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Thiamine and IgA production

Antibody production and Thiamine

I found these neat articles. B cells defined by immunoglobulin isotypes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985177/ And... Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B1 https://pubmed.ncbi.nlm.nih.gov/26411688/ And... Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478888/ A
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Thiamine and IgA production

Thiamine and Decreased IgA production

https://www.frontiersin.org/articles/10.3389/fnut.2019.00048/full Previously, we examined B cell immunometabolism in the intestine. In the intestine, naïve immunoglobulin (Ig) M+ B cells differentiate into IgA+ B cells in Peyer's patches (PPs) by class switching, and then IgA+ B cells differentiate into IgA-producing plasma cells in the intestinal lamina propria (20). Naïve B cells in PPs preferentially use a vitamin B1-dependent TCA cycle for the generation of ATP. However, once the B cell
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