-to-treat-celiac-disease-gets-to-furthest-ever-stage-of-study/

Innovate Biopharmaceuticals today announced that is has given the first dose of larazotide acetate to a study participant. Larazotide acetate is the first celiac disease drug to get to a critical, large-scale Phase 3 clinical trial.

Phase 3:  The stage of clinical trial in which researchers demonstrate whether a drug offers a treatment benefit to a specific population. This phase involves 300 to 3,000 volunteers who have the disease or condition and typically lasts one to four years. It is part of the Food and Drug Administration approval process.

trents Grand Master
trents
Posted
(edited)

It should be cautioned that neither of these two articles claim to completely eliminate the need to eat gluten free. Both seem to target incidental gluten exposure such as we get from cross contamination. Here's a quote from the first article:

"Northwestern claims after celiac patients were treated with the technology, they were able to eat gluten and experience far less inflammation. The results also show a trend toward protecting patients’ small intestine from gluten exposure."

Notice it says, "far less inflamation". 

And from the second linked article: ""It remains to be seen whether the symptoms will disappear completely or will only be alleviated. The precise effects will probably vary from person to person."

Edited by trents

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Scott Adams
      0

      Gluten-Free Bulgogi Beef: A Sweet and Savory Korean Barbecue Favorite

    2. xxnonamexx
      - xxnonamexx posted a topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      0

      Breakfast ideas besides oatmeal as Avenin can be gluten?

      I read gluten-free oatmeal Avenin can cause gluten like symptoms. I read Bobs Redmill gluten-free creamy buckwheat cereal and Millet are good alternatives with ultra low heavy metals, mold but it seems it takes longer to prepare the minute oats. What have you changed your breakfast to.
    3. RMJ
      - RMJ replied to Ginger38's topic in Coping with Celiac Disease
      5

      The Struggle Has Overtaken Me

      Ginger38, that sounds very difficult. Each dietary restriction makes it harder to figure out what to eat. Before my celiac diagnosis I already watched out for my cholesterol level and migraine triggers, but those are much easier than diabetes restrictions. One “bad” meal isn’t that much of a problem for cholesterol levels, and my migraines only happened if I ...
    4. Aretaeus Cappadocia
      - Aretaeus Cappadocia replied to Ginger38's topic in Coping with Celiac Disease
      5

      The Struggle Has Overtaken Me

      Reading the original post on this thread made me think of "How To Eat An Elephant". The key point is that a whole, big problem can seem insurmountable but if you break it into bite-sized pieces it is much easier to accomplish. Here is the google description. It's not bad: If you're facing a daunting goal, you can use these steps to "eat your elephant...
    5. Aretaeus Cappadocia
      - Aretaeus Cappadocia replied to Xravith's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      Gluten challenge - Need some guidance

      I don't know the answer to your question any better than a google search, but I am sure someone else will step up and answer. I am popping up to recommend that you keep a careful diary (in case you weren't already). Try to catalog what you are eating and experiencing. Bring a copy to your next visit (and if you have access to the Dr, also send a copy...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      134,180
    • Most Online (within 30 mins)
      10,442
    Nancy sirois
    Newest Member
    Nancy sirois
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Who's Online (See full list)

  • Upcoming Events

  • Posts

    • xxnonamexx
      Breakfast ideas besides oatmeal as Avenin can be gluten?

      By xxnonamexx · Posted

      I read gluten-free oatmeal Avenin can cause gluten like symptoms. I read Bobs Redmill gluten-free creamy buckwheat cereal and Millet are good alternatives with ultra low heavy metals, mold but it seems it takes longer to prepare the minute oats. What have you changed your breakfast to.
    • RMJ
      The Struggle Has Overtaken Me

      By RMJ · Posted

      Ginger38, that sounds very difficult.  Each dietary restriction makes it harder to figure out what to eat. Before my celiac diagnosis I already watched out for my cholesterol level and migraine triggers, but those are much easier than diabetes restrictions. One “bad” meal isn’t that much of a problem for cholesterol levels, and my migraines only happened if I consistently ate the triggers. After many years I’ve figured out how to bake gluten free but I think many recipes have more starch which wouldn’t work for diabetes. If you go with the elephant eating analogy, I think the first portion to work on would be the diabetes, since the immediate consequences of not being careful (passing out from low blood sugar, or diabetic coma from high blood sugar) are so severe. The next portion would be celiac. The serious consequences aren’t as immediate, but if you have celiac disease, I think of eating gluten like a booster shot - revving up the immune system, but to attack yourself leading to long term damage. It sounds like you are experiencing this damage now. I did a google search on “gluten free food for diabetics” and a number of sites with advice came up.  If your insurance will cover it and you can find one, a registered dietician who knows about both diabetes and celiac disease might help you figure out what to eat safely. Hopefully my post will both scare and encourage you, as requested, with a big dose of compassion because this sounds very difficult and you are clearly suffering.
    • Aretaeus Cappadocia
      The Struggle Has Overtaken Me

      By Aretaeus Cappadocia · Posted

      Reading the original post on this thread made me think of "How To Eat An Elephant". The key point is that a whole, big problem can seem insurmountable but if you break it into bite-sized pieces it is much easier to accomplish. Here is the google description. It's not bad: If you're facing a daunting goal, you can use these steps to "eat your elephant": Identify the Elephant: Clearly define the large project or goal that feels overwhelming. Break it Down: Divide the major task into smaller "bite-sized" pieces. If a piece still feels too big, break it down further. Prioritize: Decide which "bite" to take first based on necessity or impact. Focus on the Now: Instead of worrying about the whole animal, focus only on the single step you are taking right now. Maintain Consistency: Progress comes from taking the "next right step" every day until the task is complete. Celebrate Small Wins If I understood Ginger38's post correctly, you are facing the prospect of a gluten challenge, but you are already eating gluten on an intermittent basis. It also sounds like many of the symptoms you attribute to gluten consumption are in full expression. Step back and take a deep breath. Get a notebook and start a gluten-related diary. Don't try to make it perfect; just record what you can about food intake and what you experience as you go along. Talk to your Dr's office (nurse, Dr, whomever) about the challenge. The most rigorous challenge is for someone who has already gone truly gluten free but now needs a clear diagnosis. Someone who is already eating gluten should not need as much "challenge". Even at that, google describes an example challenge as 1-2 slice of bread or 1/2 cup of pasta a day. If that describes your existing diet you are already there. For the moment, try to focus on getting past the challenge and test. Once you have the results, start planning accordingly.
    • Aretaeus Cappadocia
      Gluten challenge - Need some guidance

      By Aretaeus Cappadocia · Posted

      I don't know the answer to your question any better than a google search, but I am sure someone else will step up and answer. I am popping up to recommend that you keep a careful diary (in case you weren't already). Try to catalog what you are eating and experiencing. Bring a copy to your next visit (and if you have access to the Dr, also send a copy a couple days in advance). Don't assume that they will read it. They might, but they also might be under tremendous time pressure and not get to it. Two other suggestions: if your healthcare provider has a web portal, sign on and search for "gluten challenge". They may have a standard page and Dr assumed you would find it on your own. If that doesn't work, call the Dr's office and ask the office for their official advice. You probably wouldn't need to speak to the Dr directly. There should be some nurse or staff member who could answer that
    • Xravith
      Gluten challenge - Need some guidance

      By Xravith · Posted

      After few months going gluten free, I decided to reintroduce gluten in my diet so I can do a proper diagnosis for Celiac disease. During the gluten free period I felt incredibly good. I stopped having hypoglycemia symptoms, I gained some muscle (Still, I am considerably underweight) and my anxiety totally disappeared. I felt totally like a new person. Now, I almost reached the second week of gluten challenge and all my symptoms are progressively coming back. The first days I was ok, just a bit of acid reflux I could control with medicines. However, after the first week I started to feel real stomach pain and tiredness, my face is growing acne and sometimes (specially when I walk) i feel painful migraines.  I am afraid If I am eating too much gluten or not enough, the "4 slices of bread" indication confuses me. I am actually eating 20 g of bread, 3 biscuits and 40 g of croissant each day. My doctor was not very specific when he gave me the medical order for the gluten challenge, so I invented my own daily gluten menu. Do you have any suggestions? 4 weeks will be enough to do the blood test with my current gluten intake?  Thank you
×
×
  • Create New...