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Can Everyone Post Their Genes

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Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula


gluten, casein and soy free

on low carb/low sugar diet

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Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8):


Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)


gluten, casein and soy free

on low carb/low sugar diet

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my step-sons are

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 2,1 (Subtype 2,6)


gluten, casein and soy free

on low carb/low sugar diet

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I like Gloria Vanderbilt...oh genes. Don't know mine, a biopsy sealed it for me. ;)


Lisa

Gluten Free - August 15, 2004

"Not all who wander are lost" - JRR Tolkien

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Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula

Oh my gosh! Do you guys actually know what all that means? If I have this test done eventually, will someone interpret it for me? Yikes!

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Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)


4/2007 Positive IGA, TTG Enterolab results, with severe malabsorption: Two DQ2 celiac genes--highest possible risk.

gluten-free since 4/22/07; SF since 7/07; 3/08 & 7/08 high sugar levels in stool (i.e. cannot break down carbs) digestive enzymes for carbs didn't help; 7/18/08 started SCD as prescribed by my physician (MD).

10/2000 dx LYME disease; 2008 clinical dx CELIAC; Other: hypothyroid, allergies, dupuytrens, high mercury levels

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Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine


Nadine

mom of 4 great kids - 2 diagnosed with autism and 2 typical kids (thank goodness)

all this started after my hysterectomy in March of 2006

G.F. since Feb 2007

Soy free since April 2007

Blood work was negatvie (after 2 weeks of being on the gluten-free diet)

entrolab results:

Antigliadin 9 (normal <10)

HLA-DQB1 Allele 1 - 0302

HLA-DQB2 Allele 2 - 0502

HLA-DQ 3,1 (subtype 8,5)

carrying one celiac gene and one gluten intolerant gene

nurse at entrolab figures i caught this early and dont eat gluten anymore

life is like a box of chocolates;sometimes you get stuck with the yukky coconut fillet one

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Today - Old Navy.

Normally - Levis

But I'm working on switching the wardrobe to organic cotton.

I don't know my Gene's despite paying for the test from Enterolab. I'd have to look. I was diagnosed both by biopsy, diet, and Enterolab. Having had so many wrong diagnosis-es over the years, there was really no way I was going to let any one test change my life. All three pretty much confirmed each other, and that sealed the deal.

Geoff


Celiac - Gluten Free since Late December 2006

Positive Dietary response, biopsy, Enterolab

Lactose intolerant - dietary response test only

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Mine are in my signature because I can never remember what they are.

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I never had the gene test done so I only know from deduction what mine are since my parents had theirs done. My mother's was:

HLA-DQB1 Molecular analysis, Allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0501

Serologic equivalent: HLA-DQ 3,1 (Subtype 8,5)

and my dad's was:

Serologic equivalent: HLA-DQ 3,3 (Subtype 7,7)

Since my dad has a double gene I know I have the 7 and then either an 8 or 5 from my mother. Interestingly enough even though it's my mother that has the celiac gene it was my dad that tested positive for gluten intolerance. My brother is postive as well and he has the 7 and 8 genes.

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Here's my Enterolab gene test results. Everyone who tests with Elab will get an explanation of their genetic (and other test) results. I also posted the interpretation included in my Elab gene test results:

Gene Test for Gluten Sensitivity

Molecular Analysis: HLA-DQB1*0602, 0302

Serologic equivalent: HLA-DQ 1,3 (subtype 6,8)

HLA gene analysis reveals that you have a copy of one of the main genes that predisposes to gluten sensitivity and celiac sprue, HLA-DQ3, subtype 8 (HLA-DQ8). This genotype also can predispose to microscopic colitis and other autoimmune syndromes.

BURDEE


Gluten, dairy, soy, egg, cane sugar, vanilla and nutmeg free. Enterolab diagnosed gluten/casein intolerant 7/04; soy intolerant 8/07. ELISA test diagnosed egg/cane sugar IgG allergies 8/06; vanilla/nutmeg 8/06. 2006-10 diagnosed by DNA Microbial stool tests and successfully treated: Klebsiella, Enterobacter Cloaecae, Cryptosporidia, Candida, C-diff, Achromobacter, H. Pylori and Dientamoeba Fragilis. 6/10 Heidelberg capsule test diagnosed hypochloridia. Vitamin D deficiency, hypothyroiditis, hypochloridia and low white blood cells caused vulnerability to infections. I now take Betaine HCl, probiotics, Vitamin D and T3 thyroid supplement to maintain immunity.

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Mine:

HLA-DQB1*0602, 0609

Daughter's:

HLA-DQB1*0609, 0301

Son's:

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

..........................

Husband hasn't had his done, but he obviously has at least one copy of HLA-DQB1 Molecular analysis, Allele 1 0301 .

Nancy


The person who says it cannot be done should not interrupt the person who is doing it.

~Chinese Proverb

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Thanks everyone that posted. I had some thoughts going threw my head yesterday and wanted to compare gene types, and see who had genes like mine. Plus i want to do some research on gene types sometime in the near future. I have to much going on right now to think straight, but it is on my 2 to list lol

paula


gluten, casein and soy free

on low carb/low sugar diet

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Mine are in my signature because I can never remember what they are.

:D Mine, too!


Patti

"Life is what happens while you're busy making other plans"

"When people show you who they are, believe them"--Maya Angelou

"Bloom where you are planted"--Bev

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heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine

Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

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Hi

Please below my name. You will find them.


Have not I commanded you? Be strong and of a good courage; be not afraid, neither be thou dismayed: for the LORD thy God is with you every where you go.

Jos 1:9

I can do all things thru Christ which strengtheneth me.

Phi 4:13

Blood Test: Negative 03/2006

Biopsy Negative 04/2006

Stopped gluten-free diet 04/2006

EnteroLabs: Positive 04/2007

Fecal Antigliadin IgA "Positive"

Fecal Antitissue Transglutaminase IgA "Positive"

Quantitative Microscopic Fecal Fat Score "Positive"

Fecal anti-casein (cow

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Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

See this is one of the things that i am really interested in. I am dqb1 0301, which i think is very close to dqb1 0302. I am not sure how close they are but would really like to find out.

paula


gluten, casein and soy free

on low carb/low sugar diet

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Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

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DQ 3 (7)

DQ 3 (8)


Suzanne

2/07

EnteroLab

Antigliadin IgA [pos.]

Antitissue Transglutaminase IgA [pos.]

Anti-Casein IgA antibody [pos.] {how very sad}

HLA-DQ3 (subtype 8)

HLA-DQ3 (subtype 7)

Gluten free 3/18/07

Casein (very light) 3/18/07

constipation/dysmotility since birth

severe headaches 11/83

hypothyroidism 4/00

B-12 defficiency 10/04

"GERD" 1/06 "Gastritis" 3/06

"IBS" (forever) 3/06

depression w/ pain 4/06

iron defficiency anemia (off and on forever) 12/06

celiac disease 3/07

plus.....

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close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula


gluten, casein and soy free

on low carb/low sugar diet

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Mine: HLA-DQ 2,3 (subtype 2,7) or DQ2 and DQ7

Husband: HLA-DQ 2,3 (subtype 2,8) or DQ2 and DQ8

Daughter:HLA-DQ 3,3 (subtype 8,7) or DQ8 and DQ7

Son: HLA-DQ 2,2 (subtype 2,2) or Double DQ2

Son: Haven't gene tested yet but DQ2, 7 or 8 are the only possibilities.


Andrea

Enterolab positive results only June 06:
Me HLA-DQB1 Molecular analysis, Allele 1 0201; HLA-DQB1 Molecular analysis, Allele 2 0301; Serologic equivalent: HLA-DQ 2,3 (subtype 2, 7)
Husband HLA-DQB1 Molecular analysis, Allele 1 0201; HLA-DQB1 Molecular analysis, Allele 2 0302; Serologic equivalent: HLA-DQ 2,3 (subtype 2,8)



The whole family has been soy free since February, gluten free since June 2006.

The whole family went back to a gluten diet October 2011.  We never had official testing done and I decided to give gluten a go again.  At this point I've decided to work on making some gluten free things again, though healthwise everyone seems to be fine.  The decision to add gluten back in was also made based on other things I'd read about the 2nd sequence of genes.  It is my belief that we had a gluten intolerance, but thanks to things I've learned here, I know more what to keep an eye on.  If you have a confirmed case of celiac, please don't go back to gluten, it's a lifelong lifestyle change.

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thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Paula,

You are welcome :).

I've found the best info online. go to wikipedia, and search for hla dq2, and click on the first link...I think its a great comprehensive overview of the hla dq genes of interest to us.

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Thanks for that info. Yesterday i just kept typing in the difference between 7 and 8, i didnt hink to type just in 7 lol. I am going to try and do some more research today. I even emailed enterolab to see what they will tell me, I am sure i wont hear from them til next week tho.

paula


gluten, casein and soy free

on low carb/low sugar diet

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