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Half full

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Everything posted by Half full

  1. Half full
    I had the capsule endoscopy done, because I had a mild anemia as well. I do have some positive celiac antibodies as well (TTGA about 30 and Gliadin Igg about 40-45), but two endoscopies had negative biopsies. The capsule endoscopy was to look for ulcers or Chrohn's, but my GI doctor said sometimes they can see celiac as well. My capsule endoscopy showed...
  2. Half full
    I must be DQ7.5, since Prometheus reported I have DQA1 05, half the heterodimer (and DQ2 and DQ8 negative). From what I can tell the only possibility would be DQA1 05 - DQB1 03, which is DQ7.5.
  3. Half full
    The 4 celiacs with no part of dq2 heterodimer break down as follows: DQ5/DQ5 DQ4.4/DQ5.1 DQ4.4/DQ5.1 DQ7.3/DQ9.2 Sorry, no DQ6. But with only 4 samples, I don't know if you can draw any conclusions. With DQ2.2, it depends what is paired with. DQ2.2/DQ2.5 can produce the DQ2.5 heterodimer and 50% of the produced isoforms are dq2.5. ...
  4. Half full
    Thank you for the great article on haplotypes of celiacs. Here are some statistics from the 1008 celiacs from Europe. DQ2 positive 88% DQ8 only 6% DQ2 and DQ8 negative 6% (1/2 DQ2 heterodimer) no part of DQ2 heterodimer 0.4% (4 out of 1008 celiacs). Of the 1/2 DQ2 heterodimer celiacs: ...
  5. Half full
    Thank you for the link about DQ7.5. I have a science background, and it's fascinating for me to read about these genes and their proteins, even though some of the details are hard to grasp. I'm going to research DQ7.5 celiac to see if there are any particular presentations associated with it. If anyone has any special knowledge, please chime in. Thanks...
  6. Half full
    Thank you for your reply. I do not have a specific haplotype (?) result. All I have from Prometheus is that HLA DQA1 05 was detected, and that I am DQ2 and DQ8 negative. They state that some celiacs do have half the DQ2 heterodimer. Your reply confirms my reading in that most half DQ2 celiacs have the beta subunit and that celiacs with the alpha unit...
  7. Half full
    Hi all, I'm a newbie to the forum, thank you already for the valuable information I've read from this web site. I'm currently in the middle of a nine month gluten free diet, and drawing blood every few months for the antibodies. My question is about the genetic profiles. I am HLA-DQ2 and HLA-DQ8 negative, but positive for the HLA DQA1 05 allele...
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