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Getting Blood Work Done/symptoms


redheadsmom

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redheadsmom Rookie

I'm new here and so glad I found this forum! I have been suffering from all sorts of things since I was about 15 years old, I'm 31 now. I'm going in this afternoon for blood work to test for Celiac. I have been tested before and the results were negative but from what I have been reading that's not uncommon. I was diagnosed with psorasis when I was 15, began having bowel problems after my son was born when I was 18 and around age 25 severe heartburn. I have had a colonoscopy, and endoscopy and everything turns out fine. Lately my symptoms have increased and I have been having lots of bloating, cramping, and major gas pains. Does this sounds like typical symptoms for Celiac? Is is possible to test positive a few years after testing negative? If my test is negative again should I push for another endoscopy which showed nothing about 5 years ago? Thanks for any help!

Jessica


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    • trents
      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      This article, and the comments below it, may be helpful:    
    • Scott Adams
      That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people with celiac or DH don’t react every time they’re exposed, so lack of symptoms doesn’t rule it out. Given your history and family cancer risk, this is something I’d strongly discuss with a celiac-experienced gastroenterologist or dermatologist before attempting a challenge on your own, so risks and benefits are clearly weighed.
    • Greymo
      https://celiac.org/glutenexposuremarkers/    yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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