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Gluten Opioids


Joyous

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Joyous Enthusiast

Where can I find some good information about gluten opioids?


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cruelshoes Enthusiast

Her are some to get you started.

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Gluten intolerance, in Autism, is thought to be related to the incomplete digestion and breakdown of proteins. Normally, proteins are digested by enzymes in the intestines and are broken down into long chain amino acids. With maldigestion, short chains of these amino acids, known as peptides, will develop in excess amounts and enter the bloodstream. Peptides from proteins such as gluten and casein, called "exorphins," are biologically active. They interact with opiate receptors in the brain and have the same effects as opiate drugs like heroin and morphine and are also addictive. There are 15 opioid sequences in one molecule of gluten. (13) In fact, the peptides can be up to 30 times more potent than morphine.

The effects of opioids on the body are numerous. (14) "Opioid peptides are key signaling molecules between the endocrine, immune, brain nerve tissues, and the pineal complex, the latter is particularly associated with circadian rhythms." (15) Any abnormal alteration in the quantity of these peptides will have a detrimental effect on all of these systems. Some of the other effects on the body are decreased gastric acid secretion, reduced glutathione levels, immune system depression and modulation of cholecystokinin levels. All of these effects contribute to the inhibition of normal brain, bodily function and growth.

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People with celiac disease have a hereditary, genetic predisposition to allergic reaction to gluten in their digestive system and must avoid it entirely. People with autism and autistic spectrum disorders, like Asperger's syndrome, may be sensitive to gluten and casein (a protein in milk); both seem to have an opiate-like effect on these people. The opioid effect of gluten is caused by gluten exorphines and gliadorphin. These are peptides formed in the digestion of gluten. See more at gluten-free, casein-free diet. Another condition which may cause one to follow a gluten-free diet is dermatitis herpetiformis.

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    • DebD5
      Thank you so very much. 
    • Scott Adams
    • DebD5
      What artice?
    • Scott Adams
      Good point, as thyroid conditions are more common in those with celiac disease: https://www.celiac.com/celiac-disease/celiac-disease-amp-related-diseases-and-disorders/thyroid-pancreatic-disorders-and-celiac-disease/
    • Scott Adams
      @DebD5 it sounds like you are in the super sensitive celiac disease zone--and if so your reactions are real, and not psychological, as your doctor implied.  It's also possible you have other dietary triggers so be sure to look at that article in my last post in this thread.
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