- Celiac Disease Research: Associated Diseases and Disorders
- Casein / Cows Milk Intolerance and Celiac Disease
- Disaccharidase Activity as a Diagnostic Criterion for the Mucosa of the Small Intestine
Disaccharidase Activity as a Diagnostic Criterion for the Mucosa of the Small Intestine
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TI- Disaccharidasen-Aktivitaten als Beurteilungskriterium
AU- Stern M; Plettner C
JN- Monatsschr Kinderheilkd; 131 (5) p264-8
PY- May 1983
of lactase, sucrase, and maltase were determined in small intestinal
biopsies of 125 children with Coeliac disease, cows milk protein
intolerance, transient gluten intolerance, nonspecific enteropathies,
and controls. Four cases of primary disaccharidase deficiencies could
be identified. In the enteropathies, morphometric data were more closely
correlated to the degree of the mucosal lesion (r = -0.92 for crypt
depth) than were disaccharidase activities (r = 0.61 for lactase).
In a stepwise discriminate analysis of the patient groups, based upon
immunological, morphometric, and biochemical variables, lactase activity
was a valuable secondary criterion, ranking third among the variables
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